Non-completion of latent tuberculosis infection treatment among Vietnamese immigrants in Southern California: A retrospective study.

Objectives: To examine socio-demographic and health-related factors associated with latent tuberculosis infection (LTBI) treatment refusal, non-initiation, and non-completion among a cohort of Vietnamese immigrants.

Design: This is a retrospective cohort study in which LTBI charts were reviewed at a public health clinic in Orange County, California between January 2010 and August 2011.

Sample: Altogether, 474 patient charts with documented LTBI treatment were reviewed for patients who met the inclusion criteria.

Management of latent tuberculosis infection in child contacts of multidrug-resistant tuberculosis.

After exposure to a teacher with multidrug-resistant pulmonary tuberculosis, 31 children developed latent infection. Twenty-six were treated with levofloxacin and pyrazinamide. Twelve required a change in therapy secondary to adverse effects.