Construction of a recombinant lentivirus-mediated shRNA expression vector targeting the human PSMD10 gene and validation of RNAi efficiency in RPMI‑8226 multiple myeloma cells.

Multiple myeloma (MM) is one of the most common malignant blood cancers. Previous studies have reported that proteasome 26S subunit non-ATPase 10 (PSMD10) is an oncoprotein with complex roles in hepatocellular carcinoma and other malignant tumors. Notably, research on the relationship between PSMD10 and tumorigenesis of MM has rarely been reported.

Diagnostic value of using 18F-FDG PET and PET/CT in immunocompetent patients with primary central nervous system lymphoma: A systematic review and meta-analysis.

Background: 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) and PET/CT have become two of the most powerful tools for malignant lymphoma exploration, but their diagnostic role in primary central nervous system lymphoma (PCNSL) is still disputed. The purpose of our study is to identify the usefulness of 18F-FDG PET and PET/CT for detecting PCNSL.

Results: A total of 129 patients, obtained from eight eligible studies, were included for this systematic review and meta-analysis.

Primary testicular lymphoma with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse: A case report and literature review.

Primary testicular lymphoma (PTL) accounts for ~1% of all non-Hodgkin's lymphomas and has a marked tendency for systemic relapse. The current study presents a unique case of testicular diffuse large B-cell lymphoma of non-germinal center B-cell subtype, with subcutaneous masses as the sole manifestation of the first relapse and central nervous system lymphoma as the second relapse. Subcutaneous relapse and subsequent brain relapse are extremely rare signs of PTL dissemination.

Predictors of return to work and duration of absence following work-related hand injury.

The aims of the study were to explore the situation and the potential determinants of return-to-work (RTW) and the absence duration following work-related hand injury, and to provide evidence for the future intervention strategy of improving RTW. A prospective cohort of workers with work-related hand injury from three selected hospitals in East China was followed up on the outcomes of RTW up to 8 months after discharge. Demographic and clinical data were collected during admission; economic factors, psychological factors and RTW outcomes were, respectively, investigated using a structured questionnaire via phone call after discharge from the hospitals in 0.

Mechanism of hydrogenation reaction in the Li-Mg-N-H system.

The Li-Mg-N-H system composed of 3 Mg(NH2)2 and 8 LiH reversibly desorbs/absorbs approximately 7 wt % of H2 at 120-200 degrees C and transforms into 4 Li2NH and Mg3N2 after dehydrogenation. In this work, the mechanism of the hydrogenation reaction from 4 Li2NH and Mg3N2 to 8 LiH and 3 Mg(NH2)2 was investigated in detail. Experimental results indicate that 4 Li2NH is first hydrogenated into 4 LiH and 4 LiNH2.

Hydrogen storage properties of Li-Mg-N-H systems with different ratios of LiH/Mg(NH2)2.

In this work, the hydrogen desorption and structural properties of the Li-Mg-N-H systems with different LiH/Mg(NH2)2 ratios are systemically investigated. The results indicate that the system with the LiH/Mg(NH2)2 ratio of 6/3 transforms into Li2NH and MgNH, and then, the mixture forms an unknown phase by a solid-solid reaction, which presumably is the ternary imide Li2Mg(NH)2; the system with the LiH/Mg(NH2)2 ratio of 8/3 transforms into 4Li2NH and Mg3N2 after releasing H2 at T < 400 degrees C; the system with the LiH/Mg(NH2)2 ratio of 12/3 transforms into 4Li3N and Mg3N2 after releasing H2 at T > 400 degrees C, where the LiMgN phase is formed by the reaction between Li3N and Mg3N2. The characteristics of the phase transformations and the thermal gas desorption behaviors in these Li-Mg-N-H systems could be reasonably explained by the ammonia mediated reaction model, irrespective of the difference in the LiH/Mg(NH2)2 ratios.