Research Progress on Modification of Aerogels by Chemical Vapor Deposition.

Aerogels are three-dimensional nanomaterials with low thermal conductivity, low density, high specific surface area, and high porosity. They have demonstrated remarkable performance advantages in thermal insulation, catalysis, and adsorption in recent years. However, their inherent brittleness and weak skeletal structure limit their applications.

One-pot synthesis of Eu-MOFs for bioimaging and drug delivery.

Objective: The use of metal-organic framework (MOF) platforms has been a topic of growing interest in the fields of drug delivery and bioimaging. This study was designed to develop and evaluate a novel MOF-based drug and radiation delivery nanosystem.

Methods: Eu-MOFs were characterized via X-ray diffraction, scanning electronic microscopy, and FT-IR spectrometry.

Lysophosphatidylcholine promotes intercellular adhesion molecule-1 and vascular cell adhesion molecule-1 expression in human umbilical vein endothelial cells via an orphan G protein receptor 2-mediated signaling pathway.

The oxLDL-based bioactive lipid lysophosphatidylcholine (LPC) is a key regulator of physiological processes including endothelial cell adhesion marker expression. This study explored the relationship between LPC and the human umbilical vein endothelial cell expression of intercellular adhesion molecule-1 (ICAM-1) and vascular cell adhesion molecule-1 (VCAM-1) with a particular focus on the regulation of the LPC-G2A-ICAM-1/VCAM-1 pathway in this context. We explored the LPC-inducible role of orphan G protein receptor 2 (G2A) in associated regulatory processes by using human kidney epithelial (HEK293) cells that had been transfected with pET-G2A, human umbilical vein endothelial cells (HUVECs) in which an shRNA was used to knock down G2A, and western blotting and qPCR assays that were used to confirm changes in gene expression.