Image registration between planning CT images and cone beam-CT (CBCT) images is one of the key technologies of image guided radiotherapy (IGRT). Current image registration methods fall roughly into two categories: geometric features-based and image grayscale-based. Mutual information (MI) based registration, which belongs to the latter category, has been widely applied to multi-modal and mono-modal image registration.
View Article and Find Full Text PDFObjective: To compare the clinical efficacy and safety of two chemotherapy regimens for concurrent chemoradiotherapy in patients with stage Ib2 to IVa squamous cell carcinoma of the uterine cervix.
Methods: Between November 2007 and November 2011, 146 patients with stage Ib2 to IVa squamous cell carcinoma of the uterine cervix who received concurrent chemoradiotherapy in Peking University Cancer Hospital were analyzed. All cases were divided into two groups according to the different chemotherapy regimens during radiation therapy, the group receiving radiotherapy concomitant with weekly cisplatin or nedaplatin alone (platinum alone group, n = 59), the group receiving radiotherapy concomitant with cisplatin plus fluorouracil or nedaplatin plus tegafur every 3 weeks (combined group, n = 87).