Hepatic Steatosis Aggravates Vascular Calcification via Extracellular Vesicle-Mediated Osteochondrogenic Switch of Vascular Smooth Muscle Cells.

The global incidence of metabolic dysfunction-associated fatty liver disease (MAFLD) has risen sharply. This condition is strongly associated with the risk of cardiovascular disease (CVD), but how MAFLD affects the development and progression of CVD, particularly concerning vascular calcification, remains unclear. Herein, extracellular vesicles (EVs) are identified from steatotic hepatocytes as a trigger that accelerated the progression of both vascular intimal and medial calcification.

Serum procalcitonin as a marker of neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD).

Background: Neonatal Intrahepatic Cholestasis (NICCD), as the early-age stage of Citrin deficiency involving liver dysfunction, lacks efficient diagnostic markers. Procalcitonin (PCT) has been identified as a biomarker for infection as well as various organ damage. This study aimed to explore the potential of PCT as a biomarker for NICCD.

Functional Characterization of the Gene and Its Promoter from Cassava.

Soluble starch synthases (SSs) play important roles in the synthesis of cassava starch. However, the expression characteristics of the cassava SSs genes have not been elucidated. In this study, the gene and its promoter, from SC8 cassava cultivars, were respectively isolated by PCR amplification.

Clinical, histological and direct immunofluorescence features in oral mucosal patches striae diseases with malignant potential.

Background/purpose: Oral mucosal patches striae diseases (OMPSD) represent an important category of oral mucosal disease, most of which may have malignant potential (OMPSD-MP). The differential diagnosis is challenging due to overlap of their clinical and pathological features.

Materials And Methods: 116 OMPSD-MP patients were included in this cross-sectional study from November 2019 to February 2021, including oral lichen planus (OLP), oral lichenoid lesions (OLL), discoid lupus erythematosus (DLE), oral submucous fibrosis (OSF) and oral leukoplakia (OLK).

[Clinical application of plasma exchange combined with continuous veno-venous hemofiltration dialysis in children with refractory Kawasaki disease shock syndrome].

Objectives: To study the role of plasma exchange combined with continuous blood purification in the treatment of refractory Kawasaki disease shock syndrome (KDSS).

Methods: A total of 35 children with KDSS who were hospitalized in the Department of Pediatric Intensive Care Unit, Hunan Children's Hospital, from January 2019 to August 2022 were included as subjects. According to whether plasma exchange combined with continuous veno-venous hemofiltration dialysis was performed, they were divided into a purification group with 12 patients and a conventional group with 23 patients.

Nutritional status in patients with active pulmonary tuberculosis and new nutritional risk screening model for active tuberculosis: a national, multicenter, cross-sectional study in China.

Background: Tuberculosis (TB) remains a significant challenge for public health and is closely associated with malnutrition; however, few studies have attempted to screen malnutrition among TB patients. The study aimed to evaluate the nutrition status and build a new nutritional screening model for active TB.

Methods: A retrospective, multicenter, large cross-sectional study was conducted in China from 1 January 2020 to 31 December 2021.

[Application value of metagenomic next-generation sequencing for pathogen detection in childhood agranulocytosis with fever].

Objectives: To study the application value of metagenomic next-generation sequencing (mNGS) for pathogen detection in childhood agranulocytosis with fever.

Methods: A retrospective analysis was performed on the mNGS results of pathogen detection of 116 children with agranulocytosis with fever who were treated from January 2020 to December 2021. Among these children, 38 children with negative mNGS results were enrolled as the negative group, and 78 children with positive results were divided into a bacteria group (=22), a fungal group (=23), and a viral group (=31).

[Effects of nitrogen deposition and biochar application on soil NO fluxes in a Moso bamboo plantation].

In July 2019-July 2020, we conducted a field trial to examine the effects of nitrogen addition (60 kg N·hm·a), biochar application (10 t·hm), and their combination on soil NO emission and the relationship between soil NO emission and environmental factors in a typical Moso bamboo () plantation in Hangzhou City of Zhejiang Province. Soil NO flux of Moso bamboo plantation was measured by the static chamber-gas chromatography technique. The results showed that nitrogen addition treatment increased the annual cumulative NO emission by 14.

MiR-125b enhances autophagic flux to improve septic cardiomyopathy via targeting STAT3/HMGB1.

We explore the role of miR-125b in septic cardiomyopathy, focusing on miR-125b/STAT3/HMGB1 axis. CLP mouse model and LPS-stimulated primary rat cardiomyocytes (CMs) and H9C2 cell were used as in vivo and in vitro models of septic cardiomyopathy, respectively. qRT-PCR and western blot were performed to measure expression levels of miR-125b, STAT3, HMGB1, and autophagy-related proteins.

Penicilliosis marneffei in HIV negative children: three case reports.

This study aimed to report the clinical characteristics of penicilliosis marneffei (PSM) in three children negative to HIV. Three children were diagnosed with PSM in the Department of Emergency Medicine, Hunan Children's Hospital between February 2016 to July 2020. The clinical characteristics, laboratory findings, and concomitant diseases were recorded, and the related literatures were reviewed.

Kikuchi's disease with hemophagocytic lymphohistiocytosis: A case report and literature review.

Introduction: Kikuchi's disease (KD) is a rare form of necrotizing lymphadenitis that rarely occurs in association with hemophagocytic lymphohistiocytosis (HLH) in children.

Patient Concerns: We report the case of a 4-year-5-month-old boy who suffered from fever, cervical lymphadenopathy, pancytopenia, hypertriglyceridemia, splenomegaly, low NK cell activity.

Diagnoses: A diagnosis of KD with HLH was made based on the results of biopsy of cervical lymph node and HLH-2004 trial guidelines.

[Vasovagal syncope or postural orthostatic tachycardia syndrome in children with neurological symptoms at disease onset: a clinical analysis of 88 cases].

Objective: To study the clinical features of vasovagal syncope (VVS) and postural orthostatic tachycardia syndrome (POTS) in children with neurological symptoms at disease onset.

Methods: A retrospective analysis was performed on the medical data of 88 children with the initial symptoms of the nervous system, such as transient loss of consciousness, dizziness, headache, and convulsion, who were finally diagnosed with VVS or POTS.

Results: Of the 88 children, there were 35 boys (40%) and 53 girls (60%), with an age of 4-15 years.

[Effect of Conditioning Agent Combined with Flooding Measures on Absorption and Accumulation of Cadmium in Rice].

In order to evaluate the effects and mechanisms of flooding measures, soil conditioner, silicon mineral fertilizer and sprayed foliar fertilizer, gypsum powder, and their multiple treatments for reducing Cd accumulation in rice grown in Cd-contaminated soil. A plot experiment was conducted in three different Cd-contaminated soils. The results showed that flooding measures, a single application of conditioning agents, and combined application and flooding treatment can reduce soil-available Cd and the Cd content in various organs of rice with 6.

Ground observation result of an OH radical hyper-resolution spectrometer for the middle and upper atmosphere.

OH radicals in the upper and middle atmosphere are important oxidants and play an important role in atmospheric photochemistry. A hyper-resolution spectrometer based on 308 nm glow was developed for obtaining OH radical concentration data in the upper and middle atmosphere. In order to verify the performance of the OH radical hyper-resolution spectrometer, several comprehensive ground experiments were carried out in this paper.

Polarization sensitivity error analysis and measurement of a greenhouse gas monitoring instrument.

Greenhouse gas monitoring instruments (GMI) are spatial heterodyne spectroscopy (SHS) sensors that monitor greenhouse gases (GHG) from space. Due to several kinds of polarization-sensitive optical elements in GMIs, to some extent, the instrument becomes a polarization-sensitive sensor. Its polarization sensitivity will reduce the radiometric accuracy and spectral inversion accuracy of GHG column concentration.

[Bioavailability of Silicon Fertilizer Coupled Water Management on Soil Bioavailability and Cumulative Control of Rice in Compound Contaminated Paddy Soils].

The effect of wet irrigation (CK), agronomic measure flooding (WF), instantaneous silicon fertilizer combined with flooding measures (FYsi), mineral silicon fertilizer combined with flooding measures (FKsi), and a mix of two kinds of silicon fertilizer combined with flooding measures (FYK) on the bio-availability of As and Cd in soil and the accumulation of As and Cd in rice were investigated by pot experiments. The results showed that the pH of the soils combined with flooding measures was increased by 0.12-0.

[Effect of Warm Acupuncture on the Levels of Serum Immunoglobulin E, Interleukin-1 β and Tumor Necrosis Factor-α in Rats with Allergic Rhinitis].

Objective: To observe the effect of warm acupuncture on behavior and contents of serum immunoglobulin E(IgE), interleukin-1 β(IL-1 β) and tumor necrosis factor-α(TNF-α) in allergic rhinitis(AR) rats, so as to explore its mechanism underlying improving AR.

Methods: Forty Wistar rats were randomly divided into four groups: control group, model group, medication group and warm acupuncture group(10 rats/group). The AR model was established by intraperitoneal injection of sensitization and nasal drip.

Alignment error analysis of detector array for spatial heterodyne spectrometer.

Spatial heterodyne spectroscopy (SHS) is a new spatial interference spectroscopy which can achieve high spectral resolution. The alignment error of the detector array can lead to a significant influence with the spectral resolution of a SHS system. Theoretical models for analyzing the alignment errors which are divided into three kinds are presented in this paper.

Data processing error analysis based on Doppler asymmetric spatial heterodyne measurement.

The Doppler asymmetric spatial heterodyne (DASH) interferometer provides the capability to retrieve wind speed in the upper atmosphere. The data processing leads to a significant retrieving error with the development of wind precision. The influence of window parameters on the isolated interferogram is analyzed theoretically.

The Research of Flatfielding Correction Method for Spatial Heterodyne Spectrometer at Systematic Level.

It can’t satisfy the requirement of correction for response non-uniformity at systematic levelif only if the array detector for spatial heterodyne spectrometer is corrected. Traditional methods, such as irradiation with uniform source and column-flat-fielding, are not suitable for spatial heterodyne spectrometer. The article expounds convection arm-blocking method for spatial heterodyne spectrometer briefly at first.

[The Research of Spatial Heterodyne Raman Spectroscopy with Standoff Detection].

Spatial heterodyne Raman spectroscopy (SHRS) is a new type of Raman spectroscopic detection technique with characteristics of high optical throughout, high spectral resolution, and no moving parts. SHRS is very suitable for the planetary exploration missions, which can be used to the analysis of minerals and find the biomarkers maybe exist on the surface of planetary. The authors have applied the technique to the standoff Raman spectroscopic detection, analyzed the main characteristics, including spectral resolution, bandpass and signal to noise (SNR), of standoff SHRS and proved it through experiments.

[Error Correction of Spectral Calibration for Hyper-Spectral Atmosphere CO2 Monitoring Instrument].

The detection of hyper-spectral atmosphere CO2 needs remote sensor to be characterized and calibrated precisely while spectral calibration is the most basic work. The high uncertainty of wavelength calibration coefficient is a big problem as to the traditional laboratory calibration methods. In order to solve this problem, the research of error correction of spectral calibration based on gas absorption principle is carried out.

[Study on Asymmetric Spatial Heterodyne Spectroscopy].

Restrictive relationship exists between spectral resolution, spectral range and number of pixels of traditional Spatial Heterodyne Spectroscopy (SHS). The main difference between Asymmetric Spatial Heterodyne Spectroscopy (ASHS) and SHS accelerates the space of one grating from the beamsplitter. It greatly increases spectral resolution while system parameters remain unchanged.

Folic acid protects against arsenic-mediated embryo toxicity by up-regulating the expression of Dvr1.

As a nutritional factor, folic acid can prevent cardiac and neural defects during embryo development. Our previous study showed that arsenic impairs embryo development by down-regulating Dvr1/GDF1 expression in zebrafish. Here, we investigated whether folic acid could protect against arsenic-mediated embryo toxicity.

[Study on the Spectral Characteristics of the Narrow-Band Filter in SHS].

The spectral response of spatial heterodyne spectroscopy (SHS) is determined by the spectrum property of narrow-band filter. As discussed in previous studies, the symmetric heterodyned interferogram of high frequency waves modulated by SHS and lack of sample lead to spectral confusion, which is associated with the true and ghost spectra. Because of the deviation from theoretical index of narrow-band filter in the process of coating, the boarded spectral response and middle wave shift are presented, and conditions in the theoretical Littrow wavelength made the effective wavelength range of SHS reduced.