Publications by authors named "Hai-Xiao Li"
Article Synopsis
- - The study investigates the protective effects of Growth arrest-specific gene 6 (Gas6) against cognitive and emotional impairments in sepsis survivors, specifically focusing on sepsis-associated encephalopathy (SAE).
- - Researchers induced sepsis in mice and then administered Gas6, finding that it significantly improved neurological functions and reduced brain swelling and blood-brain barrier (BBB) damage.
- - The results indicate that Gas6 could potentially help reverse neurological deficits and protect against SAE by restoring BBB integrity and increasing the expression of critical tight junction proteins.
Paraquat (PQ) intoxication causes thousands of mortalities every year, worldwide. Its pulmonary-targeted accumulation and the acute lung injury it subsequently causes, remain a challenge for detoxification treatment. A previous study has demonstrated that the upregulation of nuclear factor erythroid-2 related factor 2 (Nrf2) prevents PQ toxicity in cell line and murine models.
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