Antioxidant and renal protective effects of Nano-selenium on adenine-induced acute renal failure in canines.

Acute renal failure is a common clinical disease in canines, affecting antioxidant levels and decreasing the body's resistance. This study aims to explore the therapeutic mechanism of Nano-selenium in acute renal failure. The histopathological and imaging changes of kidney tissue were observed with the gene and protein expression levels of Keap1, Nrf2, HO-1, and NQO1 in the kidney.

Hexavalent Chromium Causes Apoptosis and Autophagy by Inducing Mitochondrial Dysfunction and Oxidative Stress in Broiler Cardiomyocytes.

Hexavalent chromium (Cr(VI)) is a common environmental pollutant, which has a strong toxic effect on humans and animals. However, the cardiac toxicity of Cr(VI) in broilers remains to be explored. The development of heart disease is often linked to mitochondrial dysfunction especially exposure to toxic substances.