Aim: To investigate the effect of secondary lymphoid tissue chemokine (SLTC) and its receptor CCL21/CCR7 on chemotaxis of peripheral blood lymphocytes in the patients with Sjögren's syndrome (SS) and explore their roles in the SS pathogenesis.
Methods: Thirty-one SS patients were selected, including 18 primary SS patients (pSS) and 13 secondary SS (sSS) patients. In addition, 20 healthy persons were selected as normal controls.