Publications by authors named "Haiquing Li"
Article Synopsis
- - The study explored the relationship between microsatellite instability (MSI) in colon cancers and its connection to gene expressions related to chemoresistance and DNA repair, hypothesizing that MSI tumors have a distinct gene expression profile compared to microsatellite-stable (MSS) tumors.
- - Using ultra high-throughput sequencing (UHTS), researchers analyzed gene expression in specific MSI and MSS colon cancer cell lines and a normal colonic tissue sample, focusing on 40 related genes.
- - Results showed that MSI cell lines had lower expression of mismatch repair (MMR) genes but higher expression of genes associated with chemoresistance and drug metabolism, suggesting molecular differences that may explain why MSI tumors resist chemotherapy.
