Effects of different orthokeratology lens designs on slowing axial length elongation in children with myopia.

Aim: To elucidate whether differences exist in the impact on retarding the elongation of axial length (AL) among children with myopia when utilizing orthokeratology (ortho-k) lenses employing the corneal refractive therapy (CRT) design versus those employing the vision shaping treatment (VST) design.

Methods: This retrospective clinical trial aimed to collect and analyze AL data from individuals who wore ortho-k lenses for three years. A total of 654 subjects were enrolled and prescribed one of the three specific brands of ortho-k lenses: CRT, Euclid, and Mouldway.

Repeatability and agreement of AOCT-1000 M, RTVue XR and IOL master 500 in measuring corneal thickness mapping and axial length applying principle of optical coherence tomography.

Purpose: To evaluate the repeatability and agreement of Fourier-domain optical coherence tomography (AOCT-1000 M and RTVue XR) and partial coherence interferometry biometer (IOL Master 500) in measuring corneal thickness mapping and axial length respectively.

Methods: Corneal thickness was measured by AOCT-1000 M and RTVue XR. Axial lengths were measured by AOCT-1000 M and IOL Master 500.

Is Orthokeratology Treatment Zone Decentration Effective and Safe in Controlling Myopic Progression?

Objective: To compare the myopia control efficacy and safety of decentered versus centered positioning of orthokeratology.

Methods: This is a retrospective intrasubject study, including 46 children with myopia (25 boys, 21 girls; age 11.12±0.

Assessment of patient compliance in orthokeratology and analysis of influencing factors: a cross-sectional study.

Background: Patient non-compliance, that is, failure to perform standard wear and care orthokeratology (ortho-k) lenses procedures, has been shown to be a major risk factor for contact lens-associated complications. Therefore, this study aimed to investigate the compliance with wear and care behaviors of ortho-k patients and analyze its influencing factors.

Methods: Patients who were successfully prescribed ortho-k lenses at the Eye Center of the Second Affiliated Hospital of Zhejiang University School of Medicine (ECSAHZU) were enrolled in the study.

The safety of orthokeratology in myopic children and analysis of related factors.

Objective: To evaluate the safety of overnight orthokeratology (OK) wear and explore whether factors such as age, refraction and allergic conjunctivitis (AC) history were associated with corneal adverse events (AEs) incidence.

Methods: Medical records of consecutive patients who started OK for myopia correction and continued for more than one year were retrospectively reviewed. Clinical data including sex, baseline age, spherical equivalent refraction (SER), and related medical histories were retrieved.

Kayser-Fleischer ring with keratoconus: a coincidence? A case report.

Background: It is rare for hepatolenticular degeneration [Wilson's disease (WD)] to occur along with keratoconus (KC). In our report, a teenager was diagnosed with WD because of the discovery of Kayser-Fleischer (KF) ring in the cornea, and concomitant KC was found.

Case Presentation: A 19-year-old male was diagnosed with KC due to a rapid decline in visual acuity within a short period of time.

Is It Possible to Predict Progression of Childhood Myopia Using Short-Term Axial Change After Orthokeratology?

Objectives: To investigate changes in axial length in children undergoing orthokeratology (OK) and evaluate short-term axial change in predicting post-OK myopia progression.

Methods: In this retrospective study, the subjects included 70 myopic children aged 8 to 15 years wearing OK contact lenses for more than 3 years. Axial length changes at 0.

Changes of corneal tomography in patients with congenital blepharoptosis.

The study aimed to evaluate the effect of drooped eyelid on corneal tomography in congenital blepharoptosis patients. Sixty-four patients with congenital blepharoptosis and 64 age- and sex- matched healthy subjects were included. According to the eyelid margin to corneal light reflex distance (MRD), eyes with congenital blepharoptosis were categorized as mild, moderate, or severe.

High glucose may decrease the innate immune through TLRs in cornea epithelium.

Purpose: The purpose of this study was to investigate the high potential of glucose in inhibiting the innate immune in cultured human cornea epithelial cells (HCEC) and try to determine whether the role of high glucose on the HCEC relate to toll-like receptor (TLR)2 and TLR4.

Methods: Cells were cultured for 3 days in 5 mmol/l (normal glucose). Then high glucose (25 mmol/l) was added along with normal glucose with daily changes in media for 24 h.

[Conductive keratoplasty for presbyopia and two years follow-up].

Objective: To investigate the effect of conductive keratoplasty (CK) for presbyopia and 2 years follow-up.

Methods: This study is prospective clinical trial. CK was performed on 34 patients for presbyopia, in which 26 hyperopic patients underwent binocular operations and 8 emmetropic patients underwent monocular operation.

[Advances in surgical management of presbyopia].

Presbyopia is age-related reduction in amplitude of accommodation and can not read comfortably. Current methods such as single-focus glasses, bifocal glasses and progressive additional lens are the most widely used for correction of presbyopia. All surgical solutions for presbyopia do not improve the physiological amplitude of accommodation.

[A preliminary study on development of human visual system in fetus by DiI-tracing].

Objective: To reveal the morphological features and dynamic processes of the development of inter-connections in the retina, lateral geniculate nucleus (LGN), superior colliculus (SC) and visual cortex (VC) in human fetal life by using a fluorescent tracer, 1, 1'-dioctadecyl-3, 3, 3', 3'-tetramethylin-docarbocyanine perchlorate (DiI).

Methods: DiI was embedded into the optic tract, brachium of superior colliculus and subplate of visual cortex in fixed postmortem human tissues of 7 fetuses. The tissue was incubated at 37 degrees C for 4 to 10 weeks (ws).