Synthesis of designed new 1,3,4-oxadiazole functionalized pyrano [2,3-f] chromene derivatives and their antimicrobial activities.

Diethyl 2-(((4-methyl-2-oxo-2H-chromen-7-yl)oxy)methylene)malonate was synthesized from coumarin 1 and diethyl ethoxymethylene malonate in ethanol, followed by cyclization in diphenyl ether to give chromene-9-carboxylate . Sugar hydrazones were formed by reacting hydrazide with D-galactose, D-mannose, and D-xylose, then acetylated to per--acetyl derivatives . Heating with acetic anhydride at 100 °C gave oxadiazolines .

Review: Factors influencing parents' decisions to vaccinate children against COVID-19.

Introduction: Vaccination is a cornerstone of public health, significantly safeguarding children's health. Despite the imperative of achieving extensive COVID-19 vaccine coverage, vaccine hesitancy poses a major challenge.

Objective: This review's aim is to analyze parental COVID-19 vaccine acceptance and hesitancy during the COVID-19 pandemic and elucidate the factors that influenced their decisions.

Electrospun glass nanofibers to strengthen polycarbonate plastic glass toward photoluminescent smart materials.

Electrospun glass nanofibers (GNFs) were used to strengthen polycarbonate (PC) to create long-persistent photoluminescent and fluorescent smart materials such as afterglow concrete and smart window. Physical integration of lanthanide-activated aluminate (LA) nanoparticles (NPs) yielded transparent GNFs@PC smart sheets. Spectral investigations utilizing photoluminescence and CIE Lab parameters were performed to confirm that the translucent appearance of GNFs@PC changed to green when exposed to UV light.

C-N Axial Chiral Hypervalent Iodine Reagents: Catalytic Stereoselective α-Oxytosylation of Ketones.

A simple synthesis of a library of novel C-N axially chiral iodoarenes is achieved in a three-step synthesis from commercially available aniline derivatives. C-N axial chiral iodine reagents are rarely investigated in the hypervalent iodine arena. The potential of the novel chiral iodoarenes as organocatalysts for stereoselective oxidative transformations is assessed using the well explored, but challenging stereoselective α-oxytosylation of ketones.

Parental acceptance of silver Diamine fluoride application on primary dentition: a systematic review and meta-analysis.

Background: This systematic review of the literature was carried out to assess parental acceptance for silver diamine fluoride (SDF) application and esthetic outcome on their children primary dentition and evaluate factors that might influence their acceptance.

Methods: Our research protocol included a search strategy, inclusion/exclusion criteria, and a data extraction plan. The search engines we used were PubMed, Google Scholar, and Science Direct.

Synthesis, characterisation, and reactivity of novel pseudocyclic hypervalent iodine reagents with heteroaryl carbonyl substituents.

Two new hypervalent iodine reagents containing furan and thiophene moieties in addition to a carbonyl group in the vicinity of the iodine atom were synthesised and characterised. The X-ray analysis of both compounds revealed a strong intramolecular contact between the carbonyl oxygen and the hypervalent iodine atom with tosylate as a counter ion. The two reagents showed a broad range of synthetic applications and proved to be versatile oxidizing agents.

Continuous-Flow Electrochemical Generator of Hypervalent Iodine Reagents: Synthetic Applications.

An efficient and reliable electrochemical generator of hypervalent iodine reagents has been developed. In the anodic oxidation of iodoarenes to hypervalent iodine reagents under flow conditions, the use of electricity replaces hazardous and costly chemical oxidants. Unstable hypervalent iodine reagents can be prepared easily and coupled with different substrates to achieve oxidative transformations in high yields.

Feasibility and safety of day-surgery laparoscopic cholecystectomy: a single-institution 5-year experience of 1140 cases.

Backgrounds/aims: We report our experience with day-surgery laparoscopic cholecystectomy and assess its feasibility and safety.

Methods: Data was collected on all the patients who underwent day-surgery laparoscopic cholecystectomy between February 2009 and February 2014 at Prince Sultan Military Medical City, Riyadh, Kingdom of Saudi Arabia. All patients had symptomatic cholelithiasis that was proven on imaging studies with clearance of the common bile duct.