Publications by authors named "Haiyun Jiang"

This study explored the comorbid mechanisms between Crohn's disease (CD) and chronic obstructive pulmonary disease (COPD) using bioinformatics analysis. From the Gene Expression Omnibus (GEO) microarray dataset, 349 common differentially expressed genes (coDEGs) were identified, and 8 shared hub genes were found: CCL2, CXCL1, TLR2, ICAM1, PTPRC, ITGAX, PTGS2, and MMP9, which were vital for immune function and regulation of inflammatory responses. In addition, the study also analyzed the association between coDEGs and immune cell infiltration using the single-sample gene set enrichment algorithm (ssGSEA).

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This study aimed to obtain a high yield and purity of Sargassum pallidum polyphenol extracts (SPPE) and study its enzyme activity. Fresh Sargassum pallidum seaweed was selected for optimization of ultrasound-assisted extraction (UAE) conditions and purification conditions using macroporous resin and Sephadex LH20 to obtain SPPE. The SPPE was characterized using UPLC-QTOF-MS/MS and α-amylase, α-glucosidase, tyrosinase, and AchE inhibitory activity were determined.

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The utilization of Co-Cr-Fe-based black pigments bears considerable significance within the realm of commercial ceramic pigments, owing to their distinctive spinel structure, remarkable high-temperature stability, and exceptional chromatic attributes. This study delves into the synthesis of diverse black pigment configurations by employing the co-precipitation method, leveraging the interplay of these three metallic oxides. This investigation encompasses a comprehensive scrutiny of ion valences, crystal structures and parameters, colorimetric properties, and their interrelationships.

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Owing to their biocompatibility, chemical stability, film-forming ability, cost-effectiveness, and excellent electroactive properties, poly(vinylidene fluoride) (PVDF) and PVDF-based polymers are widely used in sensors, actuators, energy harvesters, etc. In this review, the recent research progress on the PVDF phase structures and identification of different phases is outlined. Several approaches for obtaining the electroactive phase of PVDF and preparing PVDF-based nanocomposites are described.

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Chromatography combined with mass spectrometry is the most commonly used detection technology, and it offers the advantages of high sensitivity and high selectivity. The quick, easy, inexpensive, effective, rugged, and safe (QuEChERS) method is low-cost, effective, and time efficient. The application of the QuEChERS has now been extended to the analysis of contaminants in food samples.

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The intercalation properties of graphite oxide are important; however, the specific processes and mechanisms associated with intercalation have rarely been elucidated. In this paper, two types of surfactants, polyvinylpyrrolidone and tetradecyltrimethylammonium bromide, were used to thoroughly explore the intercalation properties of graphite oxide. The polyvinylpyrrolidone and tetradecyltrimethylammonium bromide-intercalated graphite oxide composites were synthesized under different conditions and characterized by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, X-ray energy dispersive spectroscopy, and transmission electron microscopy.

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Article Synopsis
  • The study investigates the impact of a specific genetic variation (TLR8 rs3764880 polymorphism) on the risk of ischemic stroke (IS) and its relationship with inflammation and lipid metabolism in a Han Chinese population.
  • Findings showed that male carriers of the G allele had higher levels of IL-8 and increased levels of total cholesterol (TC) and LDL, suggesting a link between this genetic variant and inflammation and lipid profiles in IS.
  • In contrast, no significant associations were observed in female patients regarding the TLR8 rs3764880 polymorphism, highlighting potential gender differences in genetic influence on stroke risk.
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Stroke is a multi-factorial disorder that has become the leading cause of death and disability worldwide. Previous studies reported that TLR7 mRNA expression is associated with poor outcome of ischemic stroke (IS). This study aimed to assess whether TLR7 mRNA expression affects IS occurrence, as well as the association of TLR7 rs2897827 with susceptibility to IS and TLR7 mRNA expression and serum apolipoprotein and lipid levels in a Chinese Han population.

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Many studies reported that toll-like receptors (TLRs) played an important role in the process of ischemic stroke (IS). However, the impact of TLR5 rs5744174 on stroke risk, gene expression and on inflammatory cytokines, and lipid levels in ischemic stroke patients has not yet been reported and was therefore the subject of this study. In this case-control study, a total of 816 ischemic stroke patients and 816 healthy controls were genotyped using Sequenom MassArray technology.

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Background: Stroke is a multi-factorial disorder and has become the leading cause of death and disability worldwide. Recent genome-wide association studies (GWAS) have identified a significant association of single-nucleotide polymorphism (SNP) rs2107595 in HDAC9 gene with large-vessel ischaemic stroke (IS) in the European populations. The aim of this study is to examine the association of HDAC9 gene rs2107595 polymorphism with the susceptibility of IS in southern Han Chinese.

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Background: The common and major pathological change in ischemic stroke is atherosclerosis in the artery. Tumor necrosis factor-a (TNF-a) is closely related to the pathogenesis of atherosclerosis. The aim of our study was to investigate whether TNF-a gene variants (-238G/A and -308G/A) are associated with ischemic stroke.

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Article Synopsis
  • * A meta-analysis consolidating data from 38 studies and over 8,700 participants found a significant association between the C3435T polymorphism and drug resistance, particularly in specific subgroups like Caucasian adults.
  • * The findings suggest that the ABCB1-C3435T polymorphism could be a risk factor for resistance to antiepileptic drugs, highlighting the need for more research to confirm these results.
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A superhydrophobic polypropylene (PP) coating on the surface of aluminum alloy coupons is unstable because of the existence of metastable state in curing process. Nano-titania particles were added into PP solution to form hierarchical micro- and nano-structures of PP coatings on the surface of aluminum alloy coupons. The morphology of the coatings was observed with Scanning Electron Microscopy (SEM), and the corresponding structure and components were investigated with Energy Dispersive Spectrometer (EDS) and X-ray diffractometer (XRD), respectively.

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Article Synopsis
  • The study investigates the relationship between DAOA gene polymorphisms and the risk of schizophrenia, bipolar disorder, and depressive disorder, as previous research showed conflicting results.
  • A meta-analysis incorporating 46 studies with over 17,000 cases was conducted to evaluate whether specific DAOA SNPs were linked to these psychiatric conditions.
  • The findings indicate that the DAOA variants M15, M18, and M23 do not significantly increase the risk of developing schizophrenia, bipolar disorder, or depressive disorder, but more research is needed for conclusive results.
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A simple and novel approach has been developed to obtain a microporous film with compound nanoparticles on the surface of aluminum alloy substrate using the galvanic corrosion method. The wettability of the surface changes from hydrophilicity to superhydrophobicity after chemical modification with stearic acid (SA). The water contact angle (WCA) and sliding angle (WSA) of superhydrophobic aluminum alloy surface (SAAS) are 154 degrees and 9 degrees, respectively.

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