Association between Non-high-density Lipoprotein Cholesterol to High-density Lipoprotein Cholesterol Ratio (NHHR) and Stroke among Adults in the USA: A Cross-Sectional NHANES Study.

Objective: The relationship between non-high-density lipoprotein (NHDL) cholesterol to high-density lipoprotein cholesterol (HDL-C) ratio (NHHR) and stoke remains unknown. This study aimed to evaluate the association between the adult NHHR and stroke occurrence in the United States of America (USA).

Methods: To clarify the relationship between the NHHR and stroke risk, this study used a multivariable logistic regression model and a restricted cubic spline (RCS) model to investigate the association between the NHHR and stroke, and data from the National Health and Nutrition Examination Survey (NHANES) from 2005 to 2018.

Porto-Sinusoidal Vascular Disease: A New Nomenclature Different from Idiopathic Non-Cirrhotic Portal Hypertension.

Background And Aims: Porto-sinusoidal vascular disease (PSVD) as a novel clinical conception was modified on the basis of idiopathic non-cirrhotic portal hypertension (INCPH). This study aimed to compare the clinical, biochemical histological features and prognosis between the diagnostic criteria for PSVD and that of INCPH.

Methods: A total of 65 patients who underwent liver biopsies were analyzed retrospectively.

Multi-Gene Phylogenetic Analyses Reveals Gen. Nov. and New Contributions to Xylariaceae (Ascomycota) from China.

An in-depth study of the phylogenetic relationships of species associated with nutshells of fruits and seeds within the genus and related genera of Xylaceaecea was conducted in China. The multi-gene phylogenetic analyses were carried out based on ITS, RPB2, and TUB sequences of 100 species of 16 known genera in Xylariaceae around the world. Based on molecular phylogenetic analyses, morphological observations, and ecological habitats, a new genus, , is established to accommodate four new species, viz.

Multi-gene phylogenetic and taxonomic contributions to (Ascomycota) associated with fallen fruits from China.

Morphological and phylogenetic analyses on samples of species associated with fallen fruits from China were carried out, and two new species were described, namely and . is found on fallen fruits of , and characterized by stromata dichotomously branched several times with long acute sterile apices, fertile parts roughened with perithecia and tomentose, and ellipsoid to fusiform ascospores. differs in its very small stromata with dark brown tomentum, light brown ascospores with an inconspicuous straight germ slit, and grows on leguminous pods.

Multi-Locus Phylogeny and Morphology Reveal Two New Species of (Hypoxylaceae, Xylariales) from Motuo, China.

Hypoxylaceous fungi are abundant in China, but their discovery and report are uneven in various provinces, with more fungi in Yunnan and Hainan and fewer fungi in Tibet. During the investigation of macro-fungi in Motuo county, Tibet Autonomous Region, we collected a number of xylarialean specimens. Six hypoxylaceous specimens growing on dead angiosperm were collected from the forests of Motuo county, and they were described and illustrated as two new species in based on a combination of morphological characters and molecular evidence.

Taxonomic and phylogenetic contributions to Diatrypaceae from southeastern Tibet in China.

In this study, we investigated the diversity of diatrypaceous fungi from southeastern Tibet in China. The phylogenetic analyses were carried out based on ITS and β-tubulin sequences of 75 taxa of Diatrypaceae from around the world. Based on a combination of morphological features and molecular evidence, a new genus-, with three new species-, , and , and a new combination-, were revealed by the materials in China.

Antidiabetic lanostane triterpenoids from the fruiting bodies of Ganoderma weberianum.

Eight previously undescribed lanostane triterpenoids, ganodeweberiols A ∼ H (1-8), together with eighteen known compounds (9-26), were isolated from the fruiting bodies of Ganoderma weberianum. The structures and absolute configurations of the new compounds were determined by extensive spectroscopic analysis, as well as NMR chemical shifts and electronic circular dichroism (ECD) calculations. Compounds 2, 7, 12, and 14 showed significant α-glucosidase inhibitory activity with IC values ranging from 35.

Global Taxonomy and Phylogeny of Irpicaceae (Polyporales, Basidiomycota) With Descriptions of Seven New Species and Proposals of Two New Combinations.

The phylogenetic analyses of the family Irpicaceae were carried out based on a complete global sampling. The dataset that included concatenated ITS1-5.8S-ITS2 and nrLSU sequences of 67 taxa of Irpicaceae from around the world was subjected to the maximum likelihood analyses and Bayesian inference.

Three New Species of (Xylariales, Ascomycota) on a Multigene Phylogeny from Medog in Southwest China.

During a survey of hypoxylaceous fungi in Medog county (Tibet Autonomous Region, China), three new species, including , , and , were described and illustrated based on morphological and multi-gene phylogenetic analyses. is characterized by its yellow-brown stromatal granules, light-brown to brown ascospores, and frequently indehiscent perispore. is morphologically and phylogenetically related to but differs in having larger ascospores with straight spore-length germ slit and conspicuously coil-like perispore ornamentation.

Subclassifying triple-negative breast cancers and its potential clinical utility.

The molecular subtyping of triple-negative breast cancer (TNBC) is critical to guiding individualized patient treatment. In this study, we sought to characterize the clinicopathologic features of TNBC subtypes and to identify correlates of patient survival in an effort to provide a robust foundation for treatment planning. We additionally assessed PD-L1 expression in Chinese TNBC patients and evaluated the relationship between such expression and immunotherapeutic treatment outcomes.

Three new species (Xylariaceae, Xylariales) on fallen leaves from Hainan Tropical Rainforest National Park.

Three new species of on fallen leaves in Hainan Province of China are described and illustrated, based on morphological and molecular evidence. is found on fallen leaves of and featured by thread-like stromata with a long sterile filiform apex. Phylogenetically, is closely related to an undescribed sp.

In vitro antifungal activities, molecular docking, and DFT studies of 4-amine-3-hydrazino-5-mercapto-1,2,4-triazole derivatives.

Six disubstituted Schiff base compounds were synthesized (A1-A6) and characterized using infrared spectroscopy (IR), elemental analyses (EA), H NMR, C NMR and HRMS spectroscopic techniques. Crystal structure of A1 has been determined by single crystal X-ray diffraction. The antifungal activities against three fungi were assessed, and the results showed that compounds of A1 and A2 have good activity for Wheat gibberellic with EC value of 15.

Global Phylogeny and Taxonomy of the Wood-Decaying Fungal Genus (Polyporales, Basidiomycota).

An in-depth study of the phylogeny and taxonomy of the corticioid genus (Phanerochaetaceae) was conducted. Phylogenetic analyses of the ITS1-5.8S-ITS2 and nrLSU sequences demonstrated that is a strongly supported clade which is distinct from its sister clades of , , and .

Four new corticioid species in Trechisporales (Basidiomycota) from East Asia and notes on phylogeny of the order.

Four new species in Trechisporales from East Asia, , , and , are described and illustrated, based on morphological and molecular evidence. The phylogeny of Trechisporales was inferred from a combined dataset of ITS-nrLSU sequences. In the phylogenetic tree, formed a family-level clade of its own, sister to the Hydnodontaceae clade formed by all other genera.

Activities of Endogenous Lipase and Lipolysis Oxidation of Low-Salt Lactic Acid-Fermented Fish (Decapterus maruadsi).

There is increasing demand for low-salt meat products that retain traditional flavors. In this study, dry-salted fish (Decapterus maruadsi) were processed by 2 methods to obtain traditional salted fish (HS) and low-salt lactic acid-fermented fish (LAF). The relationship between lipolysis and lipid oxidation was investigated by evaluating changes in endogenous lipase (lipolytic enzymes; lipoxygenase, LOX), free fatty acid composition, thiobarbituric acid reactive substances (TBARS), and peroxide value (POV) during processing.

Prevalence and Treatment of Children's Asthma in Rural Areas Compared with Urban Areas in Beijing.

Background: The prevalence of childhood asthma has been increasing in China. This study aimed to compare the prevalence, diagnosis, and treatment of asthmatic children from urban and rural areas in Beijing, China.

Methods: Schools, communities, and kindergartens were randomly selected by cluster random sampling from urban and rural areas in Beijing.

1-[6-(3,5-Di-methyl-pyrazol-1-yl)-1,2,4,5-tetra-zin-3-yl]guanidin-2-ium perchlorate methanol monosolvate.

In the title solvated salt, C8H12N9 (+)·ClO4 (-)·CH3OH, the dihedral angle between the tetra-zine and pyrazole rings is 26.05 (7)°. The two N atoms bonded to the 1,2,4,5-tetra-zine ring deviate from the plane defined by its four N atoms by 0.

3,3-Dinitro-azetidinium chloride.

In the title gem-dinitro-azetidinium chloride salt, C3H6N3O4(+)·Cl(-), the cations and anions lie on a mirror plane. The azetidine ring is virtually planar, with a mean deviation from the plane of 0.0569 Å.

Three new lanostanoid triterpenes from the fruiting bodies of Ganoderma tropicum.

Three new lanostanoid triterpenes, 3β,7β,15β-trihydroxy-11,23-dioxo-lanost-8,16-dien-26-oic acid (1), 3β,7β,15β-trihydroxy-11,23-dioxo-lanost-8,16-dien-26-oic acid methyl ester (2), and 3β,15β-dihydroxy-7,11,23-trioxo-lanost-8,16-dien-26-oic acid methyl ester (3) were isolated from the EtOAc extract of the fruiting bodies of Ganoderma tropicum. Their structures were elucidated on the basis of 1D and 2D NMR spectroscopy as well as MS. The bioassay of inhibitory activity against acetylcholinesterase (AChE) of these isolates was evaluated and compound 2 exhibited definite inhibitory activity against AChE.

1-Benzoyl-3,3-dinitro-azetidine.

In the title gem-dinitro-azetidine derivative, C(10)H(9)N(3)O(5), the azetidine ring is almost planar, the maximum value of the endocyclic torsion angle being 0.92 (14)°. The gem-dinitro groups are mutually perpendicular and the dihedral angle between the azetidine and benzene rings is 46.

1-(2,4-Dinitro-phen-yl)-3,3-dinitro-azetidine.

In the title compound, C(9)H(7)N(5)O(8), the dihedral angle between the mean plane of the azetidine ring and that of the benzene ring is 26.1 (1)°; the planes of the two nitro groups of the azetidine ring are aligned at 88.7 (1)°.

Nonisothermal decomposition kinetics and computational studies on the properties of 2,4,6,8-tetranitro-2,4,6,8-tetraazabicyclo[3,3,1]onan-3,7-dione (TNPDU).

The thermal decomposition and the nonisothermal kinetics of the thermal decomposition reaction of 2,4,6,8-tetranitro-2,4,6,8-tetraazabicyclo[3,3,1]onan-3,7-dione (TNPDU) were studied under the nonisothermal condition by differential scanning calorimetry (DSC) and thermogravimetry-derivative thermogravimetry (TG-DTG) methods. The kinetic model function in differential form and the value of Ea and A of the decomposition reaction of TNPDU are f(alpha) = 3(1 - alpha)[-ln(1 - alpha)](2/3), 141.72 kJ mol(-1), and 10(11.