Enhancing Methylene Blue Adsorption Performance of TiCT@Sodium Alginate Foam Through Pore Structure Regulation.

Pore structural regulation is expected to be a facile way to enhance the adsorption performance of MXene. In this work, spherical foam composites consisting of TiCT and sodium alginate (SA) were synthesized via a vacuum freeze-drying technique. By varying the solution volume of TiCT, four distinct TiCT@SA spherical foams with honeycomb-like and lamellar structures with a pore diameter in the range of 100-300 μm were fabricated.

Navigating precision: the crucial role of next-generation sequencing recurrence risk assessment in tailoring adjuvant therapy for hormone receptor-positive, human epidermal growth factor Receptor2-negative early breast cancer.

Hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) breast cancer is the most common subtype, representing over two-thirds of new diagnoses. Adjuvant therapy, which encompasses various medications and treatment durations, is the standard approach for managing early stage HR+ HER2- breast cancer. Optimizing treatment is essential to minimize unnecessary side effects while addressing the biological variability inherent in HR+/HER2- breast cancers.

Research Status and Challenges of Mechanism, Characterization, Performance Evaluation, and Type of Nano-Pour Point Depressants in Waxy Crude Oil.

Nano-Pour point depressants have great potential to improve the low-temperature fluidity of waxy crude oil. This Review reviews the recent research progress of nano-pour point depressants in the field of crude oil pour point reduction. The effect and mechanism of nanocomposite pour point depressants are analyzed; the preparation, modification, and microstructure characterization of nanocomposite pour point depressants are introduced; the three main types of nano-pour point depressants, namely, silicon-based, carbon-based, and magnetic metal-based, are introduced; the results of the current research are outlined; and the challenges of the current research and possible directions of future research are also pointed out.

FLOT1, stabilized by WTAP/IGF2BP2 mediated N6-methyladenosine modification, predicts poor prognosis and promotes growth and invasion in gliomas.

The expression, function, and mechanism of FLOT1 (flotillin-1) remains unknown in gliomas. Here, the expression and clinical value of FLOT1 in gliomas was bioinformatically and experimentally analyzed via online omics data and local tissues. Moreover, the effects of FLOT1 depletion on cell proliferation and invasion were also detected.

F-Box Protein 43, Stabilized by N6-Methyladenosine Methylation, Enhances Hepatocellular Carcinoma Cell Growth and Invasion via Promoting p53 Degradation in a Ubiquitin Conjugating Enzyme E2 C-Dependent Manner.

The roles of F-box protein 43 (FBXO43) in carcinogenesis have been rarely revealed. The present study investigates the expression, function, and underlying mechanism of FBXO43 in hepatocellular carcinoma (HCC). Firstly, the expression and clinical significance of FBXO43 in HCC were investigated bioinformatically and experimentally using online omics data and local tissue samples.

Modeling of the Phase Inversion Point of Crude Oil Emulsion by Characterization of Crude Oil Physical Properties.

Accurate prediction of the phase inversion point (PIP) of crude oil emulsion (COE) will give important guiding significance to the mixed transportation technology during the crude oil mining process. The influence of water cut of a system on viscosity characteristics of the COE was studied by emulsification experiments with 16 kinds of crude oils having significant differences in physical properties. The results showed that under the condition of low water cut of a system, the crude oils can emulsify all the water to form stable W/O emulsions with apparent viscosities much higher than those of pure crude oils.

Ultra-fast and ultra-efficient removal of Cr (VI) by the aqueous solutions of monolayer MXene (TiCT).

Chromium (VI) removal is crucial to the safety of water resources, but there is still a lack of effective and fast dislodge methods, especially the on-site rapid remediation and emergency removal technology. Herein, the monolayer (ML) TiCT nanosheets (NSs) were prepared to remove Cr (VI) from water. The solution sample of the two-dimensional (2D) TiCT NSs demonstrate ultrafast adsorption kinetics (the concentration decreasing from 300 to 3 mg L in 10 min) and impressively high capacity (1483 mg g), which is several times higher than that of the most reported Cr (VI) adsorption by TiCT.

Prediction Model between Emulsified Water Fractions and Physicochemical Properties of Crude Oil Based on the Exergy Loss Rate.

The quantitative calculation of emulsified water fractions of crude oil-water systems is of great significance for the study of flow characteristics of multiphase flow pipelines. For a crude oil-water system with a high water fraction, the emulsified water fraction under different influencing factors was determined by emulsification experiments. It was found that the emulsified water fraction under different shearing conditions correlated well with the exergy loss rate and could be described by a power-law equation, in which two undetermined parameters relate to the crude oil physicochemical properties.

A New Method of Haemorrhagic Stroke Detection Deep Magnetic Induction Tomography.

Hemorrhage imaging is one of the most common applications of magnetic induction tomography (MIT). Depth and the mass of stroke stimulated (MSS) are the most important issues that need to be solved for this application. Transcranial magnetic stimulation (TMS) is a technique belonging to the deep brain stimulation (DBS) field, which aims at overcoming human diseases such as depression.

Novel lncRNA XLOC_032768 alleviates cisplatin-induced apoptosis and inflammatory response of renal tubular epithelial cells through TNF-α.

The cellular and molecular mechanisms through which cisplatin induces nephrotoxicity have been investigated extensively. However, the role of long non-coding RNAs (lncRNAs) in cisplatin-induced nephrotoxicity is not well known. We explored the functions and underlying mechanisms of a novel lncRNA XLOC_032768 in cisplatin-induced nephrotoxicity.

[Diagnostic value of different detection methods for Mycobacterium tuberculosis in bronchoalveolar lavage fluid from pulmonary tuberculosis patients].

To investigate the diagnostic value of different detection methods for Mycobacterium tuberculosis in bronchoalveolar lavage fluid (BALF) from patients with pulmonary tuberculosis.
 Methods: BALF from100 patients in Changsha Central Hospital from January 2013 to December 2015 was collected. Among 100 patients, 65 cases were clinically diagnosed as tuberculosis, and 35 cases served as control.

[Rapid screen of 15 basic artificial dyes in fishery products by ultra performance liquid chromatography coupled with quadrupole-time of flight mass spectrometry].

A new method was established for the simultaneous determination of 15 basic artificial dyes in fishery products by ultra performance liquid chromatography coupled with quadrupole-time of flight mass spectrometry (UPLC-Q-TOF MS). The analytes in fishery products were extracted with acetonitrile containing 10% (v/v) acetic acid, then purified by dispersive solid phase extraction with C18-silicone adsorbent. The compounds were separated by a C18 column with acetonitrile and 0.

Hydrogen sensing characteristics from carbon nanotube field emissions.

An innovative hydrogen sensing concept is demonstrated based on the field emission from multi-walled carbon nanotubes, where the low emission currents rise in proportion to hydrogen partial pressures above 10(-9) Torr. Experimental and first principles studies reveal that the sensing mechanism is attributed to the effective work function reduction from dissociative hydrogen chemisorption. The embedded Ni catalyst would assist both the hydrogen dissociation and work function reduction.

Initial Subsurface Incorporation of Oxygen into Ru(0001): A Density Functional Theory Study.

The adsorption and diffusion of oxygen on Ru(0001) surfaces as a function of coverage are systematically investigated by using density functional theory. A high incorporation barrier of low-coverage adsorbed oxygen into the subsurface is discovered. Calculations show that the adsorption of additional on-surface oxygen can lower the penetration barrier dramatically.

Relationship between the expression of MDR1 in hepatocellular cancer and its biological behaviors.

Objective: By the detection of HBV infection, AFP and AST, the targets of biological behavior and the gene expression of multi-drug resistance gene 1 (MDR1) in hepatocellular carcinoma (HCC), we investigate characteristics of the expression of MDR1 in HCC and its relationship with HCC biological behavior.

Methods: Using real-time fluorescence quantitative PCR (FQ-PCR) to detect the expressions of MDR1 in 102 samples of HCC tissue and 20 samples of non-cancerous tissue, we analyze the relationship between expressions of MDR1 and biological characteristics of HCC.

Results: The expression of MDR1 in HCC is 0.

Promoter hypermethylation of p14 (ARF) , RB, and INK4 gene family in hepatocellular carcinoma with hepatitis B virus infection.

Both hepatitis B virus (HBV) and gene methylation play important roles in hepatocarcinogenesis. However, their association between HBV infection and gene methylation is not fully understood. Cell cycle control involving RB1 gene-related cell inhibitors is one of the main regulatory pathways were reported to be altered in hepatocellular carcinoma (HCC).

A multi-channel magnetic induction tomography measurement system for human brain model imaging.

This paper proposes a multi-channel magnetic induction tomography measurement system for biological conductivity imaging in a human brain model. A hemispherical glass bowl filled with a salt solution is used as the human brain model; meanwhile, agar blocks of different conductivity are placed in the solution to simulate the intracerebral hemorrhage. The excitation and detection coils are fixed co-axially, and the axial gradiometer is used as the detection coil in order to cancel the primary field.