Publications by authors named "Hairoshi Hayashi"
Development of an alternative approach for detecting botulinum neurotoxin type A in honey: Analysis of non-toxic peptides with a reference labelled protein via liquid chromatography-tandem mass spectrometry.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
August 2020
Article Synopsis
- Researchers created a specific labelled protein to detect non-toxic peptides from botulinum neurotoxin type A (BoNTA) in honey using advanced techniques like liquid chromatography-tandem mass spectrometry (LC-MS/MS).
- They employed a careful two-step process to isolate proteins from honey, ensuring effective digestion and removing interference from salts.
- The method successfully identified unique non-toxic peptides, confirming no BoNTA presence in 19 honey samples tested, highlighting its potential for improving food safety monitoring.