A novel strategy for spinal cord reconstruction via vascularized allogeneic spinal cord transplantation combine spinal cord fusion.

Aims: Spinal cord injuries (SCI) pose persistent challenges in clinical practice due to the secondary injury. Drawing from our experience in spinal cord fusion (SCF), we propose vascularized allogeneic spinal cord transplantation (vASCT) as a novel approach for SCI, much like organ transplantation has revolutionized organ failure treatment and vascularized composite-tissue allotransplantation has addressed limb defects.

Materials And Methods: In this study, 24 dogs were paired and underwent vASCT, with donor spinal cord grafts and polyethylene glycol (PEG) application for SCF.

Developing preclinical dog models for reconstructive severed spinal cord continuity via spinal cord fusion technique.

Background: Spinal cord injury (SCI) is a severe impairment of the central nervous system, leading to motor, sensory, and autonomic dysfunction. The present study investigates the efficacy of the polyethylene glycol (PEG)-mediated spinal cord fusion (SCF) techniques, demonstrating efficacious in various animal models with complete spinal cord transection at the T10 level. This research focuses on a comparative analysis of three SCF treatment models in beagles: spinal cord transection (SCT), vascular pedicle hemisected spinal cord transplantation (vSCT), and vascularized allograft spinal cord transplantation (vASCT) surgical model.

Partial restoration of spinal cord neural continuity via vascular pedicle hemisected spinal cord transplantation using spinal cord fusion technique.

Aims: Our team tested spinal cord fusion (SCF) using the neuroprotective agent polyethylene glycol (PEG) in different animal (mice, rats, and beagles) models with complete spinal cord transection. To further explore the application of SCF for the treatment of paraplegic patients, we developed a new clinical procedure for SCF called vascular pedicle hemisected spinal cord transplantation (vSCT) and tested this procedure in eight paraplegic participants.

Methods: Eight paraplegic participants (American Spinal Injury Association, ASIA: A) were enrolled and treated with vSCT (PEG was applied to the sites of spinal cord transplantation).

Effect of dispersant on the synthesis of cotton textile waste-based activated carbon by FeCl activation: characterization and adsorption properties.

Considering the accumulation and high consumption of activating agents, anhydrous ethanol (AE) could be used to dissolve them to improve the dispersion effect, which was an effective way of improving the practical utilization rate. In this study, FeCl was dissolved in AE and further impregnated cotton textile waste (CTW) to prepare activated carbons (ACs) by pyrolysis. Afterward, ACs prepared in optimal conditions determined by the orthogonal experiment evaluated the physicochemical properties and adsorption capacities for Cr(VI).

Fabrication of cotton textile waste-based magnetic activated carbon using FeCl activation by the Box-Behnken design: optimization and characteristics.

Cotton textile waste-based magnetic activated carbon was prepared simultaneous activation-pyrolysis using FeCl as a novel activating agent. The response surface methodology based on the Box-Behnken design method was applied to optimize the preparation parameters and predict the specific surface area of the samples. The optimal activated carbon was obtained at a mass ratio of FeCl/CTW, activation time and activation temperature of 1.

Physicochemical and adsorptive characteristics of activated carbons from waste polyester textiles utilizing MgO template method.

Activated carbons with high specific surface areas were produced, utilizing waste polyester textiles as carbon precursor by magnesium oxide (MgO) template method. Magnesium chloride (MgCl), magnesium citrate (MgCi), and MgO were employed as MgO precursors to prepare activated carbons (AC-MgCl, AC-MgCi, and AC-MgO). Thermogravimetry-differential scanning calorimetry was conducted to investigate the pore-forming mechanism, and N adsorption/desorption isotherms, XRD, SEM-EDS, TEM, FTIR and pH were achieved to analyze physicochemical characteristics of the samples.