Comparison of surgical efficacy between direct anterior approach and posterolateral approach in the treatment of sarcopenia with femoral neck fractures.

Background: Femoral neck fracture (FNF) is a prevalent injury among the elderly, associated with significant morbidity and mortality. Total joint arthroplasty (TJA) has markedly enhanced the quality of life for many patients; however, the benefits of the direct anterior approach (DAA), which has gained popularity in recent years, remain a subject of debate. Sarcopenia frequently occurs in patients with FNF and is linked to adverse surgical outcomes.

Identification and validation of differentially expressed disulfidptosis-related genes in hypertrophic cardiomyopathy.

Hypertrophic cardiomyopathy (HCM) is one of the most common cardiovascular diseases with no effective treatment due to its complex pathogenesis. A novel cell death, disulfidptosis, has been extensively studied in the cancer field but rarely in cardiovascular diseases. This study revealed the potential relationship between disulfidptosis and hypertrophic cardiomyopathy and put forward a predictive model containing disulfidptosis-associated genes (DRGs) of GYS1, MYH10, PDMIL1, SLC3A2, CAPZB, showing excellent performance by SVM machine learning model.

Extremely low-frequency electromagnetic fields targeting spleen modifies the populations of immunocytes in the spleen.

Our study focused on investigating the bioeffects of extremely low-frequency electromagnetic fields (ELF-EMFs) on the immune function of the spleen. We designed an electromagnetic instrument that can locally target on spleen, the spleens of mice were locally exposed to the ELF-EMF (50 Hz, 30 mT) for 14 days (4 h/day). Parallelly, the isolated splenic T cells were exposed to ELF-EMF (50 Hz, 15 mT) for 2 h.

The Mla pathway promotes re-expansion from stationary phase.

Bacteria have evolved diverse strategies to ensure survival under nutrient-limited conditions, where rapid energy generation is not achievable. Here, we performed a transposon insertion site sequencing loss-of-function screen to identify genes that promote the pathogen's fitness in stationary phase. We discovered that the Mla (maintenance of lipid asymmetry) pathway, which is crucial for transferring phospholipids from the outer to the inner membrane, is critical for stationary phase fitness.

Wide-field imaging and recognition through cascaded complex scattering media.

Considering the obvious application value in the field of minimally invasive and non-destructive clinical healthcare, we explore the challenge of wide-field imaging and recognition through cascaded complex scattering media, a topic that has been less researched, by realizing wide-field imaging and pathological screening through multimode fibers (MMF) and turbid media. To address the challenge of extracting features from chaotic and globally correlated speckles formed by transmitting images through cascaded complex scattering media, we establish a deep learning approach based on SMixerNet. By efficiently using the parameter-free matrix transposition, SMixerNet achieves a broad receptive field with less inductive bias through concise multi-layer perceptron (MLP).

Evidence of horizontal gene transfer and environmental selection impacting antibiotic resistance evolution in soil-dwelling Listeria.

Soil is an important reservoir of antibiotic resistance genes (ARGs) and understanding how corresponding environmental changes influence their emergence, evolution, and spread is crucial. The soil-dwelling bacterial genus Listeria, including L. monocytogenes, the causative agent of listeriosis, serves as a key model for establishing this understanding.

Unveiling reflectance spectral characteristics of floating plastics across varying coverages: insights and retrieval model.

Marine floating debris, particularly chemically stable plastics, poses a significant global environmental concern. These materials, due to their prevalence and durability, linger on the ocean surface for extended durations, inflicting considerable harm on marine ecosystems, life, and the food chain. The traditional methodology for investigating marine floating debris mainly uses field observations, which are time-consuming, laborious, and constrained in observational scope.

Prevention and Control of Biofouling Coatings in : A Review of Research Progress and Strategies.

The increasing environmental concerns of conventional antifouling coatings have led to the exploration of novel and sustainable solutions to address the biofouling caused by . As a rapidly expanding invasive species, the fouling process of is closely associated with microbial fouling, posing significant threats to the integrity of aquatic infrastructure and biodiversity. This review discusses recent progress in the development of non-toxic, eco-friendly antifouling coatings that are designed to effectively resist biofouling without using toxic chemicals.

Effect of legume proteins on the structure and digestibility of wheat starch-lauric acid complexes.

The effect of legume proteins (soy protein (SP), chickpea protein (CP) and peanut protein (PP)) on the properties of wheat starch-lauric acid (WS-LA) system and its intrinsic mechanism were investigated. RVA, digestion experiment and TGA results showed that legume proteins prompted the viscosity peak formation during cooling stage and increased anti-digestion and thermal stability of WS-LA system. FT-IR, Raman, XRD and C NMR results indicated that legume proteins improved the long-range and short-range ordering degree and single-helix structure of WS-LA system.

CCRR regulate MYZAP-PKP2-Nav1.5 signaling pathway in atrial fibrillation following myocardial infarction.

Atrial fibrillation (AF) is the most common sustained arrhythmia which brings a heavy burden to the lives and health of patients worldwide. Our earlier research documented cardiac conduction regulatory RNA (CCRR) as an antiarrhythmic lncRNA in heart failure. Here, we report that CCRR was decreased in atrial tissue after MI, MYZAP, and Nav1.

Ocean-scale patterns of environment and climate changes driving global marine phytoplankton biomass dynamics.

Effects of marine environment and climate changes on phytoplankton dynamics in global oceans have received increasing attention but remain a mystery. This study used a comprehensive approach combining correlation and information flow to explore relationships among phytoplankton biomass, marine environment, and climate forcing based on global observations over the past multi-decadal period. Correlation and causality between phytoplankton biomass and environmental factors exhibit spatial asymmetry-regions where environmental factors directly drive biomass variations were concentrated in oceanic currents and subtropical circulations.

Serum lncRNA RAMP2-AS1 Served as a Biomarker of Deep Vein Thrombosis Occurrence and Development in Elderly.

The incidence of deep vein thrombosis (DVT) is increasing with aging, which needs a screening and monitoring biomarker. This study focused on the significance of aging- and angiogenesis-related lncRNA RAMP2-AS1 (RAMP2-AS1) aiming to identify a promising biomarker for the incidence of DVT. Serum samples were collected from 63 healthy individuals and 98 patients with DVT.

Mouse enteric neurons control intestinal plasmacytoid dendritic cell function via serotonin-HTR7 signaling.

Serotonergic neurons in the central nervous system control behavior and mood, but knowledge of the roles of serotonergic circuits in the regulation of immune homeostasis is limited. Here, we employ mouse genetics to investigate the functions of enteric serotonergic neurons in the control of immune responses and find that these circuits regulate IgA induction and boost host defense against oral, but not systemic Salmonella Typhimurium infection. Enteric serotonergic neurons promote gut-homing, retention and activation of intestinal plasmacytoid dendritic cells (pDC).

Lipid biomarkers indicate the dynamics of particulate organic carbon and its carbon sequestration effects during the degradation of Ulva prolifera.

Millions of tons of Ulva prolifera sink to the seafloor and gradually degrade after green tide occurred annually in the Yellow Sea, releasing substantial amounts of particulate organic carbon (POC) into marine environments. However, monitoring the dynamics of macroalgae-derived POC and its carbon sequestration effects is challenging due to severe environmental disturbances. Here, we conducted a long-term simulated degradation experiment with U.

Genome-Wide Characterization of the () Zinc Finger Gene Family in and the Functional Analysis of in Shoot Gravitropism.

The plant-specific transcription factors (TFs) are vital for regulating plant growth and developmental processes. However, the characteristics and biological roles of the gene family in tomato () are still largely unexplored. In this study, 17 genes were identified in the tomato genome and classified into seven subgroups according to the evolutionary relationships of IDD proteins.