Publications by authors named "Haiyu Han"

Tibetan donkeys inhabit the harsh environment of the Qinghai-Tibet Plateau. Research on serum metabolites related to their high-altitude adaptation is limited compared to other livestock. We used liquid chromatography-mass spectrometry (LC-MS) to analyze serum samples from healthy adult donkeys in Shigatse, Changdu, and Dezhou to evaluate the effects of high altitudes on serum metabolites.

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Article Synopsis
  • The Qinghai-Tibet Plateau hosts Tibetan pigs, which have undergone adaptive evolution for high-altitude living, making them a significant genetic resource.
  • A study analyzed 348 genetic datasets, identifying 4,598 SNPs and 131 candidate genes linked to high-altitude adaptation, particularly in heart function and hemoglobin levels.
  • Key genes like CLEC17A were noted for their roles in adaptation, providing valuable insights and resources for future research on Tibetan pigs and their genetics.
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In recent years, the three-way crossbred commercial pigs are extensively cultured in Tibet. However, there have been few studies about the effect of high-altitude hypoxic environment on intestinal health of them. Therefore, we selected Tibetan pigs (TP) and the three-way crossbred commercial pigs (CP-H) living in the Tibet (3,500-3,700 m in altitude) as a positive control group and treatment group, respectively.

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