Publications by authors named "Hai-cheng Yang"
Alveolar echinococcosis is a zoonotic disease that seriously endangers human health. This study aims to investigate the effects of osteopontin on the growth and intra- or extra-hepatic metastasis of Echinococcus multilocularis. Mice were randomly divided into untreated (control group, n = 25), PBS (n = 25), Lv3-NC (n = 25), and Lv-OPN-734 (n = 25) groups.
View Article and Find Full Text PDFHP-β-CD-PLGA nanoparticles improve the penetration and bioavailability of puerarin and enhance the therapeutic effects on brain ischemia-reperfusion injury in rats.
Naunyn Schmiedebergs Arch Pharmacol
January 2013
Article Synopsis
- Puerarin can help reduce brain damage from ischemia-reperfusion injury, but it struggles to cross the blood-brain barrier due to its properties.
- Researchers created puerarin-loaded nanoparticles with the help of HP-β-CD and gelatin to enhance its solubility and entrapment in the brain.
- The study found that these nanoparticles significantly reduced brain infarction and improved brain function recovery compared to traditional puerarin treatments.