Publications by authors named "Hai-Zi Zheng"
J Phys Chem B
February 2009
Article Synopsis
- The study used magnetic tweezers and atomic force microscopy to investigate how the cationic surfactant C12 C6 C12 Br2 causes DNA to condense in a stepwise manner, with each event reducing DNA length by around 100 nm at forces between 0.5 and 4 pN.
- Higher stretching forces (above 6 pN) can reverse this process, releasing approximately 60 nm of DNA in a similar stepwise fashion.
- The findings suggest a new model of DNA condensation involving the formation of independent beadlike structures that pack into denser configurations, resembling behavior observed in chromatin assembly.
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