Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
January 2008
Objective: To investigate the effect of high mobility group box-1 protein (HMGB1) on immune function of human T lymphocytes in vitro and explore its potential role in cell-mediated immune dysfunction.
Methods: Fresh blood was obtained from healthy adult volunteers and peripheral blood mononuclear cells (PBMCs) were isolated, then rhHMGB1 was added to PBMCs. Cell viability was assessed by thiazolyl blue (MTT) assay.
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
February 2006
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
January 2006
Objective: To investigate the effects of Xuebijing injection on multiple organ dysfunction and mortality in rats with delayed resuscitation after scald injury.
Methods: Wistar rats were subjected to a 30% total body surface area (TBSA) full-thickness scald injury in the experimental groups. One hundred and thirty male Wistar rats were randomly divided into sham scald group (n=10), thermal injury group (n=60, 40 ml/kg normal saline was infused peritoneally 6 hours postburn), and Xuebijing treatment group (n=60, 4 ml/kg Xuebijing injection was injected twice a day in addition to delayed resuscitation).
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
August 2005
Objective: To propose a guideline of respiratory support for emergency patients.
Methods: To summarize the experiences gained in giving stepwise respiratory support (SRS) in 2,548 patients for emergency care (including 1,823 trauma patients and 725 non-trauma patients) between 1992 to 2002.
Results: There were 1,876 male and 672 female patients with the ratio of male to female 2.
Zhongguo Wei Zhong Bing Ji Jiu Yi Xue
July 2005
Objective: To investigate the effect of intensive insulin therapy on serum levels of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6) and C reaction protein (CRP), all of which reflected the inflammatory status in patients with severe trauma.
Methods: Forty patients with severe trauma [injury severity score (ISS)>or=20] were randomly divided into intensive insulin therapy group and control group. Enzyme-linked immunoadsorbent assay (ELISA) method was used to determine the TNF-alpha and IL-6 levels within 72 hours after admission.