Circ_0001402 knockdown suppresses the chemoresistance and development of DDP-resistant cutaneous squamous cell carcinoma cells by functioning as a ceRNA for miR-625-5p.

Cutaneous squamous cell carcinoma (CSCC) is the most common metastatic skin cancer. Circular RNAs (circRNAs) are differentially expressed in CSCC and can sequester and sponge microRNAs. GSE74758 shows that hsa_circ_0001402 (circ_0001402) is the most overexpressed circRNA in CSCC.

Effect of leptin on the growth and expression of STAT3 in yak mammary epithelial cells.

Background And Aim: Leptin (LEP) is an autocrine and paracrine factor produced by the fat pad and acinar epithelial cells of the breast. This study aimed to investigate the effects of LEP on yak mammary epithelial cells (YMECs) and the expression of STAT3. In addition, we evaluated the possible effects of prolactin (PRL) on the function of LEP.

Tazarotene/Betamethasone Dipropionate Cream in Patients with Plaque Psoriasis: Results of a Prospective, Multicenter, Observational Study.

Background: Topical agents are still the mainstay for the treatment of mild-to-moderate plaque psoriasis, in which fixed combinations play an important role. Tazarotene/betamethasone dipropionate (Taz/BD) cream is a novel fixed combination approved for treating plaque psoriasis in China, but its efficacy and safety have not been verified in a real-world environment.

Objectives: The primary objective was to investigate the efficacy and safety of Taz/BD cream in treating plaque psoriasis.

A Patient With Sporotrichosis Diagnosed By Molecular Biology Combined With Traditional Methods.

We present a case of sporotrichosis diagnosed by molecular biology combined with traditional methods. Fungal DNA was extracted from skin tissues of the patient by fungal DNA extraction kit. The PCR amplified fragments were compared on GenBank website, and the pathogenic fungi were identified.

DOA Estimation for Underwater Target by Active Detection on Virtual Time Reversal Using a Uniform Linear Array.

Aiming at addressing the problem caused by multipath effects in direction of arrival (DOA) estimation for underwater targets, a method based on the active detection on virtual time reversal (ADVTR) Capon algorithm is proposed. Unlike the conventional passive target estimation method ignoring the multipath effects but only considering the direct wave, the proposed method is closer to the actual situation in that the multipath signal propagation model is fully taken into account; in addition, active detection (AD) and virtual time reversal (VTR) processes are added, which use active detection to estimate channels, and virtual time reversal to realize focusing in a computer after the source-receive array (SRA) receives the reflected signal of the target. The combination of the two methods can greatly improve the energy of SRA and the precision of target direction estimation.