Publications by authors named "Haixu Yan"
Article Synopsis
- The Leukemia Inhibitory Factor Receptor (LIFR) works with another protein called gp130 to help cells respond to signals that can affect cell growth and movement.
- LIFR can have different effects on tumors, sometimes helping them grow and other times making them shrink, depending on the type of tumor and how the signals are sent.
- Because LIFR is found in many cancer cells and plays a big role in how tumors develop, it might be a good target for new treatments against cancer.
Dissecting multifunctional roles of forkhead box transcription factor D1 in cancers.
Biochim Biophys Acta Rev Cancer
November 2023
As a member of the forkhead box (FOX) family of transcription factors (TF), FOXD1 has recently been implicated as a crucial regulator in a variety of human cancers. Accumulating evidence has established dysregulated and aberrant FOXD1 signaling as a prominent feature in cancer development and progression. However, there is a lack of systematic review on this topic.
View Article and Find Full Text PDFRedox imbalance is a primary cause of endothelial dysfunction (ED). Under oxidant stress, many critical proteins regulating endothelial function undergo oxidative modifications that lead to ED. Cellular levels of glutathione (GSH), the primary reducing source in cells, can significantly regulate cell function via reversible protein thiol modification.
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