Publications by authors named "Haider Thaer Abdulhameed"
Article Synopsis
- * These proteases, including SERA-5, DPAP-1, and Falcipains, are essential for processes like the rupture of the parasitophorous vacuole membrane during gametogenesis and merozoite invasion into red blood cells.
- * Understanding the roles of these cysteine proteases could lead to the development of innovative therapies to combat malaria and address issues of drug resistance.
This study was conducted to explore the interaction between two plant-based antiplasmodial compounds, gartanin and friedelin, and bovine serum albumin (BSA). The objectives aimed to elucidate the binding characteristics, structural changes, and thermodynamic parameters associated with the interaction. Various methods were used including UV-vis, fluorescence, and circular dichroism spectroscopy, supported by molecular docking and molecular dynamics simulation.
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