Publications by authors named "Hains L"
Article Synopsis
- Surgical headwear is crucial for maintaining sterility in medical settings, but there's a growing need for environmentally sustainable options to reduce the healthcare industry's ecological impact.
- A systematic review and meta-analysis assessed the safety and environmental effects of reusable surgical headwear, comparing it with disposable alternatives across multiple studies involving over 45,000 procedural cases.
- The results showed no significant difference in surgical site infection rates between reusable and disposable headwear, while reusable options had a significantly lower environmental impact, supporting a move towards more sustainable practices in healthcare.
Purpose: Podcasts are an increasingly popular medium for medical education in the field of cardiology. However, evidence suggests that the quality of the information presented can be variable. The aim of our study was to assess the quality of the most popular cardiology podcasts on existing podcast streaming services, using tools designed to grade online medical education.
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- Prehabilitation aims to enhance patients' health before surgery to improve surgical outcomes, and a systematic review was conducted to assess its effectiveness within General Surgery based on randomized controlled trials (RCTs).
- The review included 36 RCTs, mostly from Europe and North America, showing mixed results; while many physical and psychological interventions demonstrated some benefits, the evidence was insufficient for standardized implementation across the discipline.
- Although prehabilitation interventions showed variability in effectiveness, the potential benefits suggest they should be considered individually rather than as a blanket protocol across all surgical cases.
Epilepsy has many causes and comorbidities affecting as many as 4% of people in their lifetime. Both idiopathic and symptomatic epilepsies are highly heritable, but genetic factors are difficult to characterize among humans due to complex disease etiologies. Rodent genetic studies have been critical to the discovery of seizure susceptibility loci, including mutations identified in both mouse and human cohorts.
View Article and Find Full Text PDFBackground: Neurochemical monitoring via sampling probes is valuable for deciphering neurotransmission in vivo. Microdialysis is commonly used; however, the spatial resolution is poor.
New Method: Recently push-pull perfusion at low flow rates (50nL/min) has been proposed as a method for in vivo sampling from the central nervous system.
Stimulating sensitized immune cells with a subsequent immune challenge results in potentiated pro-inflammatory responses translating into exacerbated sickness responses (i.e. fever, pain and lethargy).
View Article and Find Full Text PDFUnlabelled: Activation of spinal microglia and consequent release of proinflammatory mediators facilitate pain. Under certain conditions, responses of activated microglia can become enhanced. Enhanced microglial production of proinflammatory products may result from priming (sensitization), similar to macrophage priming.
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