Publications by authors named "Haiyang Xiao"
Article Synopsis
- This study explores the genetic differences between upper tract urothelial carcinoma (UTUC) and urothelial carcinoma of the bladder (UCB), focusing on mutations in chromatin regulatory genes and T-cell receptor diversity.
- Results showed that both UTUC and UCB have similar mutations in chromatin genes, but distinct differences in DNA damage repair mutations, tumor mutation burden, and T-cell receptor diversity, indicating varying prognoses.
- The study suggests that mutations in chromatin pathway genes could be useful as biomarkers for disease progression and potential therapeutic targets in both types of cancer.
Metastasis is the primary culprit behind cancer-related fatalities in multiple cancer types, including prostate cancer. Despite great advances, the precise mechanisms underlying prostate cancer metastasis are far from complete. By using a transgenic mouse prostate cancer model (TRAMP) with and without Phf8 knockout, we have identified a crucial role of PHF8 in prostate cancer metastasis.
View Article and Find Full Text PDFBackground: Essential genes encode functions that play a vital role in the life activities of organisms, encompassing growth, development, immune system functioning, and cell structure maintenance. Conventional experimental techniques for identifying essential genes are resource-intensive and time-consuming, and the accuracy of current machine learning models needs further enhancement. Therefore, it is crucial to develop a robust computational model to accurately predict essential genes.
View Article and Find Full Text PDFAn electronic transition-based bare bones particle swarm optimization (ETBBPSO) algorithm is proposed in this paper. The ETBBPSO is designed to present high precision results for high dimensional single-objective optimization problems. Particles in the ETBBPSO are divided into different orbits.
View Article and Find Full Text PDFA twinning bare bones particle swarm optimization(TBBPSO) algorithm is proposed in this paper. The TBBPSO is combined by two operators, the twins grouping operator (TGO) and the merger operator (MO). The TGO aims at the reorganization of the particle swarm.
View Article and Find Full Text PDFPurpose: To investigate the clinical outcomes and possible risk factors associated with rotational stability after the implantation of a V4c toric implantable Collamer lens (TICL) for the correction of moderate to high myopic astigmatism.
Methods: A total of 112 eyes of 66 patients with moderate to high myopic astigmatism underwent TICL implantation. All patients were followed up for more than 1 year.