Transaxillary vs. Transsubclavian Gasless endoscopic thyroidectomy approaches for papillary thyroid cancer.

The use of transaxillary and transsubclavian approaches for endoscopic thyroidectomy has increased globally. However, studies examining the comparative outcomes of these procedures are scarce. In this study, we aimed to compare the safety and efficacy of thyroidectomy between the gasless endoscopic thyroidectomy transaxillary approach (GETTA) and gasless endoscopic thyroidectomy transsubclavian approach (GETTSA) in patients with papillary thyroid cancer (PTC).

Feasibility of Lobectomy in Selected Patients with Unilateral N1b Papillary Thyroid Cancer.

Background: Total thyroidectomy (TT) is usually recommended for unilateral papillary thyroid cancer (PTC) with lateral lymph node metastasis (LLNM), but no significant improvement in recurrence-free survival (RFS) is seen upon treatment. As an initial surgery, lobectomy may have advantages in appropriately selected unilateral PTC with ipsilateral LLNM.

Objective: This study aimed to explore the feasibility of lobectomy for selected unilateral PTC with ipsilateral LLNM.

Inhibited Passivation by Bioinspired Cell Membrane Zn Interface for Zn-Air Batteries with Extended Temperature Adaptability.

Due to the slow dynamics of mass and charge transfer at Zn|electrolyte interface, the stable operation of Zn-air batteries (ZABs) is challenging, especially at low temperature. Herein, inspired by cell membrane, a hydrophilic-hydrophobic dual modulated Zn|electrolyte interface is constructed. This amphiphilic design enables the quasi-solid-state (QSS) ZABs to display a long-term cyclability of 180 h@50 mA cm at 25 °C.

Elucidating the effects of nitrogen and phosphorus co-doped carbon on complex spinel NiFeO towards oxygen reduction reaction in alkaline media.

The study presents for the first time complex spinel NiFeO nanoparticles supported on nitrogen and phosphorus co-doped carbon nanosheets (NPCNS) prepared using sol gel and the carbonization of graphitic carbon nitride with lecithin as a highly active and durable electrocatalyst for oxygen reduction reaction. The physicochemical properties of complex spinel NiFeO on NPCNS and subsequent nanomaterials were investigated using techniques such as X-ray diffraction, Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and transmission electron microscopy. The electrochemical activity of the electrocatalysts was evaluated using hydrodynamic linear sweep voltammetry, cyclic voltammetry, electrochemical impedance spectroscopy, and chronoamperometry.

Indium oxide with oxygen vacancies boosts O adsorption and activation for electrocatalytic HO production.

Oxygen reduction reaction the two-electron pathway (2e ORR) offers a sustainable opportunity for hydrogen peroxide (HO) production, but suffers from low selectivity. In this work, indium oxide with oxygen vacancies (InO) exhibits a HO selectivity close to 98% at 0.6 V RHE.

Synergistic effect of AlO-decorated reduced graphene oxide on microstructure and mechanical properties of 6061 aluminium alloy.

In this study, Al6061 alloy matrix composites reinforced AlO-decorated reduced graphene oxide (AlO/RGO) with 0.1, 0.3 and 0.

Explaining the improving effect of dough crumb-sheet composite rolling on fresh noodle quality: From microstructure and moisture distribution perspective.

A new technique known as dough crumb-sheet composite rolling (DC-SCR) was used to improve the quality of fresh noodles. However, there is a dearth of theoretical investigations into the optimal selection of specific parameters for this technology, and the underlying mechanisms are not fully understood. Therefore, the effects of dough crumb addition times in DC-SCR on the texture, cooking, and eating quality of fresh noodles were first studied.

Anomaly Detection of Permanent Magnet Synchronous Motor Based on Improved DWT-CNN Multi-Current Fusion.

The Permanent Magnet Synchronous Motor (PMSM) is the power source maintaining the stable and efficient operation of various pieces of equipment; hence, its reliability is crucial to the safety of public equipment. Convolutional Neural Network (CNN) models face challenges in extracting features from PMSM current data. A new Discrete Wavelet Transform Convolutional Neural Networks (DW-CNN) feature with fusion weight updating Long Short-Term Memory (LSTM) anomaly detection is proposed in this paper.

Highly Reversible Zn-Air Batteries Enabled by Tuned Valence Electron and Steric Hindrance on Atomic Fe-N-C Sites.

The bifunctional oxygen electrocatalyst is the Achilles' heel of achieving robust reversible Zn-air batteries (ZABs). Herein, durable bifunctional oxygen electrocatalysis in alkaline media is realized on atomic Fe-N-C sites reinforced by NiCoO (NiCoO@Fe/NC). Compared with that of pristine Fe/NC, the stability of the oxygen evolution reaction (OER) is increased 10 times and the oxygen reduction reaction (ORR) performance is also improved.

Folding during sheeting improved qualities of dried noodles through gluten network proteins.

The texture properties after cooking for 12 min were selected to optimize the sheeting parameters, and the results were verified using the comprehensive quality of dried noodles. The distribution of water, characteristics of gluten protein, and interaction between gluten network and starch were analyzed to clarify the mechanism of the quality of dried noodles. Results showed that the optimal folding angle was 45°, under this condition, the largest anti-extension displacement perpendicular to the rolling direction and the smallest cooking loss were obtained.

Dark-field imaging and fluorescence dual-mode detection of microRNA-21 in living cells by core-satellite plasmonic nanoprobes.

The in situ precise quantification and simultaneous imaging of low abundance microRNAs (miRNAs) within living cells is critical for cancer diagnosis, yet it remains a significant challenge. Leveraging the excellent sensitivity and spatiotemporal resolution of dark-field microscopy (DFM) and fluorescence imaging, we have successfully devised a novel detection approach using dual-signal reporter probes (DSRPs). These probes allow for highly sensitive detection of miRNA-21 in living cells via toehold-mediated strand displacement cascades.

Tanshinone IIA alleviates bleomycin-induced pulmonary fibrosis by inhibiting Zbtb16.

Pulmonary fibrosis is a complex disease that can occur in a variety of clinical settings. The Zinc Finger and BTB Domain Containing 16 (Zbtb16) is a transcription factor and has not been studied in pulmonary fibrosis. Lung tissues from rats which were treated with bleomycin and Tanshinone IIA (Tan IIA) were collected for mRNA sequencing.

Gasless Single-Incision Endoscopic Surgery via Subclavicular Approach for Lateral Neck Dissection in Patients with Papillary Thyroid Cancer.

Background: The technical difficulties and trauma of remote access methods in endoscopic surgery (ES) for lateral neck dissection (LND) can be daunting for most patients with papillary thyroid cancer (PTC) and surgeons. The purpose of study was to introduce gasless single-incision ES via a subclavicular approach (ESSA) and to explore its safety and efficacy for LND.

Methods: Between January 2022 and February 2023, we retrospectively reviewed 17 patients with PTC who underwent ESSA for LND.

A novel cuproptosis-related lncRNA prognostic signature in thyroid cancer.

We aimed to investigate the value of cuproptosis-related lncRNA in screening out high-risk thyroid cancer patients. RNA sequencing data of thyroid cancer were obtained from The Cancer Genome Atlas. A cuproptosis-related lncRNA signature was constructed by using Cox regression.

Risk stratification of papillary thyroid cancers using multidimensional machine learning.

Background: Papillary thyroid cancer (PTC) is one of the most common endocrine malignancies with different risk levels. However, preoperative risk assessment of PTC is still a challenge in the worldwide. Here, the authors first report a Preoperative Risk Assessment Classifier for PTC (PRAC-PTC) by multidimensional features including clinical indicators, immune indices, genetic feature, and proteomics.

Inflammatory cytokine-regulated LNCPTCTS suppresses thyroid cancer progression via enhancing Snail nuclear export.

Lymph node metastases are commonly observed in diverse malignancies where they promote cancer progression and poor outcomes, although the molecular basis is incompletely understood. Thyroid cancer is the most prevalent endocrine neoplasm characterized by high frequency of lymph node metastases. Here, we uncover an inflammatory cytokines-controlled epigenetic program during thyroid cancer progression.

Targeting hnRNPC suppresses thyroid follicular epithelial cell apoptosis and necroptosis through mA-modified ATF4 in autoimmune thyroid disease.

Both environmental and genetic factors contribute to the etiology of autoimmune thyroid disease (AITD) including Graves' disease (GD) and Hashimoto's thyroiditis (HT). However, the exact pathogenesis and interactions that occur between environmental factors and genes remain unclear, and therapeutic targets require further investigation due to limited therapeutic options. To solve such problems, this study utilized single-cell transcriptome, whole transcriptome, full-length transcriptome (Oxford nanopore technology), and metabolome sequencing to examine thyroid lesion tissues from 2 HT patients and 2 GD patients as well as healthy thyroid tissue from 1 control subject.

US of thyroid nodules: can AI-assisted diagnostic system compete with fine needle aspiration?

Objectives: Artificial intelligence (AI) systems can diagnose thyroid nodules with similar or better performance than radiologists. Little is known about how this performance compares with that achieved through fine needle aspiration (FNA). This study aims to compare the diagnostic yields of FNA cytopathology alone and combined with BRAFV600E mutation analysis and an AI diagnostic system.

Performance of CT-based deep learning in diagnostic assessment of suspicious lateral lymph nodes in papillary thyroid cancer: a prospective diagnostic study.

Background: Preoperative evaluation of the metastasis status of lateral lymph nodes (LNs) in papillary thyroid cancer is challenging. Strategies for using deep learning to diagnosis of lateral LN metastasis require additional development and testing. This study aimed to build a deep learning-based model to distinguish benign lateral LNs from metastatic lateral LNs in papillary thyroid cancer and test the model's diagnostic performance in a real-world clinical setting.

Artificial intelligence-based prediction of cervical lymph node metastasis in papillary thyroid cancer with CT.

Objectives: To develop an artificial intelligence (AI) system for predicting cervical lymph node metastasis (CLNM) preoperatively in patients with papillary thyroid cancer (PTC) based on CT images.

Methods: This multicenter retrospective study included the preoperative CT of PTC patients who were divided into the development, internal, and external test sets. The region of interest of the primary tumor was outlined manually on the CT images by a radiologist who has eight years of experience.

Pediatric hypereosinophilic syndrome associated with liver damage, portal vein, splenic vein and superior mesenteric vein thromboses: a case report.

Background: The hypereosinophilic syndrome (HES) is a group of rare blood disorders characterized by persistent eosinophilia and damage to multiple organs. HES can be either primary, secondary or idiopathic. Secondary HES are commonly caused by parasitic infections, allergic reactions or cancer.

The ambulatory transoral endoscopic thyroidectomy vestibular approach is safe and economical for patients with thyroid nodules.

Background: Ambulatory thyroid surgery has been increasingly performed in recent years. However, the feasibility of the ambulatory transoral endoscopic thyroidectomy vestibular approach (TOETVA) has not been evaluated. We aimed to evaluate the safety, economy, and mental health outcomes of ambulatory TOETVA.

Metformin and 2-Deoxy-d-glucose synergistically inhibit the viability of thyroid papillary carcinoma with BRAF mutation by ROS-dependent PI3K/AKT signaling pathway.

The aim of this study was to explore the molecular mechanism through which metformin combined with 2-deoxy-d-glucose (2-DG) decreases the viability of BCPAP thyroid papillary carcinoma cells. BCPAP cells were treated with only metformin, only 2-DG, and both metformin and 2-DG. We used the CCK-8 assay to assess cell viability, dichlorofluorescein staining to detect reactive oxygen species (ROS), and western blot analysis to quantify protein expression.

Advances in coastal ocean boundary layer detection technology and equipment in China.

Accurate and comprehensive knowledge of the atmospheric environment and its evolution within the coastal ocean boundary layer are necessary for understanding the sources, chemical mechanisms, and transport processes of air pollution in land, sea, and atmosphere. We present an overview of coastal ocean boundary layer detection technology and equipment in China and summarize the progress and main achievements in recent years. China has developed a series of coastal ocean boundary layer detection technologies, including Light Detection and Ranging (LIDAR), turbulent exchange analyzer, air-sea flux analyzer, stereoscopic remote sensing of air pollutants, and oceanic aerosol detection equipment to address the technical bottleneck caused by harsh environmental conditions in coastal ocean regions.