Publications by authors named "Haile Berihulay"
With climate change bound to affect food and feed production, emphasis will shift to resilient and adapted indigenous livestock to sustain animal production. However, indigenous livestock comprise several varieties, strains and ecotypes whose genomes are poorly characterized. Here, we investigated genomic variation in an African thin-tailed Desert Sheep sampled in Sudan, using 600K genotype data generated from 92 individuals representing five ecotypes.
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- Researchers studied the autozygosity of five local Chinese sheep breeds by analyzing high-density SNP Chip data to identify runs of homozygosity (ROH), revealing how inbreeding has shaped their genomes.
- Out of 96 sheep samples, they identified 3046 ROHs, mostly in segments longer than 1-5 Mb, with an overall average genome coverage of about 12%.
- The study also found specific genomic regions associated with traits such as disease resistance and growth, suggesting the need for tailored breeding and conservation strategies for these indigenous breeds.
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- * A genome-wide association study identified two significant SNPs in the MC1R gene linked to coat colour in 75 Chinese Tan sheep, with one SNP causing an amino acid change associated with white coat colour.
- * Genotype analysis showed white sheep were homozygous (GG) while black-head sheep were mostly heterozygous (GA), suggesting that the identified mutation impacts coat colour variation in these sheep breeds.
Sheep () is one of the most economically, culturally, and socially important domestic animals. They are reared primarily for meat, milk, wool, and fur production. Sheep were reared using natural selection for a long period of time to offer these traits.
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- * Whole-genome resequencing of 44 Ethiopian goat breeds revealed millions of genetic variations, helping to identify significant traits through population differentiation and heterozygosity analyses.
- * The study uncovered key genes associated with reproductive health, body weight, and disease resistance, providing essential genetic information for future conservation and breeding strategies.
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- - The study analyzes six Chinese goat populations to understand how selection affects genomic diversity, focusing on characteristics like runs of homozygosity (ROHs) and genetic differentiation, using SNP 50K Illumina beads.
- - Results indicate that longer ROH lengths and higher inbreeding levels correlate with intense selection pressures, particularly in Guangfeng goats, while revealing relationships between certain genes and reproduction.
- - The investigation identifies multiple candidate genes linked to goat fecundity, with significant selection signatures showing differentiation between high and low reproduction groups, thus enhancing breeding strategies for genetic resource conservation.
Genome-wide linkage disequilibrium is a useful parameter to study quantitative trait locus (QTL) mapping and genetic selection. In many genomic methodologies, effective population size is an important genetic parameter because of its relationship to the loss of genetic variation, increases in inbreeding, the accumulation of mutations, and the effectiveness of selection. In this study, a total of 193 individuals were genotyped to assess the extent of LD and Ne in six Chinese goat populations using the SNP 50K BeadChip.
View Article and Find Full Text PDFAdaptation Mechanisms of Small Ruminants to Environmental Heat Stress.
Animals (Basel)
February 2019
Small ruminants are the critical source of livelihood for rural people to the development of sustainable and environmentally sound production systems. They provided a source of meat, milk, skin, and fiber. The several contributions of small ruminants to the economy of millions of rural people are however being challenged by extreme heat stress difficulties.
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