Biomechanical analysis of nickel-titanium (NiTi)-cobalt-chromium (CoCr) hybrid-braided dense-mesh stents for carotid artery stenosis.

This study investigates NiTi-CoCr hybrid carotid artery stents to enhance mechanical properties over NiTi-only designs. Different configurations (24NiTi, 20NiTi-4CoCr, 16NiTi-8CoCr, and 12NiTi-12CoCr) were evaluated through radial compression and bending simulations. The 12NiTi-12CoCr stent showed the highest radial support (39.

Simulation analysis of different types of balloon dilatation catheters for the treatment of intracranial arterial stenosis.

The application of balloon dilation catheters in the management of intracranial arterial stenosis has been gradually increasing. However, studies on the feasibility and effectiveness of different types of balloons remain relatively scarce. In this study, catheter models of three different materials were designed to simulate balloon crimping,splitting, and dilatation processes.

A data compression algorithm with the improved SRLE for high-throughput neural signal acquisition device.

Background: Multi-channel acquisition systems of brain neural signals can provide a powerful tool with a wide range of information for the clinical application of brain computer interfaces. High-throughput implantable systems are limited by size and power consumption, posing challenges to system design.

Objective: To acquire more comprehensive neural signals and wirelessly transmit high-throughput brain neural signals, a FPGA-based acquisition system for multi-channel brain nerve signals has been developed.

Viral aptamer screening and aptamer-based biosensors for virus detection: A review.

Virus-induced infectious diseases have a detrimental effect on public health and exert significant influence on the global economy. Therefore, the rapid and accurate detection of viruses is crucial for effectively preventing and diagnosing infections. Aptamer-based detection technologies have attracted researchers' attention as promising solutions.

[Design and analysis of shoulder type exoskeleton stretcher for individual soldier].

For the transportation process of rescuing wounded personnel on naval vessels, a new type of shoulder type exoskeleton stretcher for individual soldier was designed in this paper. The three-dimensional model of the shoulder type exoskeleton stretcher for individual soldier was constructed using three dimensional modeling software. Finite element analysis technique was employed to conduct statics simulation, modal analysis, and transient dynamics analysis on the designed exoskeleton stretcher.

Algae: A Robust Living Material Against Cancer.

Cancer is the second leading cause of death worldwide. Its incidence has been increasing in recent years, and it is becoming a major threat to human health. Conventional cancer treatment strategies, including surgery, chemotherapy, and radiotherapy, have faced problems such as drug resistance, toxic side effects and unsatisfactory therapeutic efficacy.

Finite element analysis of braided dense-mesh stents for carotid artery stenosis.

When braided dense-mesh stents are used to treat carotid stenosis, the structural mechanics of vascular stents, the contact mechanics with blood vessels, and the fluid mechanics in the blood environment need to be studied in depth to reduce the damage of stents to blood vessels and the incidence of in-stent restenosis. Three types of braided stents with 8, 16, and 24 strands and laser-cut stents with the corresponding size parameters were designed, and the bending behavior of each of these types of stent, deployment, and fluid dynamic analysis of the 24-strand braided stent were simulated. The results show that the bending stress of the 8-, 16-, and 24-strand braided stents is 46.

Clinical value of video-assisted single-lumen endotracheal intubation and application of artificial intelligence in it.

Visualization techniques and artificial intelligence (AI) are currently used for intubation device. By providing airway visualization during tracheal intubation, the technologies provide safe and accurate access to the trachea. The ability of AI to automatically identify airways from images of intubation device makes it attractive for use in intubation devices.

Design and evaluation of a multimodal balance training system.

Objective: Current balance training systems are designed exclusively for one particular type of training and assessment. Additionally, they comprise monotonous training programs. Therefore, patients in different stages of rehabilitation must use different balance training models from different manufacturers, resulting in high treatment cost.

[Material design and temperature field simulation analysis of tumor radiofrequency ablation needle].

To solve the problems of small one-time ablation range and easy charring of the tissue around the electrode associated with the tumor radiofrequency ablation needle, based on the multiphysical field coupling analysis software COMSOL, the effects of needle material, the number of sub needles and the bending angle of sub needles on the ablation effect of radiofrequency ablation electrode needle were studied. The results show that compared with titanium alloy and stainless steel, nickel titanium alloy has better radiofrequency energy transmission efficiency and it is the best material for electrode needle. The number of sub needles has a great influence on the average necrosis depth and the maximum necrosis diameter.

Biomechanical analysis of mandibular defect reconstruction based on a new base-fixation system.

Buccal titanium plate fixation is a common method for repairing mandibular defects. However, the method presents certain problems: the requirement of a large volume of titanium plate, a large number of fixation screws, a lengthy duration of the surgical operation, and exposure of the fixation plate which easily causes wound infection. In this study, a new base-fixation system was designed.

Finite element analysis of fixation effect for femoral neck fracture under different fixation configurations.

In this study, the biomechanical differences among three internal fixation configurations for treatment of Pauwels type II and III femoral neck fractures were analyzed. Using finite element analysis, the femur displacement and stress distributions of the internal fixation device and fracture section were obtained for different patients and movement conditions. The results show that patients with osteoporosis are more prone to femoral varus and femoral neck shortening, and the fracture probability of the device for these patients is higher than that for patients with normal bone.

Multifunctional testing system design for varicose vein therapy apparatus.

Varicose veins of lower extremity can be treated effectively with varicose vein therapy apparatus. In order to ensure its therapy effect, it is necessary to test the air tightness of pneumatic circuit and other related performance parameters. The traditional manual testing method has some problems, such as large error, low efficiency and so on.

A novel fast solving method for targeted drug-delivery capsules in the gastrointestinal tract.

Background: As an innovative technique without cable connection, targeted drug-delivery capsules improve diagnostic and therapeutic capabilities in the gastrointestinal (GI) tract.

Objective: To fast track targeted drug-delivery capsules in the GI tract, a tracking method based on the multiple alternating magnetic sources with adaptive adjustment of the excitation intensity has been investigated.

Methods: The functional prototype of the tracking system has been developed.

A novel and reproducible release mechanism for a drug-delivery system in the gastrointestinal tract.

To establish a reliable, reproducible and accurate release of the drug in the gastrointestinal tract, a novel release mechanism for a controllable drug-delivery system has been investigated. The release mechanism, consisting of a one-way valve for drug release, a drug chamber, two axially magnetized cylindrical permanent magnets and a multi-layer solenoid coil, is hosted in the capsule-shaped shell with diameter 11 mm and length 30 mm. To actuate the coil piston, the two static magnetic fields produced by the two magnets are aligned along the same axis, having the same magnitude, but opposite directions.

Safety and efficacy of a novel abluminal groove-filled biodegradable polymer sirolimus-eluting stent.

Late stent thrombosis (LST) following drug-eluting stent (DES) implantation in patients with coronary artery disease (CAD) is often associated with delayed vascular healing, resulting from vascular inflammation and hypersensitivity to durable polymers and drugs. Therefore, DES design, materials, and coatings have been technologically revolutionized. Herein, we designed a novel abluminal groove-filled biodegradable polymer sirolimus-eluting stent (AGF-BP-SES), with a sirolimus content of only about one-third of traditional DES.

[Testing system design and analysis for the execution units of anti-thrombotic device].

In an anti-thrombotic pressure circulatory device, relays and solenoid valves serve as core execution units. Thus the therapeutic efficacy and patient safety of the device will directly depend on their performance. A new type of testing system for relays and solenoid valves used in the anti-thrombotic device has been developed, which can test action response time and fatigue performance of relay and solenoid valve.

[Design of a testing system for antithrombotic pressure circulatory equipment].

A new type of testing system used for antithrombotic pressure circulatory equipment has been developed, which realized a new method for the calibration of pressure sensor. Multi-path control and acquisition functions are achieved by this method based on human-computer interaction testing system. The precision of pressure sensor is ob tained by polynomial fitting for each test point using linear interpolation method.