[Mortality and cause of death of hospitalized neonates in Weifang, China: a multicenter study].

Objectives: To study the changes in the mortality rate and cause of death of hospitalized neonates in grade A tertiary hospitals in Weifang City of Shandong Province during a 10-year period.

Methods: A retrospective analysis was performed on 461 neonates who died in three grade A tertiary hospitals in Weifang City of Shandong Province from January 1, 2012 to December 31, 2021. The related clinical data were collected to examine the changes of neonatal mortality with time, gestational age (GA) and birth weight (BW).

Application of intervention of information motivation behavior skill (IMB) model in the cardiac rehabilitation of patients with coronary heart disease.

Objectives: To explore the effects of information motivation behavior skill (IMB) model in the cardiac rehabilitation of patients with coronary heart disease.

Methods: We analyzed data from medical records of patients with coronary heart disease who had received cardiac rehabilitation treatment in the Department of Cardiology of our hospital from April 2019 to May 2021. Data from 52 patients who had received routine nursing rehabilitation (Mode-I) and 56 patients that received IMB model-oriented nursing rehabilitation (Mode-II) was included.

Effect of hope therapy on fertility stress and pregnancy rate in infertile patients undergoing intrauterine insemination.

Objective: To investigate the efficacy of hope therapy on fertility stress and pregnancy rate in infertile patients undergoing intrauterine insemination (IUI).

Methods: In this retrospective study, 180 infertile patients undergoing IUI during May 2017 and October 2019 were enrolled and grouped into a study group (n=90) receiving hope therapy and control group (n=90) receiving routine infertility care. The two groups were compared in terms of anxiety and depression, scores of Fertility Problem Inventory (FPI), scores of coping style, social support before and after intervention, and post-intervention hormone levels.

The effects of comprehensive nursing intervention on the negative emotions of patients with infertility.

Objective: To investigate the effects of comprehensive nursing intervention (CNI) on the negative emotions of patients with infertility.

Methods: A total of 132 patients were recruited as the study cohort and randomly divided into an observation group (n=62) and a control group (n=70). The patients in both groups underwent routine treatment and nursing.

CircASXL1 Knockdown Restrains Hypoxia-Induced DDP Resistance and NSCLC Progression by Sponging miR-206.

Background: Non-small cell lung carcinoma (NSCLC) is a primary prevalent type of cancer in people worldwide. Cisplatin (DDP) has been widely used to treat NSCLC; however, its curative effect was restrained under hypoxia. In this study, the effects of hypoxia treatment on DDP resistance and NSCLC progression and underneath mechanism were revealed.

Matrine Regulates Proliferation, Apoptosis, Cell Cycle, Migration, and Invasion of Non-Small Cell Lung Cancer Cells Through the circFUT8/miR-944/YES1 Axis.

Background: Non-small cell lung carcinoma (NSCLC) is the major histological subtype of cancer cases. In the present study, we investigated the association between Matrine, an active component of Chinese medicine, and circFUT8 in NSCLC cells.

Methods: The proliferation ability of NSCLC cells was assessed by MTT and colony-forming assays.

MiR-194-5p serves as a potential biomarker and regulates the proliferation and apoptosis of hippocampus neuron in children with temporal lobe epilepsy.

Background: The aim of the present study is to explore the expression level and the clinical significance of miR-194-5p to the children with temporal lobe epilepsy, and investigate its functions in regulating cell behaviors of hippocampal neurons.

Methods: The expression level of miR-194-5p was detected in the serum of 59 temporal lobe epilepsy (TLE) children and 63 healthy children. To further study the role of miR-194-5p in the development of TLE in children, the epileptiform discharge model was established in rat hippocampal neurons to mimic TLE conditions in children.

Circular RNA circ_0005774 contributes to proliferation and suppresses apoptosis of acute myeloid leukemia cells via circ_0005774/miR-192-5p/ULK1 ceRNA pathway.

Circular RNAs (circRNAs) and microRNAs (miRNAs) have been emerging as new players in acute myeloid leukemia (AML). Hsa_circ_0005774 (circ_0005774) is an upregulated circRNA in pediatric AML, while its role is uncovered. Thus, we intended to measure the function and mechanism of circ_0005774 in AML leukemogenesis.

Pneumatic separation for crushed spent lithium-ion batteries.

Pneumatic separation was used to separate the valuable current collectors and harmful separators in spent lithium-ion batteries (LIBs) to avoid the plastic pollution caused by the separators in this study. Theoretical calculations for suspension velocities of the current collectors and separators indicate that they could be separated under special conditions. Furthermore, a special Z-shaped pneumatic separator was used to separate the current collectors and separators for the first time.

Circ_0085296 suppresses trophoblast cell proliferation, invasion, and migration via modulating miR-144/E-cadherin axis.

Background: Circular RNAs (circRNAs) have been revealed to be important regulators in the biological behavior of cells, and aberrant circRNAs may be associated with the etiology of pre-eclampsia (PE). However, the role and underlying molecular mechanisms of circ_0085296 in PE remain unclear.

Methods: The expression of circ_0085296, microRNA (miR)-144, and E-cadherin was detected using quantitative real-time polymerase chain reaction and western blot, respectively.

Icariin sustains the proliferation and differentiation of Aβ-treated hippocampal neural stem cells via the BDNF-TrkB-ERK/Akt signaling pathway.

Objectives: Icariin (ICA) can be potentially used to treat Alzheimer's disease (AD), but the mechanism was not clear. The current study explored the effects of ICA on hippocampal neural stem cells, aiming to provide a comprehensive basis for its clinical application.

Methods: Hippocampal neural stem cells were isolated from newborn rats and their differentiation ability was evaluated by performing immunofluorescence staining.

Antagonizing effect of icaritin on apoptosis and injury of hippocampal neurocytes induced by amyloid beta GR/BDNF signaling pathway.

Amyloid beta is the main component of senile plaques deposited in the hippocampus of people with Alzheimer's disease (AD), with neurotoxicity and pro-apoptotic characteristics. Icaritin (ICA) has been found to have the properties of plerosis, regeneration, and anti-apoptosis in the neurocytes, its effects on Aβ-induced hippocampal neurocytes were studied in this research. Different concentrations of Aβ were used to treat mouse hippocampal neuron HT22 cells to determine the optimal concentration for constructing AD model; different concentrations of ICA were used to pretreat HT22 cells to explore their effects on cell activity.

Investigating Random Linear Coding from a Pricing Perspective.

In this paper, we study the implications of using a form of network coding known as Random Linear Coding (RLC) for unicast communications from an economic perspective by investigating a simple scenario, in which several network nodes, the users, download files from the Internet via another network node, the sender, and the receivers as users pay a certain price to the sender for this service. The mean packet delay for a transmission scheme with RLC is analyzed and applied into an optimal pricing model to characterize the optimal admission rate, price and revenue. The simulation results show that RLC achieves better performance in terms of both mean packet delay and revenue compared to the basic retransmission scheme.

[Risk factors for elevated serum total bile acid in preterm infants].

Objective: To study the risk factors for elevated serum total bile acid (TBA) in preterm infants.

Methods: A retrospective analysis was performed for the clinical data of 216 preterm infants who were admitted to the neonatal intensive care unit. According to the presence or absence of elevated TBA (TBA >24.

[Diagnostic value and influencing factors for amplitude-integrated EEG in brain injury in preterm infants].

Objective: To study the diagnostic value and influencing factors for amplitude-integrated EEG (aEEG) in brain injury in preterm infants.

Methods: One hundred and sixteen preterm infants with a gestational age (GA) between 27 weeks and 36(+6) weeks were enrolled as subjects. The aEEG scores of all preterm infants were obtained within 6 hours after birth.

Enhancing blue luminescence from Ce-doped ZnO nanophosphor by Li doping.

Unlabelled: Undoped ZnO, Ce-doped ZnO, and (Li, Ce)-codoped ZnO nanophosphors were prepared by a sol-gel process. The effects of the additional doping with Li ions on the crystal structure, particle morphology, and luminescence properties of Ce-doped ZnO were investigated by X-ray diffraction, scanning electron microscopy, X-ray photoelectron spectroscopy, electron paramagnetic resonance spectroscopy and photoluminescence spectroscopy. The results indicate that the obtained samples are single phase, and a nanorod shaped morphology is observed for (Li, Ce)-codoping.

TiO2 film/Cu2O microgrid heterojunction with photocatalytic activity under solar light irradiation.

Coupling a narrow-band-gap semiconductor with TiO(2) is an effective method to produce photocatalysts that work under UV-vis light irradiation. Usually photocatalytic coupled-semiconductors exist mainly as powders, and photocatalytic activity is only favored when a small loading amount of narrow-band-gap semiconductor is used. Here we propose a heavy-loading photocatalyst configuration in which 51% of the surface of the TiO(2) film is covered by a Cu(2)O microgrid.

[Long-term subculture and biological characterization of the murine bone marrow endothelial cell line].

The murine bone marrow endothelial cell line (mBMEC) has been maintained by means of subculture and cryopreservation for over 10 years since it was established in our laboratory. This study was aimed to newly identify biological characteristics of this cell line for further study. The cultured mBMEC cells were observed by inverted microscopy and transmission electron microscopy (TEM).