Umbilical cord-derived mesenchymal stem cell transplantation combined with hyperbaric oxygen treatment for repair of traumatic brain injury.

Transplantation of umbilical cord-derived mesenchymal stem cells (UC-MSCs) for repair of traumatic brain injury has been used in the clinic. Hyperbaric oxygen (HBO) treatment has long been widely used as an adjunctive therapy for treating traumatic brain injury. UC-MSC transplantation combined with HBO treatment is expected to yield better therapeutic effects on traumatic brain injury.

Expression of bone-related genes in bone marrow MSCs after cyclic mechanical strain: implications for distraction osteogenesis.

Aim: Understanding the response of mesenchymal stem cells (MSCs) to mechanical strain and their consequent gene expression patterns will broaden our knowledge of the mechanobiology of distraction osteogenesis.

Methodology: In this study, a single period of cyclic mechanical stretch (0.5 Hz, 2,000 microepsilon) was performed on rat bone marrow MSCs.

[Correction of the epicanthal fold and angulus oculi using the Z-epicanthoplasty].

Objective: To explore a new procedure for aesthetic correction of the medial epicanthal fold aim at the etiopathogenesis.

Methods: The new Z-epicanthoplasty devise the upper and inferior margin of angle of eye medial as one angle of the Z.

Results: From 2004 to 2006, 129 patients were treated by using the method.

[Effects of mesenchymal stem cells transplantation on cranial suture distraction osteogenesis in growing goats].

Objective: To observe the effects of mesenchymal stem cells (MSCs)on cranial suture under mechanical strain in growing goats.

Methods: 10 growing goats were used in this study. A customized distractor was used for distraction of the coronal suture at a rate of 0.

Autogenous coronoid process as a new donor source for reconstruction of mandibular condyle: an experimental study on goats.

Objective: To evaluate the feasibility and effectiveness of autogenous coronoid process grafts for reconstruction of the mandibular condyle.

Study Design: Two groups of 9 goats each were used. Each animal underwent unilateral total condyle and disk removal and was treated by grafting an autogeneous coronoid process.

[Construction of recombinant plasmid pEGFP-BMP7 and its expression in rat bone marrow mesenchymal stem cells in vitro].

Objective: To construct recombinant plasmid pEGFP-BMP7 and determine its expression in rat bone marrow mesenchymal stem cells (MSCs) in vitro.

Methods: cDNA of target gene was obtained from neonatal rat kidney by RT-PCR. After sequencing the target gene, the cDNA was subcloned into a eukaryote plasmid pEGFP-N1 by directed cloning and then digested with two restrictive endonucleases to verify the correctiveness of the recombinant plasmid pEGFP-BMP7.