Publications by authors named "Haigang Hu"

To explore the association between serum high-sensitivity C-reactive protein (HSCRP) levels and osteoarthritis (OA) in adults, providing new evidence for the diagnosis of adult OA. We selected data from the 2015-2018 National Health and Nutrition Examination Survey (NHANES) and conducted a cross-sectional study. Serum HSCRP levels were extracted from laboratory data, and OA patients were identified through questionnaire responses.

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The aim of this study was to evaluate the biomechanical and osseointegrative properties of 3D printed porous PEEK materials loaded with strontium (Sr) and alendronate (ALN), which prepared porous cylindrical material by a fused deposition molding process, coated with Sr and ALN by hydrothermal reaction and dopamine assistance. According to the different coating materials, it could be divided into the PEEK group, PEEK-ALN group, PEEK-Sr group and PEEK-ALN-Sr group. After completing the mechanical analyses, the materials were implanted into the femoral condyles of New Zealand rabbits and the osteogenic capacity of the bracket materials was assessed by Micro-CT scanning, histology and fluorescence staining.

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Article Synopsis
  • The study aimed to compare the effectiveness of a new minimally invasive spinal surgery technique (UBE) with traditional open surgery for treating lumbar burst fractures.
  • It included 61 patients divided into two groups: one treated with the UBE method and the other with a traditional surgery approach, and both groups showed similar baseline characteristics.
  • Results indicated successful surgeries with no major complications for either method, but the study focuses on comparing surgical outcomes like operation time and recovery, which will be detailed in further follow-ups.
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Objective: To investigate the clinical significance of using 3D printing guides in modified unilateral puncture percutaneous vertebroplasty (PVP) for the treatment of osteoporotic vertebral compression fractures (OVCF), and to explore a new method for preventing paravertebral vein leakage during PVP in conjunction with a previous study of the optimal puncture-side bone cement/vertebral volume ratio(PSBCV/VV%).

Methods: This retrospective study analyzed 99 patients who underwent unilateral puncture PVP between January 2023 and December 2023. Patients were divided into a guide plate group (46 patients) and a conventional group (53 patients).

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Objective: To evaluate the effectiveness of spinal canal decompression assisted by unilateral biportal endoscopy (UBE) and percutaneous uniplanar pedicle screw internal fixation in the treatment of lumbar burst fractures with neurological symptoms.

Methods: Between June 2021 and December 2022, 10 patients with single level lumbar burst fracture with neurological symptoms were treated with spinal canal decompression assisted by UBE and percutaneous uniplanar pedicle screw internal fixation. There were 7 males and 3 females with an average age of 43.

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Objective: To investigate the factors associated with the occurrence of Baastrup's disease (BA) in patients with lumbar degenerative diseases (LDDs).

Methods: A retrospective analysis was conducted on 168 patients with LDDs (including lumbar disc herniation, lumbar spinal stenosis, and lumbar spondylolisthesis) who were treated at our hospital from January 2020 to January 2023, comprising 95 males and 73 females, aged 48-84 years.Patients were divided into two groups based on the presence of Baastrup's disease: those with BA (Group A) and those without BA (Group B).

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Objective: Lumbar spine and pelvic fractures(LPF) are combined with peripheral ligament injuries(PLI), frequently. It has been reported that the site of fracture injury is usually paralleled by the secretion of inflammatory proteins. This study aimed to investigate the causal relationship between 91 circulating inflammatory proteins and LPF and PLI by using a Two-sample Mendelian randomization (MR) analysis.

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Objective: To predict and analyse the unfavourable outcomes of early applicated percutaneous endoscopic interlaminar discectomy for lumbar disc herniation.

Methods: Information of 426 patients treated by early applicated percutaneous endoscopic interlaminar discectomy (PEID) for lumbar disc herniation (LDH) at our hospital from June 2017 to October 2021 in addition to 17 other features was collected. The risk factors were selected by the least absolute shrinkage and selection operator method (LASSO) regression.

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Article Synopsis
  • This study proposes a new classification system for lumbar Basstrup's disease, categorizing patients based on radiographic findings and clinical symptoms, with two main types and several subtypes.
  • Researchers conducted a retrospective analysis of 116 patients from January 2019 to January 2022, using various imaging methods and reassessing the classification for reliability among five physicians.
  • The results showed that 51.72% of patients had a single segment of disease, while 48.28% had multiple segments, with 59.48% experiencing clinical symptoms like low back pain and nerve issues.
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Objective: Accurately inserting pedicle screws is the key point of posterior pedicle screw fixation for lower cervical spine (C3-C7) instability. 3D printing technology can improve the accuracy of screw placement. This study compared the safety of 3D-printed flexible drill guiding template vs.

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Objectives: To verify the clinical significance of the best puncture-side bone cement/vertebral volume ratio (PSBCV/VV%) and bone cement leakage in paravertebral veins during vertebroplasty.

Methods: This was a retrospective analysis of a total of 210 patients from September 2021 to December 2022, who were divided into an observation group (110 patients) and a control group (100 patients). In the observation group, patients' preoperative computed tomography (CT) data were imported into Mimics software, and the VV was calculated using the three-dimensional (3D) reconstruction function.

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Objective: To investigate the clinical effect of unilateral puncture vertebroplasty with curved diffusion needle (CDN) in the treatment of thoracolumbar osteoporotic vertebral compression fracture (OVCFs).

Methods: We used the method of a retrospective study. The clinical data of 38 patients with OVCFs treated by unilateral puncture vertebroplasty with curved diffusion needle from January 2021 to January 2022 were analyzed.

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Objective: Posterior pelvic ring sacroiliac screws are preferred by clinicians for their good biomechanical performance. However, there are few studies on mechanical analysis and intraoperative screw insertion of the dysplastic sacrum and sacroiliac screw. This study investigated the biomechanical performance of oblique sacroiliac screws (OSS) in S1 combined with transiliac-transsacral screws (TTSs) in S2 for pelvic fracture or sacroiliac dislocation with dysplastic sacrum and evaluated the safety of screw placement assisted by the navigation template.

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The objective of this study as to evaluate the biomechanical and osteointegration properties of 3D printed porous polyetheretherketone (PEEK) with hydroxyapatite (HA) coating by simulated body fluid (SBF) method. Cylindrical scaffolds were designed and fabricated by using PEEK material through fused deposition molding (FDM). The scaffolds were divided into solid group, porous group and porous-HA group (decorated by hydroxyapatite).

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Objective: To evaluate the efficacy and feasibility of percutaneous endoscopic interlaminar discectomy (PEID) via the inner border of the inferior pedicle approach for downmigrated disc herniation.

Methods: Seventeen patients who had downmigrated disc herniation were included in this study from May 2020 to February 2021. After PEID via the inner border of the inferior pedicle approach, a retrospective study was conducted on all patients.

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Objective: To investigate the influence of axis pedicle and intra-axial vertebral artery (IAVA) alignment on C pedicle screw placement by measuring the data of head and neck CT angiography.

Methods: The axis pedicle diameter (D), isthmus height (H), isthmus thickness (T), and IAVA alignment types were measured in 116 patients (232 sides) who underwent head and neck CT angiography examinations between January 2020 and June 2020. Defined the IAVA offset direction by referencing the vertical line through the center of C transverse foramen on the coronal scan, it was divided into lateral (L), neutral (N), and medial (M).

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Objectives: To explore the influencing factors of bone cement leakage in the paravertebral vein after vertebroplasty for the treatment of osteoporotic vertebral compression fractures (OVCFs) and to determine the correlation between the puncture-side bone cement/vertebral body volume ratio and bone cement leakage in the paravertebral vein.

Methods: This was a retrospective analysis of 495 patients (585 vertebral bodies) with OVCFs treated from August 2018 to May 2021 in our hospital. The patients' postoperative CT data were imported into Mimics software, and the three-dimensional(3D) reconstruction function was used to calculate the bone cement volume (BCV), puncture-side bone cement volume (PSBCV), and vertebral body volume (VBV); the bone cement/vertebral body volume ratio (BCV/VCV%) and puncture-side bone cement/vertebral body volume ratio (PSBCV/VCV%) were additionally calculated.

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Objective: To evaluate the effectiveness of Curved Diffusion Needle in unilateral percutaneous vertebroplasty (PVP) by compared with bilateral PVP.

Methods: A clinical data of 93 patients with osteoporotic vertebral compression fracture (OVCF) treated with PVP between January 2020 and January 2021 was retrospectively analyzed, including 47 patients underwent unilateral PVP assisted with Curved Diffusion Needle (unilateral group) and 46 patients underwent bilateral PVP (bilateral group). There was no significant difference in gender, age, cause of injury, time from injury to operation, T value of bone mineral density, AO classification, distribution of injured vertebrae, and preoperative visual analogue scale (VAS) score, Oswestry disability index (ODI), relative height of injured vertebrae, and Cobb angle between the two groups ( >0.

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Objective: To develop and validate the efficacy of a 3D-printed screw-rod auxiliary system for unstable atlas fractures.

Methods: This research is a retrospective analysis, and a total of 14 patients, including 11 males and three females, were enrolled in our hospital from January 2017 to March 2019 who underwent occipitocervical fusion assisted by the 3D-printed screw-rod auxiliary system were reviewed, and with an average age of 53.21 ± 14.

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Study Design: An anatomic analysis.

Objective: To investigate the feasibility of the ideal atlas pedicle screw trajectory perpendicular to the coronal plane via atlas digital 3D reconstruction.

Methods: One hundred adult atlases were evaluated in this study.

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Objective: To evaluate the effectiveness of three-dimensional (3D) printing assisted internal fixation for unstable pelvic fractures.

Methods: The clinical data of 28 patients with unstable pelvic fractures admitted between March 2015 and December 2017 were retrospectively analyzed. The patients were divided into two groups according to different surgical methods.

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Objective: To explore the surgical treatment strategy of the vertebral "shell" after thoracolumbar fracture, and provide clinical reference for the intervention and treatment of "shell".

Methods: Between June 2015 and January 2017, 53 patients with high risk of vertebral "shell" after thoracolumbar fracture surgery were enrolled in a prospective study according to the selection criteria. All patients were randomly divided into two groups according to the order of treatment, 27 cases in the treatment group were treated with short-segment fixation combined with vertebral reconstruction, 26 cases in the control group were treated with short-segment fixation.

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Objective: To analyze the imaging characteristics of vertebral "shell" phenomenon of thoracolumbar fractures after posterior reduction and to explore the relationship between vertebral "shell" and fracture healing.

Methods: Between January 2013 and December 2015, the clinical data of 116 patients with thoracolumbar fractures treated with posterior pedicle screw-rod system reduction and internal fixation were analyzed retrospectively. There were 72 males and 44 females, aged 22-66 years (mean, 43 years).

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Objective: To evaluate the safety of photoelectric guided navigation unilateral puncture of the percutaneous kyphoplasty (PKP) in the treatment of thoracolumbar osteoporotic vertebral compression fracture (OVCF).

Methods: A randomized controlled clinical research was performed between June 2015 and January 2017. Eighty-five cases of OVCF were treated with photoelectric guided navigation unilateral puncture of the PKP (trial group, 43 cases) or C arm fluoroscopy unilateral puncture of the PKP (control group, 42 cases) respectively.

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Objective: To compare the effectiveness of minimally invasive percutaneous internal fixation and traditional open reduction via Henry approach and internal fixation in the treatment of unstable distal radial fractures.

Methods: Fifty-six patients with unstable distal radial fractures that met the selection criteria between October 2013 and December 2014 were randomly divided into minimally invasive group (26 cases) and traditional group (30 cases). They were treated with oblique T-shaped locking plate internal fixation via minimally invasive percutaneous approach or traditional Henry approach.

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