LncRNA GASL1 is downregulated in chronic heart failure and regulates cardiomyocyte apoptosis.

Background: TGF-β1 contributes to chronic heart failure. It is known that lncRNA GASL1 can inactivate TGF-β1 in cancer biology.

Methods: All the participants were enrolled in the First People's Hospital of Zhaoqing during the period June 2012 to June 2013.

Bufadienolides induce p53-mediated apoptosis in esophageal squamous cell carcinoma cells and .

Bufadienolides are a type of cardiotonic steroids isolated from the skin and parotid venom glands of the toad Cantor, and exhibit wide-spectrum anticancer activities. However, the effects and mechanisms of bufadienolides on esophageal squamous cell carcinoma (ESCC) cells remain unknown. In the present study, the anticancer activities of two bufadienolides, bufotalin and bufalin, were examined and .