Publications by authors named "Hai-rong Zhang"

Article Synopsis
  • Researchers successfully created axially chiral C2-arylquinoline through an asymmetric reaction involving alkynes, using chiral phosphoric acid as a catalyst, achieving high yields and enantioselectivity.
  • The study outlines a detailed reaction mechanism divided into key steps: hydrogen transfer, C-N bonding, annulation, and dehydration, with multiple potential pathways for each step.
  • Theoretical analyses, including QTAIM and IGMH, clarified the influence of weak intermolecular interactions and provided insights into enantioselectivity, with theoretical calculations aligning well with experimental outcomes.
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Article Synopsis
  • - The study explores the reaction between sodium (Na) and hydrogen fluoride (HF), which forms sodium fluoride (NaF) and hydrogen gas, highlighting the formation of specific complexes during the reaction process.
  • - Detailed mechanisms are investigated, revealing that sodium initially interacts with HF to create a complex, leading to a transition state and subsequent bond formation, ultimately resulting in various complexes involving NaF and HF.
  • - Analyses like noncovalent interaction (NCI), quantum theory of atoms in molecules (QTAIM), and natural bond orbital (NBO) are used to understand the interactions within these complexes, enhancing our knowledge of the reactions between sodium and hydrogen fluoride.
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The efficient and economical removal of fermentation inhibitors from the complex system of biomass hydrolysate was one of the basics and keys in bio-chemical transformation. In this work, post-cross-linked hydrophilic-hydrophobic interpenetrating polymer networks (PMA/PS_pc IPNs and PAM/PS_pc IPNs) were proposed to remove fermentation inhibitors from sugarcane bagasse hydrolysate for the first time. PMA/PS_pc and PAM/PS_pc IPNs can obviously enhance the adsorption performance towards fermentation inhibitors due to their higher surface area and hydrophilic-hydrophobic synergetic surface properties, especially PMA/PS_pc IPNs has higher selectivity coefficients of 4.

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China has regulated its hepatitis B vaccination policy. However, data on the prevalence of hepatitis B virus (HBV) infection have not been updated since 2014. In addition, the impact of the policy on awareness of hepatitis B is limited, especially in Fujian Province where HBV infection is highly prevalent.

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LncRNA-cCSC1 is highly expressed in colorectal cancer (CRC). The study was designed to evaluate the function and mechanism of lncRNA-cCSC1 in cell proliferation of CRC. RT-PCR was used to measure the expression levels of lncRNA-cCSC1 in CRC cell lines.

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Economical removal of fermentation inhibitors from lignocellulosic hydrolysate plays a considerable role in bioconversion of lignocellulose biomass. In this work, the textural properties of polyacrylamide/polystyrene interpenetrating polymer networks (PAM/PS IPNs) on adsorption of fermentation inhibitors from sugarcane bagasse hydrolysate (SCBH) were investigated for the first time. The results showed that, the specific surface area, pore diameter and surface polarity had important influence on its adsorption performance towards sugars, organic acids, furans and acid-soluble lignin.

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The photoelectric conversion efficiency of perovskite solar cells has improved rapidly, but their stability is poor, which is an important factor that restricts their commercial production. This paper studies the physical and chemical stability of perovskite solar cells based on first principles. It is well known that methylamido lead iodide compounds and methylamino lead iodide compounds are easily degraded into NHCH[double bond, length as m-dash]NHI, CHNHI and PbI.

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Cellulose-based superabsorbent was synthesized by bacterial cellulose (BC) grafting acrylic acid (AA) in the presence of ,'-methylenebisacrylamide (NMBA) as a crosslinker and ammonium persulfate (APS) as an initiator. The influence of different factors on composite synthesis, including the weight ratio of the monomer to BC, initiator content, crosslinker content, AA neutralization degree, reaction temperature, and reaction time on the water absorbency of the composite, were systematically learned. Under the optimized conditions, the maximum water absorbency of the composite was 322 ± 23 g/g distilled water.

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Purpose: To explore whether the modified-nutrition index (m-NI) is a prognostic factor for the overall survival (OS) in nasopharyngeal carcinoma (NPC) patients who undergo intensity-modulated radiotherapy (IMRT).

Methods: Clinical data were prospectively collected from NPC patients who underwent IMRT at our hospital between October 2008 and December 2014. The patient nutritional status before radiotherapy was evaluated using the m-NI, based on eight nutrition indicators including body mass index, arm muscle circumference, albumin, total lymphocyte count, red blood cell count, hemoglobin, serum pre-albumin, and transferrin.

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Lumping kinetics models were built for the biological treatment of acetone-butanol-ethanol (ABE) fermentation wastewater by oleaginous yeast Trichosporon cutaneum with different fermentation temperatures. Compared with high temperature (33°C, 306 K) and low temperature (23°C, 296 K), medium temperature (28°C, 301 K) was beneficial for the cell growth and chemical oxygen demand (COD) degradation during the early stage of fermentation but the final yeast biomass and COD removal were influenced little. By lumping method, the materials in the bioconversion network were divided into five lumps (COD, lipid, polysaccharide, other intracellular products, other extracellular products), and the nine rate constants (k-k) for the models can well explain the bioconversion laws.

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Article Synopsis
  • The study investigates the elastic properties and thermodynamics of a newly synthesized material called -CN under high temperature and pressure using first-principles calculations.
  • The findings confirm agreement with previous experimental and theoretical data, showing notable elastic anisotropy in -CN, with varying stiffness along different crystal orientations.
  • Key thermal properties such as Debye temperature, heat capacity, and thermal expansion were also analyzed within the pressure range of 0-90 GPa and temperature up to 1600 K.
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A new iron(III) complex (1) of 5-nitro-8-hydroxylquinoline (HNOQ) was synthesized and structurally characterized in its solid state and solution state by IR, UV-Vis, electrospray ionization (ESI)-MS, elemental analysis, conductivity and X-ray single crystal diffraction analysis. The DNA binding study suggested that complex 1 interacted with calf thymus (ct)-DNA mainly via an intercalative binding mode. By 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay, the in vitro cytotoxicity of complex 1, comparing with HNOQ and cisplatin, was screened towards a series of tumor cell lines as well as the normal liver cell line HL-7702.

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Bacterial cellulose (BC) has great potential to be used as a new filler to reinforce isotactic polypropylene (iPP) due to its high crystallinity, biodegradability, and efficient mechanical properties. In this study, esterification was used to modify BC, which improved the surface compatibility of the iPP and BC. The results indicated that the cellulose octoate (CO) changed the surface properties from hydrophilic to lipophilic.

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To evaluate the possibility of Bacterial cellulose/Inorganic Gel of Bentonite (BC/IGB) composite production using in situ method, the BC/IGB composite was successfully produced by in situ modification of BC in both HS medium and corncob hydrolysate. The results showed that the BC/IGB composite obtained in HS medium (one classical medium for BC production) had a higher water holding capacity, but the water retention capacity of the BC/IGB composite obtained in corncob hydrolysate was better. The performance of BC/IGB composite depended on the environment of in situ modification.

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We aimed to assess the effect of chemoradiotherapy on the nutritional status of patients with nasopharyngeal cancer (NPC) and to detect the risk factors for poor nutrition status in NPC patients after radiotherapy. A total of 104 NPC patients participated in this clinical observational study. Psychological distress and nutritional indicators were measured prior to chemoradiotherapy.

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In this study, corncob acid hydrolysate was used as a substrate for bacterial cellulose (BC) production by Gluconacetobacter xylinus. After 2 weeks' static fermentation, a BC yield of 4 g/L could be obtained. Both effects of medium composition and fermentation condition on the BC production were evaluated.

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Purpose: This study was designed to detect the prevalence of poor sleep quality in cervical cancer patients before and after adjuvant therapy, determine whether the prevalence of poor sleep quality in cervical cancer patients is higher than that in the general population, and analyze the factors associated with poor sleep quality.

Methods: A total of 76 stages I and II cervical cancer patients and 116 female residents completed the Pittsburgh Sleep Quality Index (PSQI). Patient Neurotoxicity Questionnaire (PNQ), Distress Thermometer (DT), Multidimensional Fatigue Inventory, and Hospital Anxiety and Depression Scale were used to measure the patients' chemotherapy-induced peripheral neurotoxicity (CIPN), psychological distress, fatigue, anxiety, and depression.

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In 2013, the World Health Organization reported the first case of human infection with a new influenza A (H7N9) virus in China. This has caused damage and panic within certain areas in China. Therefore, analysis of this virus with bioinformatics technology is very necessary.

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For the ultrasonic normally-incident reflected method, the phase shift of the mid-layer in a multi-layered structure has been theoretically derived and expressed as a sum form of the measured phase shift and the crossing phase shift. Using the sum form, the characteristics of phase shifts of a linear-viscoelastic layer on the two different elastic substrates of half-space of the infinite extent are first analyzed. By the replacement of phase shift of the upper elastic substrate with the corresponding measured phase shift, the substitution function of the input acoustical impedance of a next inaccessible layer has been developed.

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Article Synopsis
  • - The study investigated how catechin interacts with bovine serum albumin (BSA) using fluorescence quenching and FTIR spectroscopy, focusing on binding constants and mechanisms at physiological conditions.
  • - Catechin was found to effectively quench BSA's intrinsic fluorescence through a static quenching mechanism, with binding constants indicating a strong affinity at different temperatures.
  • - The interaction is primarily influenced by hydrophobic and electrostatic forces, and catechin binds to site I of BSA, causing changes in BSA's secondary structure as shown by FTIR analysis.
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The interaction of two kinds of sulfated chitosans with DNA was investigated using fluorescence spectra, absorption spectra, alkaline denaturation curves, ionic strength, fluorescence quenching etc. The results showed that there were two modes of the interaction between sulfated chitosans and DNA/ ethidium bromide (EB): intercalative and electrostatic binding. Hyperchromic and bathochromic effects in the absorption spectra were observed when sulfated chitosans with a low degree of substitution (CT-L) or a high degree of substitution (CT-L) were bound to herring sperm DNA.

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Objective: To evaluate the efficacy and safety of Dinggui Oil Capsule in treating irritable bowel syndrome (IBS) with stagnation of qi and cold.

Methods: A prospective, randomized, placebo-controlled, double-blind clinical study was undertaken. One hundred and ninety-eight patients with IBS and syndrome of stagnation of qi and cold were randomly divided into high-dose Dinggui Oil group (DGO-H, 1.

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A natural product, sorghum pigment, consists of a number of important flavonoid derivatives, occurrs on the seed capsules or in the stems of many sorghums, and is widely applied in different fields of food, cosmetic and dyeing industries, It is important for scavenging hydroxyl free radicals and protection of human healthiness. Scavenging capacities of hydroxyl free radicals with sodium nitrite, quercetin and sorghum pigment were comparatively researched by fluorimetry, and the model of hydroxyl free radicals produced is based on the reaction of Cu2+ -catalyzed oxidation of ascorbic acid in the presence of hydrogen peroxide. The hydroxyl radicals react with benzoic acid, forming a fluorescent product, and the fluorescence intensity was determined by the concentration of hydroxybenzoic acid.

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The aim of the present work is to study the role of polyaccharide and flavone compounds of Flos lonicerae, Ganoderma lucidum etc. in protecting DNA with EB as a probe to determine the fluorescence integration intensity of DNA and EB mixture. D is defined as the interaction constant between different extracts from traditional Chinese herbs and DNA.

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