Echinatin mitigates H2O2-induced oxidative damage and apoptosis in lens epithelial cells via the Nrf2/HO-1 pathway.

Background: Oxidative stress has been reported to be an early factor in the development of cataracts. Echinatin (Ech) is an active ingredient of licorice that exhibits antioxidant effects.

Objectives: To investigate the effects of Ech on oxidative stress-induced lens epithelial cell (LEC) damage.