Intertwined Fano resonances in sub-wavelength metallic gratings: omnidirectional and wideband optical transmission.

Metallic gratings can be used as infrared filters, but their performance is often limited by bandwidth restrictions due to metallic losses. In this work, we propose a metallic groove-slit-groove (GSG) structure that overcomes these limitations by exhibiting a large bandwidth, angularly independent, extraordinary optical transmission. Our design achieves high transmission efficiency in the longwave infrared range, driven by Fano-type resonances created through the interaction between the grooves and the central slit.

Impact of the Biocontrol Product, Esquive WP, on the Indigenous Grapevine Wood Microbiome after a 6-Year Application Period.

Grapevine trunk diseases (GTDs) are currently limiting grapevine productivity in many vineyards worldwide. As no chemical treatments are registered to control GTDs, biocontrol agents are being tested against these diseases. Esquive WP, based on the fungus -1237 strain, is the first biocontrol product registered in France to control GTDs.

Two Paenibacillus spp. strains promote grapevine wood degradation by the fungus Fomitiporia mediterranea: from degradation experiments to genome analyses.

Ascomycetes, basidiomycetes and deuteromycetes can degrade wood, but less attention has been paid to basidiomycetes involved in Esca, a major Grapevine Trunk Disease. Using a wood sawdust microcosm system, we compared the wood degradation of three grapevine cultivars inoculated with Fomitiporia mediterranea M. Fisch, a basidiomycete responsible for white-rot development and involved in Esca disease.

Isolated lateral radial head dislocation in a child: A case report and literature review.

Introduction: Radial head dislocations in children can result from congenital anomalies, traumatic events, or as part of more complex injuries like Monteggia fractures. These dislocations are rare and may be overlooked unless considered in differential diagnoses.

Case Presentation: We describe a unique instance of a post-traumatic isolated lateral radial head dislocation in a 5-year-old boy with no previous medical concerns.

Experimental Investigation of the Thermal Emission Cross Section of Nanoresonators Using Hierarchical Poisson-Disk Distributions.

Effective cross sections of nano-objects are fundamental properties that determine their ability to interact with light. However, measuring them for individual resonators directly and quantitatively remains challenging, particularly because of the very low signals involved. Here, we experimentally measure the thermal emission cross section of metal-insulator-metal nanoresonators using a stealthy hyperuniform distribution based on a hierarchical Poisson-disk algorithm.

The nuclear entry of the aryl hydrocarbon receptor (AHR) relies on the first nuclear localization signal and can be negatively regulated through IMPα/β specific inhibitors.

The human aryl hydrocarbon receptor (AHR) undergoes continuous shuttling between nucleus and cytoplasm. Binding to exogenous or endogenous ligands promotes its rapid nuclear import. The proposed mechanism for the ligand-dependent import is based on exposing the bipartite nuclear localisation signal (NLS) to members of the importin (IMP) superfamily.

Consensus Statement on the Use of Botulinum Neurotoxin in the Middle East.

Background: Aesthetic minimally invasive procedures have become very popular and culturally acceptable among Middle Eastern populations. Botulinum neurotoxin type A (BoNTA) is a valuable treatment modality for many cosmetic as well as therapeutic indications. The presence of BoNTA in our toolkit has revolutionized the field of aesthetic medicine to the point where it is now one of the most commonly performed cosmetic procedures worldwide.

New patterns of the tree beta diversity and its determinants in the largest savanna and wetland biomes of South America.

Clear and data-driven bioregionalizations can provide a framework to test hypotheses and base biodiversity conservation. Here we used occurrence and abundance data in combination with objective analytical methods to propose two bioregionalization schemes for tree species of the Cerrado and the Pantanal in South America. We also evaluated the contribution of three sets of determinants of the occurrence- and abundance-based subregions.

Fluorinated Benzofuran and Dihydrobenzofuran as Anti-Inflammatory and Potential Anticancer Agents.

Benzofuran and 2,3-dihydrobenzofuran scaffolds are heterocycles of high value in medicinal chemistry and drug synthesis. Targeting inflammation in cancer associated with chronic inflammation is a promising therapy. In the present study, we investigated the anti-inflammatory effects of fluorinated benzofuran and dihydrobenzofuran derivatives in macrophages and in the air pouch model of inflammation, as well as their anticancer effects in the human colorectal adenocarcinoma cell line HCT116.

Microbial Biological Control of Fungi Associated with Grapevine Trunk Diseases: A Review of Strain Diversity, Modes of Action, and Advantages and Limits of Current Strategies.

Grapevine trunk diseases (GTDs) are currently among the most important health challenges for viticulture in the world. Esca, Botryosphaeria dieback, and Eutypa dieback are the most current GTDs caused by fungi in mature vineyards. Their incidence has increased over the last two decades, mainly after the ban of sodium arsenate, carbendazim, and benomyl in the early 2000s.

Deciphering Plant-Induced Responses toward and Attacks in Two Grapevine Cultivars Colonized by the Root Biocontrol Oomycete, .

Two major diseases that affect grapevine leaves and berries are controlled by the oomycete . As the efficacy of biocontrol agents strongly depends on factors such as the trophic behaviors of pathogens and cultivar susceptibility, a two-disease approach was implemented to evaluate the activity of against (the necrotrophic fungus of gray mold) and (the biotrophic oomycete of downy mildew) on two grapevine cultivars with different susceptibilities to these two pathogens. The results show that grapevine root inoculation with significantly reduced and infection on the leaves of the two cultivars, but with differences.

Verbal fluency in Lebanese children: Preliminary normative data, sociodemographic determinants, and patterns of clustering and switching.

This study assessed the quantitative and qualitative performance of Lebanese-speaking children on verbal fluency (VF) tasks and investigated the effects of sociodemographic characteristics. This study included 219 Lebanese children aged between 5 and 12 years and 11 months, whose native language is Lebanese-Arabic. Semantic and letter VF tasks were assessed using a range of categories and letters.

Investigation of the Associations between a Nanomaterial's Microrheology and Toxicology.

With the advent of Nanotechnology, the use of nanomaterials in consumer products is increasing on a daily basis, due to which a deep understanding and proper investigation regarding their safety and risk assessment should be a major priority. To date, there is no investigation regarding the microrheological properties of nanomaterials (NMs) in biological media. In our study, we utilized models to select the suitable NMs based on their physicochemical properties such as solubility and lipophilicity.

Descriptive epidemiology of soft tissue and bone sarcomas in Lebanon.

Objectives: Most epidemiologic studies on soft tissue sarcomas (STS) and bone sarcomas (BS) are performed in western countries, with few in the Middle East and North Africa region. We describe the epidemiology of sarcomas in Lebanon using the medical records database at the American University of Beirut Medical Center (AUBMC).

Methods: This single-center retrospective cohort study included patients with sarcomas registered in the database between 2015 and 2019.

Anxiety, depression and PTSD in children and adolescents following the Beirut port explosion.

Background: On August 4, 2020, Beirut's port experienced one of the strongest non-nuclear explosions in history, killing approximately 200 people, displacing 300,000 persons, and injuring more than 1000 children.

Methods: An online anonymous survey assessed the prevalence of probable mental health disorders (MHDs) and impact of blast-related and other factors controlling for sociodemographics in 801 children aged 8 to 17 years old.

Results: About two thirds (64%) were screened positive for probable anxiety using the Screen for Childhood Anxiety Related Disorder, 52% for probable PTSD using CRIES-13, and 33% for probable depression using the Mood and Feelings Questionnaire (MFQ).

Three-dimensional dispersion entropy for uterine fibroid texture quantification and post-embolization evaluation.

Background And Objective: Uterine fibroids are benign tumors that could lead to symptoms complicating a patient's daily life. Those fibroids can be treated using uterine fibroid embolization (UFE), an effective non-surgical procedure. However, objectively quantifying the benefits of such a procedure, and the patient's quality of life, is rather challenging.

Sever's Disease of the Pediatric Population: Clinical, Pathologic, and Therapeutic Considerations.

Sever's disease is an underreported prevalent pediatric condition that causes heel pain in children worldwide. It is often described as an overuse injury that can present with either unilateral or bilateral heel pain. Even though the exact mechanism of injury is unknown, it is often thought it involves repetitive stress and pressure on the calcaneal growth plate.

The role of DNA-binding and ARNT dimerization on the nucleo-cytoplasmic translocation of the aryl hydrocarbon receptor.

The human aryl hydrocarbon receptor (AHR) is predominantly located in the cytoplasm, while activation depends on its nuclear translocation. Binding to endogenous or xenobiotic ligands terminates the basal nucleo-cytoplasmic shuttling and stabilizes an exclusive nuclear population. The precise mechanisms that facilitate such stable nuclear accumulation remain to be clarified as essential step in the activation cascade.

Bacteria associated with wood tissues of Esca-diseased grapevines: functional diversity and synergy with Fomitiporia mediterranea to degrade wood components.

Fungi are considered to cause grapevine trunk diseases such as esca that result in wood degradation. For instance, the basidiomycete Fomitiporia mediterranea (Fmed) is overabundant in white rot, a key type of wood-necrosis associated with esca. However, many bacteria colonize the grapevine wood too, including the white rot.

Towards perfect metallic behavior in optical resonant nanostructures.

Looking for a perfect metallic behavior is a crucial research line for metamaterials scientists. This paper outlines a versatile strategy based on a contrast of dielectric index to control dissipative losses in metal within waveguides and resonant nanostructures. This permits us to tune the quality factor of the guided mode and of the resonance over a large range, up to eight orders of magnitude, and over a broad spectral band, from visible to millimeter waves.

Long-term follow-up of children treated with the Repiphysis expandable prosthesis for lower extremity bone sarcoma.

Expandable endoprostheses provide a limb salvage option for skeletally immature patients with bone sarcoma of the lower extremities. Initial reports of the Repiphysis prosthesis were encouraging; however, medium-term follow-up revealed high complication rates. We report on the long-term follow-up of a cohort of patients treated with the Repiphysis prosthesis.

The C-BIG Repository: an Institution-Level Open Science Platform.

In January 2016, the Montreal Neurological Institute-Hospital (The Neuro) declared itself an Open Science organization. This vision extends beyond efforts by individual scientists seeking to release individual datasets, software tools, or building platforms that provide for the free dissemination of such information. It involves multiple stakeholders and an infrastructure that considers governance, ethics, computational resourcing, physical design, workflows, training, education, and intra-institutional reporting structures.

Extraskeletal Ewing sarcoma: Diagnosis, management and prognosis.

Extraskeletal Ewing sarcoma (EES) is a relatively uncommon primary tumor of the soft tissues, which accounts for 20-30% of all reported cases of ES. Being uncommon, all members of the ES family tumors are treated following the same general protocol of sarcoma tumors. The present review summarizes the diagnosis, management and prognosis of EES, focusing on the differences between the subtypes of ESS.

Experimental demonstration of second-harmonic generation in high χ metasurfaces.

Metasurfaces able to concentrate light at various wavelengths are promising for enhancing nonlinear interactions. In this Letter, we experimentally demonstrate infrared second-harmonic generation (SHG) by a multi-resonant nanostructure. A 100 GaAs layer embedded in a metal-insulator-metal waveguide is shown to support various localized resonances.