Publications by authors named "Hai-Xin Liu"

Article Synopsis
  • Portulaca oleracea L. (commonly known as purslane) is recognized for its edible and medicinal benefits, historically used in traditional medicine for diuretic and other therapeutic properties.
  • The focus of current research on its polysaccharide component (POP) highlights its diverse biological activities, particularly in immune system modulation, prompting extensive studies on its extraction and characterization.
  • This review aims to clarify the pharmacological mechanisms and molecular pathways of POP while identifying gaps in current knowledge and proposing new avenues for research to enhance understanding of its health benefits.
View Article and Find Full Text PDF
Article Synopsis
  • Traditional Chinese medicine suggests that herbs like Huangqi and Danggui can enhance Qi, boosting immunity to help fight tumors.
  • The study used various methods to test the effectiveness of these herbs in cancer treatment, finding that their combination is more potent than either one alone.
  • Key findings suggest that specific compounds in the combination target PIK3R1, enhancing immune response and showing significant anti-tumor effects, especially against breast cancer.
View Article and Find Full Text PDF

Background: Galactosemia is an autosomal recessive disorder resulting from an enzyme defect in the galactose metabolic pathway. The most severe manifestation of classic galactosemia is caused by galactose-1-phosphate uridylyltransferase (GALT) deficiency, and this condition can be fatal during infancy if left untreated. It also may result in long-term complications in affected individuals.

View Article and Find Full Text PDF
Article Synopsis
  • * Overexpression of CD36 is linked to negative effects such as lipid accumulation and inflammation, making it a potential target for new treatments.
  • * The review focuses on the structure and function of CD36 in atherosclerosis and discusses various natural products and drugs that aim to inhibit CD36 to prevent and treat this disease effectively.
View Article and Find Full Text PDF

Fast and quantitative detection of dopamine (DA) is highly desirable but still challenging in the clinical diagnosis due to the complexity of the biological samples. Herein, a novel peony-like 3D-MoS/Graphene (peony-like 3D-MoS/GR) nanomaterial is designed and characterized. The nanomaterial exhibits outstanding the peroxidase-like activity, which can be employed as a nanozyme for facile and fast colorimetric determination of dopamine.

View Article and Find Full Text PDF

Although Danhong injection (DHI) is the most widely prescribed Chinese medicine for both stroke and coronary artery disease (CAD), its underlying common molecular mechanisms remain unclear. An integrated network pharmacology and experimental verification approach was used to decipher common pharmacological mechanisms of DHI on stroke and CAD treatment. A compound-target-disease & function-pathway network was constructed and analyzed, indicating that 37 ingredients derived from DH (Salvia miltiorrhiza Bge.

View Article and Find Full Text PDF

Sex hormone estrogen is one of the most active intrinsic angiogenesis regulators; its therapeutic use has been limited due to its carcinogenic potential. Plant-derived phytoestrogens are attractive alternatives, but reports on their angiogenic activities often lack in-depth analysis and sometimes are controversial. Herein, we report a data-mining study with the existing literature, using IPA system to classify and characterize phytoestrogens based on their angiogenic properties and pharmacological consequences.

View Article and Find Full Text PDF

Background: Hainan Island is located around the conjunction of East Asia and Southeast Asia, and during the Last Glacial Maximum (LGM) was connected with the mainland. This provided an opportunity for the colonization of Hainan Island by modern human in the Upper Pleistocene. Whether the ancient dispersal left any footprints in the contemporary gene pool of Hainan islanders is debatable.

View Article and Find Full Text PDF

Objective: To analyze the constituents of the essential oils extracted from nine samples of commercial seeds of Myristica fragrans Houtt respectively and to provide qualities control foundations.

Method: Water steam distillation and GC-MS were used.

Result: 95-118 compounds were separated respectively.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Notice

Message: fwrite(): Write of 34 bytes failed with errno=28 No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 272

Backtrace:

A PHP Error was encountered

Severity: Warning

Message: session_write_close(): Failed to write session data using user defined save handler. (session.save_path: /var/lib/php/sessions)

Filename: Unknown

Line Number: 0

Backtrace: