NO emission factors in bubbling fluidized bed incineration of municipal sewage sludge: The China case.

The NO emissions resulting from sludge incineration are estimated using the default values published by the Intergovernmental Panel on Climate Change (IPCC), which may differ significantly from the actual emissions. In this investigation, NO emissions from four sludge incineration lines in two plants were monitored for varying durations. The variation in NO emission factors (EFs) between incineration lines of the same plant was much smaller than the difference between different plants.

Insight into the formation of polychlorinated dibenzo-p-dioxins and dibenzofurans in hazardous waste incineration and incinerators: Formation process and reduction strategy.

Incineration technology has been widely adopted to safely dispose of hazardous waste (HW). While the incineration process causes the formation of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs). Due to its extreme toxicity, many scholars have been committed to determining the PCDD/F formation process and reducing emissions in incinerators.

An interpretable model predicts visual outcomes of no light perception eyes after open globe injury.

Background: The visual outcome of open globe injury (OGI)-no light perception (NLP) eyes is unpredictable traditionally. This study aimed to develop a model to predict the visual outcomes of vitrectomy surgery in OGI-NLP eyes using a machine learning algorithm and to provide an interpretable system for the prediction results.

Methods: Clinical data of 459 OGI-NLP eyes were retrospectively collected from 19 medical centres across China to establish a training data set for developing a model, called 'VisionGo', which can predict the visual outcome of the patients involved and compare with the Ocular Trauma Score (OTS).

Quantitative acquisition of differential absorption cross sections of chlorobenzenes at different temperatures.

Chlorobenzene is considered an essential organic synthesis intermediate and a precursor for the generation of persistent organic compounds in the waste disposal process, for which accurate detection of gaseous chlorobenzene can further help understand and control various chemical processes and effectively reduce pollution. Differential optical absorption spectroscopy is a reliable online method for detecting gaseous chlorobenzenes. It is crucial to investigate the effect of temperature on the optical absorption of the chlorobenzenes to quantify chlorobenzenes more precisely at various temperatures.

Circulating microRNA-103a-3p could be a diagnostic and prognostic biomarker for breast cancer.

Breast cancer (BC) is the most frequent cancer for women worldwide. Recently, a spectrum of cell-free circulating microRNAs (miR) has been recognized as promising biomarkers for BC diagnosis and prognosis, among which miR-103a-3p has been reported in several types of human cancer. However, the role of miR-103a-3p in BC remains unknown.

A bibliometric analysis of the application of procalcitonin in patients in the intensive care unit.

Background: Patients in the intensive care unit (ICU) often have serious infections, and anti-infection treatment is vital for these patients. Procalcitonin (PCT) is often used to identify bacterial infections and monitor the effectiveness of anti-infection treatments. This study aims to analyze the current research hotspots of the application of PCT in ICU patients, and to suggest future research directions.

The application of procalcitonin in respiratory diseases: an evaluation of the current research literature.

Background: Procalcitonin (PCT) can effectively identify bacterial infections and can be used for risk prediction and antimicrobial treatment in patients with unexplained fever and critically ill patients. In this study, statistical analyses of the literature were performed to clarify the application and research status of PCT in respiratory diseases. Future research directions are discussed.

Dexmedetomidine ameliorates lipopolysaccharide-induced acute lung injury by inhibiting the PI3K/Akt/FoxO1 signaling pathway.

Purpose: Dexmedetomidine (DEX) has been associated with inflammation, oxidative stress, and apoptosis, but its effects on lipopolysaccharide (LPS)-induced lung injury remain uncertain. The present study explored the effects of DEX on LPS-induced lung injury and studied the possible molecular mechanisms by testing the effects of the phosphoinositide-3 kinase (PI3K) inhibitor LY294002 and BEZ235.

Methods: Seventy C57BL/6 mice were randomly divided into the control, LPS, LPS + DEX, LPS + LY294002, LPS + BEZ235, LPS + DEX + LY294002, and LPS + DEX + BEZ235groups.

Effect of Notch1 on neural tube defects and neural stem cell differentiation induced by all‑trans retinoic acid.

Neural tube defects (NTDs) are the most serious and common birth defects in the clinical setting. The Notch signaling pathway has been implicated in different processes of the embryonic neural stem cells (NSCs) during neural tube development. The aim of the present study was to investigate the expression pattern and function of Notch1 (N1) in all‑trans retinoic acid (atRA)‑induced NTDs and NSC differentiation.

Sensitive detection of NO using a compact portable CW DFB-QCL-based WMS sensor.

This paper introduces a compact and portable sensor based on mid-infrared absorption spectroscopy for NO detection employing a room-temperature continuous wave (CW) distributed feedback quantum cascade laser (DFB-QCL) emitting at 1900.08. A software-based digital signal generator and lock-in amplifier, in combination with the wavelength modulation spectroscopy (WMS) technique, were used for the concentration measurement of NO.

CircDHDDS/miR-361-3p/WNT3A Axis Promotes the Development of Retinoblastoma by Regulating Proliferation, Cell Cycle, Migration, and Invasion of Retinoblastoma Cells.

Retinoblastoma (RB) is a common intraocular malignant tumor. The growing evidence has reported that circular RNAs (circRNAs) play critical roles in RB development. Therefore, the purpose of the study is to investigate the regulatory mechanism of circDHDDS in RB.

MiR-208a enhances cell proliferation and invasion of gastric cancer by targeting SFRP1 and negatively regulating MEG3.

The present studies have identified that microRNAs function as regulators in different diseases including cancers. However, the expression patterns and underlying molecular mechanisms of miR-208a involved in gastric cancer (GC) remain little known. In the study, our results demonstrated that miR-208a expression was significantly increased in GC tissues compared with adjacent normal tissues by performing qRT-PCR.

NUSAP1 gene silencing inhibits cell proliferation, migration and invasion through inhibiting DNMT1 gene expression in human colorectal cancer.

Colorectal cancer (CRC) is one of the most common cause of cancer-related death in both female and male patients, with a high capacity for tumor migration and invasion. Recently, aberrant nucleolar and spindle-associated protein 1 (NUSAP1) expression has been reported in several cancers. However, the biological function and molecular mechanism of NUSAP1 in CRC have not been reported.

Lack of ClC-2 Alleviates High Fat Diet-Induced Insulin Resistance and Non-Alcoholic Fatty Liver Disease.

Background/aims: Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease. This study aims to investigate whether chloride channel 2 (ClC-2) is involved in high fat diet (HFD)-induced NAFLD and possible molecular mechanisms.

Methods: ClC-2 expression was liver-specifically downregulated using adeno-associated virus in C57BL/6 mice treated with a chow diet or HFD for 12 weeks.

Long noncoding RNA CCAT2 is activated by E2F1 and exerts oncogenic properties by interacting with PTTG1 in pituitary adenomas.

Pituitary adenomas, arising from the pituitary gland cells, are one of the most frequent tumors found in the sella region. However, the molecular mechanisms involved in the carcinogenesis and progression of pituitary adenomas is still not understood in detail. Long noncoding RNA (lncRNA) colon cancer-associated transcript 2 (CCAT2), a newly identified lncRNA, has been reported to be abnormally expressed in some cancers.

A novel percutaneous achievement and maintenance of reduction and screw fixation for acute displaced scaphoid fractures: minimum two-year follow-up.

Purpose: The purpose of this study was to introduce a novel method of percutaneous achievement and maintenance of reduction for acute displaced scaphoid fractures and evaluate the feasibility of this method in treating acute displaced scaphoid fractures as well as explore its indications.

Methods: From February 2012 to March 2014, 15 patients with acute displaced scaphoid fractures were treated with our technique. Two Kirschner wires were used to achieve and maintain the reduction of the scaphoid fractures throughout the entire process of the traditional percutaneous screw fixation process.

A two-step approach for copper and nickel extracting and recovering by emulsion liquid membrane.

The recycling of copper and nickel from metallurgical wastewater using emulsion liquid membrane (ELM) was studied. P507 (2-ethylhexyl phosphonic acid-2-ethylhexyl ester) and TBP (tributyl phosphate) were used as carriers for the extraction of copper and nickel by ELMs, respectively. The influence of four emulsion composition variables, namely, the internal phase volume fraction (ϕ), surfactant concentration (Wsurf), internal phase stripping acid concentration (Cio) and the carrier concentration (Cc), and the process variable treat ratio on the extraction efficiencies of copper or nickel were studied.

Meta-analysis in the association between obesity and risk of thyroid cancer.

Although many epidemiologic studies have investigated obesity and thyroid cancer risk, definite conclusions cannot be drawn. To clarify the effects of obesity on the risk of thyroid cancer, a meta-analysis was performed. Related studies were identified from PubMed, Springer Link, Ovid, Chinese Wanfang Data Knowledge Service Platform, Chinese National Knowledge Infrastructure (CNKI), and Chinese Biology Medicine (CBM) till 16 Aug 2014.

[Advantage of D2+ lymph node dissection for distal advanced gastric cancer].

Objective: To evaluate the value of D2+ lymph node dissection for patients with distal advanced gastric cancer.

Methods: Clinicopathological data of 305 cases with distal advanced gastric cancer receiving D2+(n=68) or D2(n=237) lymph node dissection in the Tianjin Cancer Hospital from January 2003 to December 2007 were analyzed retrospectively. The overall 5-year survival rate between the 2 groups.

Association between matrix metalloproteinase 1 -1607 1G>2G polymorphism and cancer risk: a meta-analysis including 19706 subjects.

The association between MMP1 -1607 1G>2G polymorphism and cancer risk has been reported, but results remained controversial and ambiguous. To assess the association between MMP1 -1607 1G>2G polymorphism and cancer risk, a meta-analysis was performed. Based on comprehensive searches of the PubMed, Elsevier Science Direct, Excerpta Medica Database (Embase), and Chinese Biomedical Literature Database (CBM), we identified outcome data from all articles estimating the association between MMP1 -1607 1G>2G polymorphism and cancer risk.

Effect of neoadjuvant chemotherapy combined with hyperthermic intraperitoneal perfusion chemotherapy on advanced gastric cancer.

Neoadjuvant and hyperthermic intraperitoneal chemotherapies have been shown to be effective in the treatment of resectable advanced gastric cancer. The aim of the present study was to investigate the clinical efficiency and security of neoadjuvant chemotherapy in combination with hyperthermic intraperitoneal chemotherapy for the treatment of postoperative advanced gastric cancer. A total of 192 patients diagnosed with advanced gastric cancer were randomly divided into the following four groups (n=48 per group): Control, neoadjuvant chemotherapy, hyperthermic intraperitoneal perfusion chemotherapy and joint groups.

Inhibitory effect of biopolymer materials on scar formation following trabeculectomy.

Aim: To investigate the inhibitory effects of amniotic membrane, polylactic acid membrane and chitosan membrane on scar formation following trabeculectomy.

Methods: A total of 24 New Zealand white rabbits (48 eyes) were randomly divided into 4 groups: amniotic membrane group, polylactic acid membrane group, chitosan membrane group, and control group, with 6 rabbits (12 eyes) in each group. The left eyes underwent routine trabeculectomy, and the right eyes were considered as controls.

A new cytotoxic iridoid from Callicarpa nudiflora.

A new iridoid, named nudifloside (1), together with three known compounds, was isolated from the EtOH extract of the aerial parts of Callicarpa nudiflora Hook. The structures were elucidated by a study of their physical and spectral data. Nudifloside (1) and the isolated known compound linearoside (2) displayed inhibitory effects towards chronic myelogenous leukaemia K562 cell line, with IC(50) values of 20.

[Study on chemical constituents and anti-bacterial activity of volatile oil from seed of Aquilaria sinensis].

Volatile oil from the seed of Aquilaria sinensis was extracted with Petroleum ether. Anti-bacterial bioassay of the oil against methicillin-resistant Staphylococcus aureus (MRSA) was carried out by paper disco diffusion method. The result showed that the oil possessed inhibitory activity towards MRSA.