Long-term effect of hospital volume on the postoperative prognosis of 158,618 patients with esophageal squamous cell carcinoma in China.

Background: The impact of hospital volume on the long-term survival of esophageal squamous cell carcinoma (ESCC) has not been well assessed in China, especially for stage I-III stage ESCC. We performed a large sample size study to assess the relationships between hospital volume and the effectiveness of ESCC treatment and the hospital volume value at the lowest risk of all-cause mortality after esophagectomy in China.

Aim: To investigate the prognostic value of hospital volume for assessing postoperative long-term survival of ESCC patients in China.

Increases prognostic value of clinical-pathological nomogram in patients with esophageal squamous cell carcinoma.

Background: This study was intended to construct a brand new prognostic nomogram after combine clinical and pathological characteristics to increases prognostic value in patients with esophageal squamous cell carcinoma.

Methods: A total of 1,634 patients were included. Subsequently, the tumor tissues of all patients were prepared into tissue microarrays.

Occupational health effect of TCE exposure: Experiment evidence of gene-environment interaction in hypersensitivity reaction.

Background: Recently, Trichloroethylene (TCE) induced TCE hypersensitivity syndrome (THS) has attracted the attention of many researchers in the field of environmental and occupational health. Studies have revealed that Human leukocyte antigen (HLA) polymorphisms were the important genetic determinants of the diseases, but the potential molecular mechanism remains unclear.

Objective: This study aimed to investigate the association between THS and HLA at the molecular level.

Characterization of E-cadherin expression in normal mucosa, dysplasia and adenocarcinoma of gastric cardia and its influence on prognosis.

Background: Gastric cardia adenocarcinoma (GCA), which has been classified as type II adenocarcinoma of the esophagogastric junction in western countries, is of similar geographic distribution with esophageal squamous cell carcinoma in China, and even referred as "sister cancer" by Chinese oncologists. The molecular mechanism for GCA is largely unknown. Recent studies have shown that decreased expression of E-cadherin is associated with the invasion and metastasis of multiple cancers.

and expression and association with the prognosis in esophageal squamous cell carcinoma.

We investigated whether and were related to esophageal squamous cell carcinoma (ESCC). ESCC microarray datasets and reverse transcriptase qualitative PCR were used to analyze and expression. The GSE120356 and GSE33810 datasets identified and as the candidates and and expression was downregulated in ESCC.

Predictors of mortality for patients with COVID-19 pneumonia caused by SARS-CoV-2.

https://bit.ly/336rv2Y

piR-823 demonstrates tumor oncogenic activity in esophageal squamous cell carcinoma through DNA methylation induction via DNA methyltransferase 3B.

Piwi-interacting RNAs (piRNAs) dysregulation occurs frequently in extensive cancers. However, there was no report about piRNA expression in esophageal cancer (EC). In this study, the expression levels of piR-823 and DNMT1, DNMT3A, DNMT3B were detected in 54 pairs of ESCC tissues and adjacent normal tissues using the quantitative real-time polymerase chain reaction method.

Treatment Status of Elderly Patients With Severe Mental Disorders in Rural China.

This study was performed to compare the treatment status between older (≥65 years) and younger adults (18-64 years) with severe mental illness (SMI) and explore factors associated with treatment status in rural China. Persons with SMI were identified in one mental health survey in 2015 in 6 townships of Xinjin County, Chengdu, China. Logistic regressions were conducted to explore factors associated with treatment status.

[Pollen in surface soil at the southern slope of western Tianshan, China.].

We analyzed 52 pollen samples of surface soils from the southern slope of western Tian-shan, China, to understand the relationship between the surface pollen and modern vegetation, and the significance of the Artemisia/Chenopodiaceae (A/C). The results showed that there were five vegetation zones from the mountain top to the foot, i.e.

Decreased expression of SPINT1-AS1 and SPINT1 mRNA might be independent unfavorable prognostic indicators in esophageal squamous cell carcinoma.

The serine peptidase inhibitor, Kunitz type 1 antisense RNA1 (), a long non-coding RNA , has been linked to cancer progression. In this study, we aimed to explore the expression in matched esophageal squamous cell carcinoma (ESCC) and normal tissues, and analyze the potential correlations of expression with clinicopathological characteristics, in order to evaluate its prognosis and therapeutic value. SPINT1-AS1 expression was detected in 99 cases of matched ESCC and normal tissues samples using the quantitative real-time polymerase chain reaction method.

High expression of HLA-DQA1 predicts poor outcome in patients with esophageal squamous cell carcinoma in Northern China.

Background: Our previous studies demonstrate that the major histocompatibility complex (MHC) is associated with the progression of esophageal squamous cell carcinoma (ESCC). HLA-DQA1, which belongs to the MHC Class II family, may be a potential biomarker in ESCC progression. However, the association between HLA-DQA1 and ESCC in high-incidence area of northern China has not been well characterized.

Morphological Type Identification of Self-Incompatibility in and Its Phylogenetic Evolution Pattern.

Self-incompatibility (SI) is a type of reproductive barrier within plant species and is one of the mechanisms for the formation and maintenance of the high diversity and adaptation of angiosperm species. Approximately 40% of flowering plants are SI species, while only 10% of orchid species are self-incompatible. Intriguingly, as one of the largest genera in Orchidaceae, 72% of species are self-incompatible, accounting for nearly half of the reported SI species in orchids, suggesting that SI contributes to the high diversity of orchid species.

[Relationship between leaf litter decomposition and colonization of benthic macroinvertebrates during early frost period in a headwater stream in the Changbai Mountains, Northeast China].

Annually, about 70% of the streams in the Changbai Mountains are frosted during November to April, with manifest seasonal freeze-thaw characters. By using monoculture and mixing leaf litters of Tilia amurensis, Acer mono and Quecus mongolica, this research attempted to disentangle the relationship between leaf litter decomposition and colonization of macroinvertebrates in the stream during early frost period. A 35-day investigation was carried out in a headwater stream of the Changbai Mountains.

Truth telling for patients with esophageal squamous cell carcinoma in Henan, China.

Objective: : This study aims to investigate the truth-telling status and the relevant factors of esophageal squamous cell carcinoma (ESCC) patients in Henan, China.

Methods: : A cross-sectional study from April to June 2015 using questionnaires was given to 301 family members of hospitalized ESCC patients based in three affiliated hospitals of Zhengzhou University (i.e.

The Dendrobium catenatum Lindl. genome sequence provides insights into polysaccharide synthase, floral development and adaptive evolution.

Orchids make up about 10% of all seed plant species, have great economical value, and are of specific scientific interest because of their renowned flowers and ecological adaptations. Here, we report the first draft genome sequence of a lithophytic orchid, Dendrobium catenatum. We predict 28,910 protein-coding genes, and find evidence of a whole genome duplication shared with Phalaenopsis.

[Isolation, Identification of a p-tert-Butylcatechol-Degradaing Strains and Optimization for Its Degradation by Response Surface Methodology].

A bacterial strain YHl that used p-tert-Butylcatechol (TBC) as the sole carbon and energy source was isolated from the activated sludge of the wastewater treatment plant of a chemical factory. The strain was identified as Pseudomonas corrugate by morphological characteristics, physiological and biochemical properties, BIOLOG and the 16S rDNA sequence analysis. The degration rate of TBC was above 82% with an initial concentration of 500 mg.

Association of the MS4A2 gene promoter C-109T or the 7th exon E237G polymorphisms with asthma risk: a meta-analysis.

Background And Objective: A large number of studies have examined the association between the Membrane-spanning 4 domains, superfamily A, number 2 (MS4A2) gene C-109T (rs1441586) or E237G (rs569108) variants and asthma risk. However, the results are inconsistent and inconclusive. To derive a more precise estimation, a meta-analysis was performed.

Association between the interleukin-4 gene C-589T and C+33T polymorphisms and asthma risk: a meta-analysis.

Background And Aims: A large number of studies have investigated the correlation between the interleukin (IL)-4 C-589T and C+33T polymorphisms and asthma susceptibility. However, the results are inconsistent. The objective of this study is to explore the association between the IL-4 C-589T and C+33T polymorphisms and asthma risk using meta-analysis.

[Effect of iptkalim on myocardial enzymes and free radicals metabolism with hypoxic pulmonary hypertension].

Objective: To explore the effects of iptkalim on myocardial enzymes and free radicals metabolism with hypoxic pulmonary hypertension (HPH), in order to provide evidence for the mechanism of iptkalim on clinical treat.

Methods: 110 young men stayed at high altitude above 5 000 m were divided into iptkalim group (n = 74) and placebo group (n = 36), aminotransferase (ALT), aspartate aminotransferase (AST), gamma-glutamyltransferase (gamma-GT), creatine kinase (CK), lactate dehydrogenase (LDH), superoxide dismutase (SOD), malonaldehyde (MDA), nitric oxide(NO) and nitric oxide synthase(NOS) were detected before and after took medicines for 6 mouths.

Results: After took medication for 6 mouths, ALT, AST, gamma-GT, CK and LDH were reduced, SOD, NO, and NOS were increased, MDA were reduced, there were very significant difference (P < 0.

Evaluation of relative water use efficiency (RWUE) at a regional scale: a case study of Tuhai-Majia Basin, China.

Enhancing water use efficiency (WUE) is the key approach to maintain sustainable water resource supply. Due to the complexity of the water cycle, accurate estimation of WUE at the regional scale is a challenging task. Here we presented a framework of relative water use efficiency (RWUE).

[Analysis of membrane fouling genesis in nanofiltration process for advanced treatment of dyeing and finishing wastewater].

In order to investigate the types and genesis of membrane fouling of nanofiltration desalination system treating dyeing and finishing wastewater of cotton knit textile, comprehensive analysis, using ICP-AES, SEM-EDX, FTIR, TGA, high optical microscope and XRF, was carried out based on tests of influent water quality, and tests of the membrane fouling states of different processes and tests of membrane cleaning. The results showed that the types of membrane fouling included inorganic fouling, organic fouling and microbial fouling. The mass percents of bound water, organic substance and inorganic substance of dry foulants, dried at 105 degrees C, were 8.

[Hypermethylation of O(6)-methylguanine-DNA methyltransferase in human bronchial epithelial cell induced by organic extracts of coke oven emissions].

Objective: To elucidate the mechanism of carcinogenesis induced by coke oven emissions by investigating the cell genetic damage index and the methylation of O⁶-methylguanine-DNA methyltransferase (MGMT).

Methods: The human bronchial epithelial cell 16HBE was treated by 1 µmol/L B(a)P for 48 h, and then was exposed continuously to either 1‰ dimethyl sulfoxide (DMSO) or organic extracts of coke oven emission (OE-COE) for five days at the concentrations of 0, 2.5, 5.