Publications by authors named "Haishao Xiao"
Objective: To analyze the changes in the prevalence of myopia and its relation to ocular biological parameters, and behaviors among primary school students in China, and understand the prevention and control of myopia.
Methods: Cross-sectional surveys were performed on 7-9-year-old children in the yrs. 2012 and 2019.
Clinical Relevance: Knowledge of interactions between genetic variants and near-work activities at the onset of myopia can facilitate health education regarding myopia.
Background: To investigate the interactions between genetic variants ( and ) and near-work activities in the onset of myopia in southeastern Chinese school children.
Methods: A total of 458 non-myopic, grade 1 children aged 6-7 years were included in a 4-year follow-up examination; 409 children were assessed further.
Objective: The present study was designed to investigate whether the extracellular signal-regulated kinase (ERK) signaling pathway, a downstream component of dopamine signaling, is involved in myopia among Chinese children.
Methods: During a 3.5-year follow-up, 488 primary school students were enrolled in this study.
Background: Myopia is a complex multifactorial condition which involves several overlapping signaling pathways mediated by distinct genes. This prospective cohort study evaluated the associations of two genetic variants in the TGF-β signaling pathway with the onset and progression of myopia and ocular biometric parameters in Chinese school-aged children.
Methods: A total of 556 second grade children were examined and followed up for 3.
Objective: To investigate the association between myopia progression and school entrance age among Chinese schoolchildren and to suggest a more appropriate school age.
Methods: 1,463 children aged six to nine years from Wenzhou, China, were examined and followed up for two and a half consecutive years. Their noncycloplegic refraction was measured twice each year by using an automatic refractometer; axial length (AL) and corneal radius of curvature (CRC) were tested annually by using the IOLMaster for 2.
Background: To evaluate the impact of parental myopia and outdoor time on myopia among students in Wenzhou.
Methods: We examined 1388 primary students from first grade to third grade in Wenzhou from September 2012 to March 2015. We performed noncycloplegic refractometry on each student every six months and axial length (AL) measurements every year.
Background: Myopia is a common eye disorder that is approaching epidemic proportions worldwide. A genome-wide association study identified (rs12511037), (rs13215566), and (rs12206610) as being associated with refractive error in Asian populations. The present study investigated the associations between these three genetic variants and the occurrence and development of myopia, spherical equivalent refraction (SER), axial length (AL), and corneal curvature (CC) in a cohort of southeastern Chinese schoolchildren.
View Article and Find Full Text PDFBackground: The aim of this study was to review the demographic and characteristic distribution data of serious rural pediatric eye injuries in Wenzhou and Changsha, located in Zhejiang Province in East China and Hunan Province in Central China.
Methods: This retrospective study included hospitalized pediatric patients aged < 18 years with eye injuries at the Eye Hospital of Wenzhou Medical University and Xiangya Hospital of Central South University from January 2008 to December 2017. Demographic data, injury types, injury causes, and initial and final visual acuity (VA) were recorded and analyzed.