Publications by authors named "Hai-ying Yue"
Article Synopsis
- The study investigates how dose distribution affects the equivalent uniform dose (EUD) model in predicting radiation-induced brain injury in nasopharyngeal carcinoma patients treated with intensity-modulated radiation therapy (IMRT).
- It analyzes data from 103 patients, determining that an optimal volume-effect parameter can be found based on the max area under the curve (mAUC) from receiver operating characteristic (ROC) analyses, revealing that different volumes and dose levels influence predictive accuracy.
- The findings conclude that the volume-effect parameter in EUD varies with dose distribution, and using a critical-dose-volume EUD approach can enhance predictive capabilities compared to traditional dose/volume metrics.
Article Synopsis
- A study analyzed 221 patients with stage IA1-IIA1 cervical cancer to determine if adjuvant radiotherapy is needed after laparoscopic hysterectomy.
- Patients were divided into three groups: those receiving both surgery and radiotherapy (group A), those who had open surgery (group B), and those with laparoscopic surgery alone (group C).
- Results showed that groups A and B had significantly better 3-year local recurrence-free survival rates compared to group C, suggesting that adjuvant radiotherapy improves outcomes for early-stage cervical cancer, especially in stage IB patients.
Injury in Minipig Parotid Glands following Fractionated Exposure to 30 Gy of Ionizing Radiation.
Otolaryngol Head Neck Surg
July 2014
Objective: To explore the effects of 30 Gy of (60)Co γ-rays on apoptosis and reactive oxygen species (ROS) levels in minipig parotid cells as a possible mechanism for radiation-induced parotid injury.
Study Design: Experimental study.
Setting: Department of Radiotherapy, First Affiliated Hospital, Guangxi Medical University, Nanning, China.
[The biological function of peroxiredoxin II on Hep3B cells and its underlying mechanism].
Zhonghua Gan Zang Bing Za Zhi
June 2008
Objectives: To study the biological function and its possible underlying mechanism of peroxiredoxin II (PrxII) in liver cancer cell line Hep3B.
Methods: Two pairs of double-stranded small interfering RNA (siRNA) targeted on PrxII gene were transfected into Hep3B cells using LipofectamineTM 2000. After confirming the inhibited effects of these siRNAs through Quant SYBR Green polymerase chain reaction and Western blot, the biological characters of Hep3B cell were analyzed by flow cytometry analysis, MTT and colony formation assays.
[Changes of beta catenin in carcinogenesis in rat livers induced by aflatoxin B1].
Zhonghua Gan Zang Bing Za Zhi
October 2007
Background & Objective: South Guangxi is an area with high incidence of hepatocellular carcinoma (HCC), and with severe contamination of dietary aflatoxin B1 (AFB1). The activation of beta-Catenin is involved in many cancers. AFB1 may play a key role in hepatocarcinogenesis.
View Article and Find Full Text PDF[The expression of peroxiredoxin II in hepatocellular carcinoma and its significance].
Zhonghua Gan Zang Bing Za Zhi
May 2007
Objective: To evaluate the mRNA and protein expressions of peroxiredoxin II (PrxII) in hepatocellular carcinoma (HCC) and their significance.
Methods: HCC was induced by aflatoxin B1 (AFB1) in 6 tree shrews (Tupaia belangeri chinensis). The expression levels of PrxII mRNA and protein were detected by reverse transcriptase polymerase chain reaction (RT-PCR) and Western blot on HCC tissues and on their surrounding liver tissues (para-HCC).