[Significance of calcineurin activation and CD40L expression in patients with active lupus nephritis].

Aim: To investigate the significance of the calcineurin (CaN) activation in active lupus nephritis patient.

Methods: Peripheral blood mononuclear cells (PBMCs) were separated from twenty-one active LN patients and 12 healthy controls. Phosphatase activity of CaN was determined using the CaN assay kit by measuring the content of released PO4.