Publications by authors named "Haitang Qin"
Article Synopsis
- Mesenchymal stem cells (MSCs) can potentially treat osteoarthritis (OA) by regenerating cartilage, but their natural repair abilities are limited.
- Researchers engineered MSCs using circular mRNA that encodes fibroblast growth factor 18 (FGF18) and encapsulated it in a novel glycerolipid-based lipid nanoparticle (LNP) for enhanced therapeutic effects.
- In tests on OA rats, these FGF18-engineered MSCs significantly improved cartilage health and repair, showing promise for better OA treatments by overcoming the current limitations of MSC therapy.
