MicroRNA-192-5p downregulates Fat Mass and Obesity-associated Protein to aggravate renal ischemia/reperfusion injury.

Acute kidney injury (AKI) is a common disorder without effective therapy yet. Renal ischemia/reperfusion (I/R) injury is a common cause of AKI. MicroRNA miR-192-5p has been previously reported to be upregulated in AKI models.

Transverse-Sigmoid Sinus Dural Arteriovenous Fistula Concurrent With Bilateral Venous Sinus Occlusion.

Background And Significance: Dural arteriovenous fistula (DAVF) is a relatively rare type of cerebrovascular malformation with unknown pathogenesis. Here, the authors report a patient with DAVF in the left transverse-sigmoid sinus (Cognard type III) combined with occlusions of the left sigmoid sinus and right transverse sinus. The authors describe and discuss their successful treatment approach, with the aim to improve the management of this rare disorder.

ROSes-FINDER: a multi-task deep learning framework for accurate prediction of microorganism reactive oxygen species scavenging enzymes.

Reactive oxygen species (ROS) are highly reactive molecules that play important roles in microbial biological processes. However, excessive accumulation of ROS can lead to oxidative stress and cellular damage. Microorganism have evolved a diverse suite of enzymes to mitigate the harmful effects of ROS.