The detection depth of current borehole acoustic reflection imaging is only tens of meters without high resolution. This considerably limits its wide application in the identification and fine description of unconventional reservoirs and in the optimization of drilling trajectories. Increasing the directional energy from the transmitter to a geological structure is an excellent way to solve this issue.
View Article and Find Full Text PDFAn on-chip supercontinuum (SC) source spanning from 900 nm to 2000 nm has been experimentally presented and analyzed based on a (GeAsS) planar waveguide at telecommunication wavelength. The nonlinear response parameter () of the GeAsS waveguide is estimated to be ∼12// at the pump wavelength using resonant grating waveguide (RGW) nonlinear refractive index (=2×10/), which is measured by the z-scan technique. The dispersion of the waveguide is carefully engineered based on the refractive index of the GeAsS film where the film structure is confirmed by a Raman spectrum exhibiting consistency with the corresponding glass.
View Article and Find Full Text PDFAims: Although the pathophysiology of amyotrophic lateral sclerosis (ALS) is still not completely understood, the deregulated microglia polarization and neuroinflammation have been shown to contribute to the pathogenesis and progression of this disease. In the present study, we aimed to determine whether hirsutella sinensis (HS) could reduce neuroinflammatory and pathological changes in the spinal cord of SOD1 model mice of ALS and consequently ameliorate disease onset and progression.
Methods: SOD1 mice were chronically treated with HS by gavage.
Cyclin-dependent kinase 1 (CDK1) is the only necessary CDK in cell proliferation and a novel target in the development of anticancer drugs. 8-Hydroxypiperidinemethyl-baicalein (BA-j) is a novel selective CDK1 inhibitor with broad spectrum anti-cancer activity (IC50 12.3 μM) and 2 tumor xenografts.
View Article and Find Full Text PDFA technique is proposed to measure the high-resolution and wide-band characterization of amplitude, phase responses, and polarization property of optical components. This technique combines the optical spectrum stitching and optical channel estimation methods. Two kinds of fiber Bragg grating based Fabry-Perot cavities with ultrafine structures have been characterized based on this technique.
View Article and Find Full Text PDFTo investigate the effects of psychological stress on the masticatory muscles of rats, a communication box was applied to induce the psychological stress (PS) in rats. The successful establishment of psychological stimulation was confirmed by elevated serum levels of adrenocorticotropic hormone (ACTH) and changed behaviors in the elevated plusmaze apparatus. The energy metabolism of the bilateral masseter muscles was tested via chemocolorimetric analysis, whereas muscle ultrastructure was assessed by electron microscopy.
View Article and Find Full Text PDF