Publications by authors named "Haifeng Mi"

Article Synopsis
  • The study focused on how two isoforms of ribosomal protein S6 kinase 1 (S6K1α and S6K1β) affect the expression of genes related to glycolysis and gluconeogenesis in juvenile blunt snout bream.
  • Researchers cloned and characterized these isoforms, revealing their sequences and significant expression in heart and gonads.
  • The use of siRNAs demonstrated that S6K1α primarily regulates gluconeogenesis, while both S6K1α and S6K1β work together to co-regulate glycolysis, highlighting their distinct roles in metabolic processes.
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A 9-week feeding trial was conducted to evaluate the effects of replacing soybean meal (SBM) with sunflower meal (SM) or fermented sunflower meal (FSM) on the growth performance, intestinal microbiota, and intestinal health of genetically improved farmed tilapia () (initial weight 6.55 ± 0.01 g).

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Zearalenone (ZEA) is a widely distributed mycotoxin that presents a substantial worldwide health risk to animals. Several natural compounds have shown promise in mitigating the detrimental impacts of ZEA. This study examined the detoxification potential of previously identified compounds by utilizing zebrafish embryos as a model organism.

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An 8-week feeding trial was conducted to assess the impact of replacing fish meal (FM) with rubber seed cake (RSC) on growth performance, digestive enzyme activity of the gut, antioxidant capacity and protein metabolism-related parameters of plasma and liver in juvenile Asian red-tailed catfish () with an average body weight of 3.21 g. Four isonitrogenous (41.

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  • An eight-week study explored how dietary ferroporphyrin (FPR) impacts gibel carp in terms of growth, immunity, and health.
  • Findings showed that 0.01% FPR improved overall fish nourishment by increasing proteins and cholesterol, while higher levels (0.03% and 0.04%) raised certain enzymes but decreased glucose and triglycerides.
  • Immunity improved with 0.01% and 0.02% FPR, but higher levels negatively affected antioxidant and oxygen-carrying abilities, indicating a careful balance is needed in dietary supplementation.
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  • The experiment tested the effects of chlorogenic acid (CGA) on largemouth bass over eight weeks, with supplementation levels at 0, 60, 120, 180, and 240 mg/kg.
  • The groups receiving 180 and 240 mg/kg of CGA showed significant improvements in growth metrics and a reduction in feed conversion ratio (FCR) compared to the control group.
  • CGA supplementation enhanced antioxidant levels and reduced inflammation in the fish, suggesting it could be an effective dietary supplement for promoting the health and growth of largemouth bass.
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This study investigated the role of cholecystokinin () in the feeding regulation of largemouth bass () via peptide activation and antagonist inhibition. The results show that the gene was expressed in various tissues, with the highest expression level occurring in the brain. Feeding, continuous feeding, and refeeding after fasting could significantly improve the mRNA levels of in the brain.

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  • Selenium (Se) is an important trace element that supports cellular functions like redox balance and immune responses, particularly in fish like grass carp.
  • A study on grass carp showed that feeding them with an optimal level of Se (0.40 mg/kg diet) can reduce intestinal damage from Aeromonas hydrophila, boost immune responses, and regulate pro-inflammatory and anti-inflammatory factors.
  • The findings suggest that appropriate Se levels help alleviate intestinal inflammation by inhibiting endoplasmic reticulum stress and autophagy, with specific Se requirements identified at 0.59 mg/kg for acid phosphatase and 0.51 mg/kg for lysozyme in juvenile grass carp.
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  • This study evaluated how different replacements of fish meal (FM) with soy protein concentrate (SPC) impact juvenile largemouth bass in terms of growth, metabolism, and health over a 56-day period.
  • The groups with 0%, 25%, and 50% SPC showed better growth rates and feed conversion ratios compared to the 75% and 100% SPC groups, indicating that high levels of SPC may negatively affect growth performance.
  • Additionally, changes in antioxidant enzyme activities and inflammatory response were noted, with lower activities seen in groups with more SPC, suggesting that replacing FM with SPC can affect the fish’s health and metabolic responses.
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To reveal the effects of waterborne copper stress on gene expression changes, molecular pathways, and physiological functions in , juvenile fish were equally divided into two experimental groups, and the copper levels were 1.61 ± 0.03 mg/L (copper-exposed group) and 0 mg/L (control group), respectively.

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  • Ochratoxin A (OTA) is a harmful pollutant that affects aquafeeds, and this study focuses on curcumin (Cur) as a potential solution to mitigate its toxic effects on muscle cells (myoblasts).
  • The research involved 720 grass carp divided into four groups to test the effects of OTA and Cur over 60 days, revealing that Cur improved cell growth and protein development while countering the negative impacts of OTA.
  • The findings suggest that Cur not only enhances muscle development by activating certain signaling pathways and proteins but also inhibits gene expression related to protein degradation, highlighting its potential for alleviating OTA myotoxicity.
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Hypoxia in water environment is one of the important problems faced by intensive aquaculture. Under hypoxia stress, the effects of dietary thiamine were investigated on grass carp gill tissue damage and their mechanisms. Six thiamine diets with different thiamine levels (0.

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A nine-week feeding trial was conducted to evaluate the effects of replacing wheat bran (WB) with palm kernel cake (PKC) or fermented palm kernel cake (FPKC) on the growth performance, intestinal microbiota and intestinal health of genetically improved farmed tilapia (GIFT, ) (initial weight 7.00 ± 0.01 g).

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A 12-week feeding trial was conducted to evaluate the effects of replacing soybean meal with different types of rapeseed meal (RSM; Chinese 95-type (oil press model) rapeseed meal [C95RM], Chinese 200-type rapeseed meal [C200RM], cold pressed rapeseed cake [CPRC], Indian rapeseed meal [IRM] and Canadian rapeseed meal [CRM]) on growth, antioxidant capacity, non-specific immunity and infection tolerance in 990 fingering (average weight 12.77 ± 0.01 g) rainbow trout ().

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Vitamin E (VE) is an essential lipid-soluble vitamin that improves the fish flesh quality. However, the underlying molecular mechanisms remain unclear. This study aimed to investigate the effects of VE on growth performance and flesh quality in sub-adult grass carp ().

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Bacterial pathogens destroy the structural integrity of functional organs in fish, leading to severe challenges in the aquaculture industry. Vitamin D (VD) prevents bacterial infections and strengthens immune system function via vitamin D receptor (VDR). However, the correlation between VD/VDR and the structural integrity of functional organs remains unclarified.

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This experiment was conducted to investigate the impacts of dietary selenium yeast (SeY) on the growth performance, fish body composition, metabolic ability, antioxidant capability, immunity and inflammatory responses in juvenile black carp (Mylopharyngodn piceus). The base diet was supplemented with 0.00, 0.

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Background: Citrus pulp (CP) is rich in pectin, and studies have shown that pectin possesses antioxidant, anti-inflammatory, and gut microbiota-regulating properties. However, the application of CP in aquafeed is limited. In this study, the effect of dietary inclusion of CP on the intestinal health of largemouth bass (Micropterus salmoides) was investigated.

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Background: Muscle represents a unique and complex system with many components and comprises the major edible part of animals. Vitamin D is a critical nutrient for animals and is known to enhance calcium absorption and immune response. In recent years, dietary vitamin D supplementation in livestock has received increased attention due to biological responses including improving shear force in mammalian meat.

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Flavobacterium columnare (F. columnare) is one of the deadliest fish pathogens causing bacterial gill rot disease in various freshwater fish species globally. Tea polyphenols (TPs) are an inexpensive product extracted from tea that have received much attention as a feed additive in aquaculture.

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Arabinoxylan (AX) has been deemed as an antinutritional factor, but limited information has addressed the effects of dietary AX on intestinal health of fish. The present study investigated the effects of dietary AX on intestinal mucosal physical and immunological barriers of rainbow trout (Oncorhynchus mykiss). Five isoproteic and isolipidic experimental diets (AXE, AX0, AX2.

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The function of algae extract (AE) in fishmeal (FM) substitution with plant proteins in the diets of Gibel carp () was investigated during a 56-day trial. Diets 1 and 2 contained 10% FM, Diets 3 and 4 contained 5% FM, and Diet 5 and 6 contained 0% FM. In contrast, Diets 2, 4, and 6 were supplemented with 0.

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The n6/n3 ratios improved meat quality of terrestrial animals, but alpha-linolenic acid/linoleic acid (ALA/LNA) ratios were rarely studied in aquatic animals. In this study, sub-adult grass carp were fed diets fed diets containing six varying ALA/LNA ratios (0.03, 0.

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Ochratoxin A (OTA), a notorious pollutant widely present worldwide, seriously pollutes aquafeeds. This paper aims to explore the toxicity effects of OTA by the way of diet on the skin barrier in grass carp (Ctenopharyngodon idella). Results were shown as follows in the skin: (1) OTA increased the mRNA abundances of uptake transporter proteins (e.

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Aquafeeds are susceptible to contamination caused by aflatoxin B1 (AFB1). The gill of fish is an important respiratory organ. However, few studies have investigated the effects of dietary AFB1 exposure on gill.

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