ZC3H13 Inhibits the Progression of Hepatocellular Carcinoma through mA-PKM2-Mediated Glycolysis and Enhances Chemosensitivity.

Objective: N-Methyladenosine (mA) is the most prevalent RNA epigenetic modulation in eukaryotic cells, which serves a critical role in diverse physiological processes. Emerging evidences indicate the prognostic significance of mA regulator ZC3H13 in hepatocellular carcinoma (HCC). Herein, this study was conducted for revealing biological functions and mechanisms of ZC3H13 in HCC.