Urethral instillation of chlorhexidine gel is an effective method of sterilisation.

: To examine the effectiveness of preoperative urethral sterilisation with chlorhexidine gel in rendering the urethra as sterile as the skin of the genital area, with the skin sterilised as per the International Society for Sexual Medicine guidelines for penile prosthesis implantation. : A total of 111 male patients undergoing sterile andrological surgical procedures were divided into a control group ( = 61) and a chlorhexidine gel group ( = 50). Patients in the chlorhexidine group received urethral instillation with 6 mL of chlorhexidine preoperatively and on table.