Publications by authors named "Hai-xin Chen"

A Gram-stain-negative, light khaki, strictly aerobic, rod-shaped, motile via multiple flagella, and catalase- and oxidase-positive bacterium, designated as SSM4.3, was isolated from the seaweed of Gouqi Island in the East China Sea. The novel isolate grows at 0-5.

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A comprehensive multiscale analysis was conducted to explore the effects of different ratios of these materials on its properties. The results show that KC played a crucial role in controlling solution viscosity and gel and sol temperatures. The dissolution time at high water temperatures primarily decreased with an increase in SA content.

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We determined the prevalence and molecular characteristics of -positive () isolated from duck-fish polyculture farms in Guangzhou, China. A total of 914 strains were isolated from 2008 duck and environmental samples (water, soil and plants) collected from four duck fish polyculture farms between 2017 and 2019. Among them, 196 strains were CTX-M-1G-positive strains by PCR, and 177 (90%) -producing strains were -positive.

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Background: Hepatic lipid disorder impaired mitochondrial homeostasis and intracellular redox balance, triggering development of non-alcohol fatty liver disease (NAFLD), while effective therapeutic approach remains inadequate. Ginsenosides Rc has been reported to maintain glucose balance in adipose tissue, while its role in regulating lipid metabolism remain vacant. Thus, we investigated the function and mechanism of ginsenosides Rc in defending high fat diet (HFD)-induced NAFLD.

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Integrated and monoculture freshwater aquaculture systems are often regarded as important reservoirs for antimicrobial resistance genes (ARGs) and antimicrobial resistance bacteria (ARBs), yet only a few studies have assessed differences in the antimicrobial resistome and antibiotic residues between aquaculture modes. In this study, a metagenomic approach was used to comprehensively explore the dynamic patterns and potential transmission mechanisms of ARGs in ducks, human workers, fish, water and sediments during the transition from an integrated to a monoculture freshwater aquaculture mode and to investigate the associations of ARGs with potential hosts in microbial communities using network analysis and a binning approach. The results showed that the abundance and diversity of ARGs were higher under integrated fish-duck farming than in single fish ponds.

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Article Synopsis
  • * The research found that PML levels are significantly higher in fibrotic cardiac tissue and that it influences the activation of fibroblasts when treated with TGF-β1, a factor that promotes fibrosis.
  • * Additionally, the study highlights the interaction between PML and the protein p53, showing that p53 helps regulate PML expression and that PML can protect p53 from degradation, indicating a potential new target for treating cardiac fibrosis.
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Garcinia biflavonoid 1 (GB1) is one of the active chemical components of and is reported to be capable of reducing the intracellular lipid deposition, which is the most significant characteristic of non-alcoholic fatty liver disease. However, its bioactive mechanism remains elusive. In the current study, the lipid deposition was induced in HepG2 cells by exposure to oleic acid and palmitic acid (OA&PA), then the effect of GB1 on lipid metabolism and oxidative stress and the role of regulating PPARα in these cells was investigated.

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Background: Upper gastrointestinal cancers (including oesophageal cancer and gastric cancer) are the most common cancers worldwide. Artificial intelligence platforms using deep learning algorithms have made remarkable progress in medical imaging but their application in upper gastrointestinal cancers has been limited. We aimed to develop and validate the Gastrointestinal Artificial Intelligence Diagnostic System (GRAIDS) for the diagnosis of upper gastrointestinal cancers through analysis of imaging data from clinical endoscopies.

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In order to evaluate the effect of different treatments on yield and greenhouse gas emissions during the summer maize growing season, a two-year film mulching experiment was conducted in 2014 and 2015. In this experiment, the two main experimental factors were rainfed treatment (R) and irrigated treatment (I), and the secondary experimental factors included control treatment (CK), half film mulching treatment (HM), and full film mulching treatment (FM). The emissions of soil greenhouse gases (CO, CH, and NO) were monitored using a static opaque chamber and chromatography method.

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Irrigation can influence greenhouse gas (GHG) emission and carbon footprint in agricultural production. In this study, annual GHG emissions (including CO, CH, and NO) were monitored with static opaque chamber and gas chromatography from a wheat-maize rotation system under different irrigation treatments in the Guanzhong Plain of China during 2014-2015. A total of four different irrigation treatments were conducted, e.

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Objective: To investigate the hereditary tendency of varicocele.

Methods: We included in this study 112 varicocele patients, 117 direct male relatives of the patients, and 100 healthy men as controls. We compared the incidence of varicocele tween the direct relative group and the control group.

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Objective: To investigate the relationship of body mass index with cancer detection on prostate biopsy.

Methods: A total of 168 patients undergoing a prostate biopsy were divided into obese and non-obese groups by BMI ≥ 25 or < 25. Then the differences of prostate-specific antigen (PSA) level, prostate volume, prostate cancer detection rate and pathology result between two groups.

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Objective: To evaluate the diagnostic usefulness of serum osteoprotegerin (OPG) in prostate cancer bone metastasis.

Methods: Serum osteoprotegerin were measured by ELISA assay in 30 healthy men, 30 patients with benign prostatic hyperplasia, 66 patients with prostate cancer including 36 without bone metastasis (30 with localized cancer, 6 with lymph node metastasis) and 30 with bone metastasis. The results associated with clinical data were calculated statistically.

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