Publications by authors named "Hai-fang Zhang"

Article Synopsis
  • * She underwent a combination of chemotherapy and immunotherapy, specifically the XELOX regimen with tislelizumab, leading to the complete disappearance of liver metastases and significant shrinkage of the primary tumor.
  • * Following a successful laparoscopy and radical total gastrectomy, which showed no remaining cancer, the patient now receives ongoing treatment to address any potential residual disease, showcasing the effectiveness of combining immunotherapy with traditional chemotherapy in advanced cancer cases.
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  • Soil biodiversity is important for farming and the environment, and cover crops can help improve soil health.
  • Different numbers of cover crop species affect weeds and the types of tiny worms called nematodes in the soil, with more species leading to fewer weeds.
  • More diverse cover crops (like 4 or 8 species) help increase beneficial nematodes and improve soil nutrients, making the ecosystem healthier.
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Following the publication of this paper, it was drawn to the Editors' attention by a concerned reader that the western blotting data shown in Fig. 3C were strikingly similar to data appearing in different form in another article by different authors at a diferent research institute. Owing to the fact that the contentious data in the above article were already under consideration for publication prior to its submission to , the Editor has decided that this paper should be retracted from the Journal.

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  • The study focuses on how standardized cancer pain management affects lung cancer patients with bone metastasis in China.
  • It compares two groups: one receiving conventional pain management and the other receiving standardized pain management, analyzing demographics, pain relief, and satisfaction levels.
  • Results show that patients in the standardized group experienced greater pain relief and higher satisfaction, highlighting the benefits of consistent pain management strategies.
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Aims: This study aims to compare the proportion of peripheral blood T lymphocyte subsets and related blood cell and bone marrow cytology indexes between patients with aplastic anemia (AA) and hypoplastic myelodysplastic syndrome (hypo-MDS), and investigate the clinical identification significance.

Materials And Methods: A total of 41 patients with AA and 46 patients with hypo-MDS were collected, and the proportions of peripheral blood T lymphocyte subsets, CD3CD16/CD56NK cells, CD3CD57T-LGL cells and CD19B lymphocytes were detected by flow cytometry.

Key Findings: The CD4/CD8 ratio decreased in the AA and hypo-MDS groups, and the difference was statistically significant when compared with that in the control group (P<0.

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Angiogenesis, the formation of new blood vessels from preexisting endothelium, is a process that involves a series of interassociated and mutually interactive pathophysiological processes. It is accepted that microRNAs (miRNAs) regulate endothelial cell behavior, including their involvement in angiogenesis. However, it remains unclear whether miRNAs are involved in the regulation of angiogenesis following cerebral ischemia.

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Ocular toxocariasis is caused by migration of a Toxocara larva through the posterior eye. We report the first case of pediatric ocular toxocariasis caused by T. canis in Jiangsu Province, eastern China.

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Objective: To study the antiproliferation effect on HepG2 cells and its underlying mechanism of the active chemical composition of the Viburnum Odoratissimum.

Methods: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) reduction assay and trypan blue dye exclusion assay were used to assess the effect of vibsane-type diterpenoids on the proliferation of various tumor cells. Alterations in cell cycle and apoptosis were determined by flowcytometry.

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By using polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) and sequence analysis, this paper studied the nifH gene diversity and community structure of soil nitrogen-fixing microbes in Hulunbeier sandy land of Inner Mongolia under four years management of five vegetation restoration modes, i. e., mixed-planting of Agropyron cristatum, Hedysarum fruticosum, Caragana korshinskii, and Elymus nutans (ACHE) and of Agropyron cristatum and Hedysarum fruticosum (AC), and mono-planting of Caragana korshinskii (UC), Agropyron cristatum (UA), and Hedysarum fruticosum (UH), taking the bare land as the control (CK).

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This paper reports the diagnosis and treatment of one patient infected with Thelazia callipaeda, which suggests that in the diagnosis, the ophthalmologists should combine the epidemiological contact history with the examination so as to avoid misdiagnosis.

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Objective: To evaluate the clinical efficiency of tanshinone IIA-sulfonate (STS) in the treatment of liver fibrosis of advanced schistosomiasis.

Methods: A total of 73 advanced schistosomiasis patients were selected into a treatment group and 55 cases of advanced schistosomiasis were selected into a control group, and dipstick dye immunoassay assay (DDIA) for schistosomiasis and HBsAg of all the patients were negative. The patients in the treatment group received STS for 14 days, and all the patients in both groups received the conventional liver-protecting treatment for 14 days.

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Article Synopsis
  • The study aimed to identify and quantify EGFR gene mutations in lung cancer tissues, comparing the efficacy of a new real-time PCR method (ADx-EGFR kit) to traditional Sanger sequencing.
  • A total of 208 tumor samples were analyzed, with Sanger sequencing successfully identifying mutations in 11.2% of cases, while the ADx-EGFR method detected mutations in 19.2% of samples.
  • Results indicated that the ADx-EGFR real-time PCR method had a significantly higher success rate and mutation detection capability than Sanger sequencing, proving it to be a more effective clinical tool for lung cancer screening.
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Background: De novo malignancies are serious complications in the late postoperative period after liver transplantation. The most common de novo tumors are skin malignancies, posttransplantation lymphoproliferative disorder, tumors of the head and neck, and Kaposi's sarcoma. Such posttransplant de novo malignancies are apparently rarely found in bone.

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Objective: To study the effect of enteral nutrition (EN) on dextran sulfate sodium (DSS)-induced colitis in rats.

Methods: Eighty-four Sprague-Dawley rats were divided into 7 groups (12 rats in each group). The blank control group was given ordinary laboratory feed and drinking water.

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Aim: To evaluate the peroxynitrite (ONOO(-)) of puerarin on retinal pigment epithelial (RPE) cells apoptosis induced partly by peroxynitrite via Fas/FasL.

Methods: RPE cells from C57BL/6 mice eyes were cultured. Diabetes was induced in Sprague-Dawley (SD) rats by streptozotocin (STZ) intraperitoneal injection.

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